Altruism Enhances Frontal Alpha Asymmetry and Reduces Sympathetic Activity: A Multimodal EEG-ECG Study With Implications for Therapeutic Interventions

Orui, Junya; Shiraiwa, Keigo; Inoue, Takao; Ueda, Masaya; Ueno, Keita; Naito, Yasuo; Ishii, Ryouhei

doi:https://doi.org/10.1002/brb3.70747

Altruism Enhances Frontal Alpha Asymmetry and Reduces Sympathetic Activity: A Multimodal EEG-ECG Study With Implications for Therapeutic Interventions

Orui, Junya; Shiraiwa, Keigo; Inoue, Takao et al.

Brain and Behavior, 2025, 15(8), e70747

アクセス数:243件（2026-02-16 01:04 集計）

固定URL: https://hdl.handle.net/11094/102761

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タイトル	Altruism Enhances Frontal Alpha Asymmetry and Reduces Sympathetic Activity: A Multimodal EEG-ECG Study With Implications for Therapeutic Interventions
著者	NRID 1000030883970 1000030883970 著者名 Orui, Junya
	NRID 1000070908128 1000070908128 著者名 Shiraiwa, Keigo
	NRID 1000040779427 1000040779427 著者名 Inoue, Takao
	NRID 1000010965023 1000010965023 著者名 Ueda, Masaya
	著者名 Ueno, Keita
	NRID 1000040342224 1000040342224 著者名 Naito, Yasuo
	NRID 1000040372619 1000040372619 ORCID 0000-0002-4245-0953 0000-0002-4245-0953 researchmap permalink read0118527 read0118527 Scopus Author ID 7102883761 7102883761 著者名 Ishii, Ryouhei
キーワード等	altruism
	autonomic activity
	electroencephalography
	frontal alpha asymmetry
	neurophysiology
	social cognition
	therapeutic interventions
内容	Orui J., Shiraiwa K., Inoue T., et al. Altruism Enhances Frontal Alpha Asymmetry and Reduces Sympathetic Activity: A Multimodal EEG-ECG Study With Implications for Therapeutic Interventions. Brain and Behavior 15, e70747 (2025); https://doi.org/10.1002/brb3.70747.
抄録	Introduction: This study aimed to investigate neurophysiological differences between altruistic and selfish behaviors by simultaneously measuring electroencephalography (EEG) and electrocardiography (ECG). Specifically, we hypothesized that altruistic behavior would be associated with distinct patterns of cortical activity and autonomic responses. Methods: Thirty-one healthy participants (17 females; mean age: 20.00 ± 1.18 years) completed crafting tasks in a counterbalanced order under altruistic and selfish conditions. We measured and analyzed frontal alpha asymmetry (FAA) scores, cardiac sympathetic index (CSI), and cardiac vagal index (CVI). Additionally, we used eLORETA (exact-low resolution electromagnetic tomography) to examine current source density and functional connectivity patterns across brain regions. Results: The altruistic condition exhibited significantly higher FAA scores (p = 0.031, r = 0.45) and lower CSI (p = 0.048, Cohen's d = 0.37) compared to the selfish condition. Notably, novel correlations were observed between neurophysiological measures and specific brain regions. Specifically, FAA scores were associated with gamma activity in the anterior cingulate cortex during the altruistic condition (p = 0.071) and with precuneus activity during selfish behavior (p = 0.029). Additionally, distinct functional connectivity patterns were associated with autonomic activity in the altruistic condition. Parasympathetic activity negatively correlated with temporal-gamma connectivity (p = 0.002), and heart rate change negatively correlated with temporal-prefrontal theta connectivity (p = 0.048). Conclusions: Our findings reveal the intricate relationship between cortical activity, functional connectivity, and autonomic responses during altruistic versus selfish behaviors for the first time. This integrative approach sheds new light on the neural mechanisms underlying social cognition. This approach also has the potential to enhance our understanding of and ability to encourage prosocial behavior in various clinical and therapeutic settings.
出版者	John Wiley and Sons Ltd
収録物名	Brain and Behavior
巻(号)	15(8)
ページ	e70747
刊行年月	2025-08-21
言語	英語
ハンドルURL	https://hdl.handle.net/11094/102761
eISSN	21623279
関連情報 (isIdenticalTo)	DOI (出版社版) https://doi.org/10.1002/brb3.70747
アクセス権	open access
権利情報	This article is licensed under a Creative Commons Attribution 4.0 International License.
出版タイプ	Version of Record
カテゴリ	学術雑誌論文 Journal Article

資源タイプ	学術雑誌論文
ローカル資源タイプ	学術雑誌論文
DCMI資源タイプ	text
DCTERMS.bibliographicCitation	Brain and Behavior. 2025, 15(8), p. e70747
DC.title	Altruism Enhances Frontal Alpha Asymmetry and Reduces Sympathetic Activity: A Multimodal EEG-ECG Study With Implications for Therapeutic Interventions
DC.creator	Orui, Junya
	Shiraiwa, Keigo
	Inoue, Takao
	Ueda, Masaya
	Ueno, Keita
	Naito, Yasuo
	Ishii, Ryouhei
DC.publisher	John Wiley and Sons Ltd
DC.language' scheme='DCTERMS.RFC1766	英語
DC.type' scheme='DCTERMS.DCMIType	text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2025-08-21
DC.identifier	https://doi.org/10.1002/brb3.70747
DC.subject	altruism
	autonomic activity
	electroencephalography
	frontal alpha asymmetry
	neurophysiology
	social cognition
	therapeutic interventions
DC.description	Orui J., Shiraiwa K., Inoue T., et al. Altruism Enhances Frontal Alpha Asymmetry and Reduces Sympathetic Activity: A Multimodal EEG-ECG Study With Implications for Therapeutic Interventions. Brain and Behavior 15, e70747 (2025); https://doi.org/10.1002/brb3.70747.
DCTERMS.abstract	Introduction: This study aimed to investigate neurophysiological differences between altruistic and selfish behaviors by simultaneously measuring electroencephalography (EEG) and electrocardiography (ECG). Specifically, we hypothesized that altruistic behavior would be associated with distinct patterns of cortical activity and autonomic responses. Methods: Thirty-one healthy participants (17 females; mean age: 20.00 ± 1.18 years) completed crafting tasks in a counterbalanced order under altruistic and selfish conditions. We measured and analyzed frontal alpha asymmetry (FAA) scores, cardiac sympathetic index (CSI), and cardiac vagal index (CVI). Additionally, we used eLORETA (exact-low resolution electromagnetic tomography) to examine current source density and functional connectivity patterns across brain regions. Results: The altruistic condition exhibited significantly higher FAA scores (p = 0.031, r = 0.45) and lower CSI (p = 0.048, Cohen's d = 0.37) compared to the selfish condition. Notably, novel correlations were observed between neurophysiological measures and specific brain regions. Specifically, FAA scores were associated with gamma activity in the anterior cingulate cortex during the altruistic condition (p = 0.071) and with precuneus activity during selfish behavior (p = 0.029). Additionally, distinct functional connectivity patterns were associated with autonomic activity in the altruistic condition. Parasympathetic activity negatively correlated with temporal-gamma connectivity (p = 0.002), and heart rate change negatively correlated with temporal-prefrontal theta connectivity (p = 0.048). Conclusions: Our findings reveal the intricate relationship between cortical activity, functional connectivity, and autonomic responses during altruistic versus selfish behaviors for the first time. This integrative approach sheds new light on the neural mechanisms underlying social cognition. This approach also has the potential to enhance our understanding of and ability to encourage prosocial behavior in various clinical and therapeutic settings.
DC.rights	This article is licensed under a Creative Commons Attribution 4.0 International License.
DC.format	102761
citation_title	Altruism Enhances Frontal Alpha Asymmetry and Reduces Sympathetic Activity: A Multimodal EEG-ECG Study With Implications for Therapeutic Interventions
citation_author	Orui, Junya
	Shiraiwa, Keigo
	Inoue, Takao
	Ueda, Masaya
	Ueno, Keita
	Naito, Yasuo
	Ishii, Ryouhei
citation_publisher	John Wiley and Sons Ltd
citation_language	英語
citation_date	2025-08-21
citation_journal_title	Brain and Behavior
citation_volume	15
citation_issue	8
citation_firstpage	e70747
citation_doi	https://doi.org/10.1002/brb3.70747
citation_public_url	https://hdl.handle.net/11094/102761

Altruism Enhances Frontal Alpha Asymmetry and Reduces Sympathetic Activity: A Multimodal EEG-ECG Study With Implications for Therapeutic Interventions

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