学術雑誌論文

学術雑誌論文

text

Experimental Hematology. 2025, 148, p. 104795

Development and aging of resident endothelial stem cells in pre-existing blood vessels

Elsevier Inc.

英語

text

2025-07-25

https://doi.org/10.1016/j.exphem.2025.104795

Rahmawati F.N., Takakura N.. Development and aging of resident endothelial stem cells in pre-existing blood vessels. Experimental Hematology 148, 104795 (2025); https://doi.org/10.1016/j.exphem.2025.104795.

Organ-specific somatic stem cells play an important role in supporting tissue turnover and facilitating regeneration on injury. Hematopoietic stem cells are one of the most established organ-specific somatic cells that have been frequently used for transplantation therapy. Recently, there has been a growing interest in other organ-specific somatic cells, including vascular endothelial stem cells (VESCs). We have previously reported on the use of CD157 and CD200 as markers to isolate VESCs from adult mouse organs, particularly the liver. In this review, we aimed to summarize, based on our previous research, how CD157⁺CD200⁺ VESCs in the liver develop from the fetal stage to postnatal life, what transcriptional regulatory mechanisms govern them, and how VESCs change with aging.

This article is licensed under a Creative Commons Attribution 4.0 International License.

102650

Development and aging of resident endothelial stem cells in pre-existing blood vessels

Elsevier Inc.

英語

2025-07-25

Experimental Hematology

148

104795

https://doi.org/10.1016/j.exphem.2025.104795

https://hdl.handle.net/11094/102650