Disseminated metastatic tissue calcification after orthotopic liver transplantation: A case report

Deguchi, K.; Ueno, T.; Matsuura, R. et al.

Transplantation Proceedings, 2016, 48(1), 251-254

アクセス数:1,059件（2025-07-26 12:28 集計）

固定URL: https://hdl.handle.net/11094/100146

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タイトル
Disseminated metastatic tissue calcification after orthotopic liver transplantation: A case report
著者
NRID
1000000747082 1000000747082
researchmap permalink
deguchi_koichi deguchi_koichi
Scopus Author ID
57139781700 57139781700
著者名
Deguchi, K.
NRID
1000010456957 1000010456957
ORCID
0000-0002-4639-8814 0000-0002-4639-8814
researchmap permalink
ueno-pedsurg ueno-pedsurg
Scopus Author ID
21743992300 21743992300
著者名
Ueno, T.
NRID
1000000747412 1000000747412
著者名
Matsuura, R.
NRID
1000070467570 1000070467570
著者名
Yamanaka, H.
NRID
1000000432477 1000000432477
著者名
Nara, K.
NRID
1000000448060 1000000448060
著者名
Uehara, S.
NRID
1000010397698 1000010397698
researchmap permalink
yukotazuke-osaka yukotazuke-osaka
Scopus Author ID
7006109798 7006109798
ORCID
0000-0002-8335-0414 0000-0002-8335-0414
著者名
Tazuke, Y.
NRID
1000080423169 1000080423169
researchmap permalink
KazuBe KazuBe
著者名
Bessho, K.
NRID
1000030252670 1000030252670
researchmap permalink
okuyamahiroomi okuyamahiroomi
Scopus Author ID
35496082300 35496082300
ORCID
0000-0002-1347-282X 0000-0002-1347-282X
著者名
Okuyama, H.
内容
Deguchi K., Ueno T., Matsuura R., et al. Disseminated metastatic tissue calcification after orthotopic liver transplantation: A case report. Transplantation Proceedings 48, 251 (2016); https://doi.org/10.1016/J.TRANSPROCEED.2015.12.033.
抄録
Background: Hypercalcemia has been observed in patients after liver transplantation. However, it is rare that the hypercalcemia induced disseminated tissue calcification and heart failure. Case Report: We report a rare case of heart failure caused by disseminated metastatic tissue calcification that involved extensive progressive myocardial calcification after liver transplantation. A 20-year-old man with end-stage liver disease due to biliary atresia underwent ABO-incompatible living donor liver transplantation. After successful transplantation, he suffered from antibody-mediated rejection. Subsequently, ABO-matched cadaveric liver retransplantation was successfully performed. Hypercalcemia developed gradually following the second transplantation. His serum calcium level increased to 18.3 mg/dL with sudden onset of ventricular tachycardia. Although he was resuscitated with a cardiopulmonary support device, he died of heart and liver failure. Histopathologic examination revealed systemic disseminated metastatic tissue calcification, including massive myocardial calcification. Conclusion: Progressive worsening of hypercalcemia resulted in disseminated metastatic tissue calcification and massive metastatic myocardial calcification, which led to heart failure after liver transplantation. Because hypercalcemia after liver transplantation can cause fatal tissue calcification, early intervention for hypercalcemia should be considered.
出版者
Elsevier USA
収録物名
Transplantation Proceedings
巻(号)
48(1)
ページ
251-254
刊行年月
2016-01-01
言語
英語
ハンドルURL
https://hdl.handle.net/11094/100146
PISSN
00411345
eISSN
18732623
関連情報 (isVersionOf)
DOI (出版社版)
https://doi.org/10.1016/J.TRANSPROCEED.2015.12.033
アクセス権
open access
権利情報
© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
出版タイプ
Accepted Manuscript
カテゴリ
学術雑誌論文 Journal Article