Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study

Ohata, Yuka; Kabayama, Mai; Godai, Kayo; Kido, Michiko; Li, Yaya; Akagi, Yuya; Murakami, Naoko; Yoshida, Hiroko; Hosokawa, Mariko; Tachibana, Yuka; Fukata, Yuka; Anzai, Chihiro; Hatta, Kaoru; Maeyama, Yurie; Wada, Arisa; Hashimoto, Sumiyo; Hatanaka, Hiromi; Higashi, Makiko; Kikuchi, Takeshi; Terauchi, Keiji; Matsuno, Fumie; Nagayoshi, Sho; Asayama, Kei; Ohkubo, Takayoshi; Rakugi, Hiromi; Tabara, Yasuharu; Kamide, Kei

doi:https://doi.org/10.1038/s41440-025-02145-8

Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study

Ohata, Yuka; Kabayama, Mai; Godai, Kayo et al.

Hypertension Research, 2025

アクセス数:2,376件（2025-08-30 02:15 集計）

固定URL: https://hdl.handle.net/11094/100451

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タイトル	Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study
著者	著者名 Ohata, Yuka
	NRID 1000050635498 1000050635498 ORCID 0000-0003-1394-1152 0000-0003-1394-1152 researchmap permalink kabayama kabayama Scopus Author ID 57031780400 57031780400 著者名 Kabayama, Mai
	NRID 1000030708681 1000030708681 researchmap permalink vince vince Scopus Author ID 56781372400 56781372400 著者名 Godai, Kayo
	NRID 1000000706913 1000000706913 researchmap permalink 051010 051010 Scopus Author ID 56086201900 56086201900 著者名 Kido, Michiko
	NRID 1000060982030 1000060982030 researchmap permalink lia lia 著者名 Li, Yaya
	researchmap permalink yuya-akagi yuya-akagi 著者名 Akagi, Yuya
	著者名 Murakami, Naoko
	著者名 Yoshida, Hiroko
	著者名 Hosokawa, Mariko
	著者名 Tachibana, Yuka
	著者名 Fukata, Yuka
	著者名 Anzai, Chihiro
	著者名 Hatta, Kaoru
	著者名 Maeyama, Yurie
	著者名 Wada, Arisa
	著者名 Hashimoto, Sumiyo
	著者名 Hatanaka, Hiromi
	著者名 Higashi, Makiko
	著者名 Kikuchi, Takeshi
	著者名 Terauchi, Keiji
	著者名 Matsuno, Fumie
	著者名 Nagayoshi, Sho
	NRID 1000080431518 1000080431518 著者名 Asayama, Kei
	NRID 1000060344652 1000060344652 著者名 Ohkubo, Takayoshi
	NRID 1000020252679 1000020252679 ORCID 0000-0001-6508-4338 0000-0001-6508-4338 researchmap permalink read0042763 read0042763 Scopus Author ID 57202699453 57202699453 著者名 Rakugi, Hiromi
	NRID 1000000268749 1000000268749 researchmap permalink yasuharu.tabara yasuharu.tabara 著者名 Tabara, Yasuharu
	NRID 1000080393239 1000080393239 researchmap permalink kamide kamide Scopus Author ID 7102978326 7102978326 ORCID 0000-0003-1720-2218 0000-0003-1720-2218 著者名 Kamide, Kei
キーワード等	Community-dwelling older adults
	Frailty
	Home blood pressure
	Office blood pressure
	Self-measured
内容	The version of record of this article, first published in Hypertension Research, is available online at Publisher’s website: https://doi.org/10.1038/s41440-025-02145-8.
抄録	The relationship between frailty and blood pressure (BP) is inconsistent, and limited research has compared BP by frailty status using long-term home BP measurements. We aimed to identify office and home BP and determine differences according to frailty status, stratified by taking antihypertensives in community-dwelling older adults. This cross-sectional study was part of the ongoing non-randomized intervention NOSE study. Participants were aged ≥ 64 years. Frailty was categorized robust, pre-frailty, or frailty using the revised Japanese version of the Cardiovascular Health Study criteria. Office BP was measured in survey settings, and each participant was instructed to take home BP. We used the average home BP for 4 weeks post-survey. An analysis of covariance analyzed the relationship between frailty and office and home BP, and their differences stratified by antihypertensive use. We included 418 older participants (mean age: 72.8 years); 39.5% were male, 40.4% were taking antihypertensives, and 6.7% had frailty. Individuals with frailty taking antihypertensives had higher home morning systolic BP (SBP) than those with robust (134.2 vs. 145.7 mmHg, P = 0.018) and pre-frailty (135.6 vs. 145.7 mmHg, P = 0.024). The difference between office and morning home SBP in treated participants was 7.1 mmHg (robust), 4.7 mmHg (pre-frailty), and −5.1 mmHg (frailty), showing significant differences (robust vs. frailty: P = 0.005, pre-frailty vs. frailty: P = 0.016). Home morning SBP was higher in individuals with frailty taking antihypertensives compared to those without frailty, and it may be higher than office BP. Individuals with frailty should measure home BP for good BP control.
出版者	Springer Nature
収録物名	Hypertension Research
刊行年月	2025-02-14
言語	英語
ハンドルURL	https://hdl.handle.net/11094/100451
PISSN	09169636
eISSN	13484214
関連情報 (isIdenticalTo)	DOI (出版社版) https://doi.org/10.1038/s41440-025-02145-8
アクセス権	open access
権利情報	This article is licensed under a Creative Commons Attribution 4.0 International License.
出版タイプ	Version of Record
カテゴリ	学術雑誌論文 Journal Article

資源タイプ	学術雑誌論文
ローカル資源タイプ	学術雑誌論文
DCTERMS.bibliographicCitation	Hypertension Research. 2025
DC.title	Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study
DC.creator	Ohata, Yuka
	Kabayama, Mai
	Godai, Kayo
	Kido, Michiko
	Li, Yaya
	Akagi, Yuya
	Murakami, Naoko
	Yoshida, Hiroko
	Hosokawa, Mariko
	Tachibana, Yuka
	Fukata, Yuka
	Anzai, Chihiro
	Hatta, Kaoru
	Maeyama, Yurie
	Wada, Arisa
	Hashimoto, Sumiyo
	Hatanaka, Hiromi
	Higashi, Makiko
	Kikuchi, Takeshi
	Terauchi, Keiji
	Matsuno, Fumie
	Nagayoshi, Sho
	Asayama, Kei
	Ohkubo, Takayoshi
	Rakugi, Hiromi
	Tabara, Yasuharu
	Kamide, Kei
DC.publisher	Springer Nature
DC.language' scheme='DCTERMS.RFC1766	英語
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2025-02-14
DC.identifier	https://doi.org/10.1038/s41440-025-02145-8
DC.subject	Community-dwelling older adults
	Frailty
	Home blood pressure
	Office blood pressure
	Self-measured
DC.description	The version of record of this article, first published in Hypertension Research, is available online at Publisher’s website: https://doi.org/10.1038/s41440-025-02145-8.
DCTERMS.abstract	The relationship between frailty and blood pressure (BP) is inconsistent, and limited research has compared BP by frailty status using long-term home BP measurements. We aimed to identify office and home BP and determine differences according to frailty status, stratified by taking antihypertensives in community-dwelling older adults. This cross-sectional study was part of the ongoing non-randomized intervention NOSE study. Participants were aged ≥ 64 years. Frailty was categorized robust, pre-frailty, or frailty using the revised Japanese version of the Cardiovascular Health Study criteria. Office BP was measured in survey settings, and each participant was instructed to take home BP. We used the average home BP for 4 weeks post-survey. An analysis of covariance analyzed the relationship between frailty and office and home BP, and their differences stratified by antihypertensive use. We included 418 older participants (mean age: 72.8 years); 39.5% were male, 40.4% were taking antihypertensives, and 6.7% had frailty. Individuals with frailty taking antihypertensives had higher home morning systolic BP (SBP) than those with robust (134.2 vs. 145.7 mmHg, P = 0.018) and pre-frailty (135.6 vs. 145.7 mmHg, P = 0.024). The difference between office and morning home SBP in treated participants was 7.1 mmHg (robust), 4.7 mmHg (pre-frailty), and −5.1 mmHg (frailty), showing significant differences (robust vs. frailty: P = 0.005, pre-frailty vs. frailty: P = 0.016). Home morning SBP was higher in individuals with frailty taking antihypertensives compared to those without frailty, and it may be higher than office BP. Individuals with frailty should measure home BP for good BP control.
DC.rights	This article is licensed under a Creative Commons Attribution 4.0 International License.
DC.format	100451
citation_title	Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study
citation_author	Ohata, Yuka
	Kabayama, Mai
	Godai, Kayo
	Kido, Michiko
	Li, Yaya
	Akagi, Yuya
	Murakami, Naoko
	Yoshida, Hiroko
	Hosokawa, Mariko
	Tachibana, Yuka
	Fukata, Yuka
	Anzai, Chihiro
	Hatta, Kaoru
	Maeyama, Yurie
	Wada, Arisa
	Hashimoto, Sumiyo
	Hatanaka, Hiromi
	Higashi, Makiko
	Kikuchi, Takeshi
	Terauchi, Keiji
	Matsuno, Fumie
	Nagayoshi, Sho
	Asayama, Kei
	Ohkubo, Takayoshi
	Rakugi, Hiromi
	Tabara, Yasuharu
	Kamide, Kei
citation_publisher	Springer Nature
citation_language	英語
citation_date	2025-02-14
citation_journal_title	Hypertension Research
citation_doi	https://doi.org/10.1038/s41440-025-02145-8
citation_public_url	https://hdl.handle.net/11094/100451

Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study

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