Impact of urinary incontinence on idiopathic normal pressure hydrocephalus: a cross-sectional study with Alzheimer's disease and dementia with Lewy bodies

Kanemoto, Hideki; Suehiro, Takashi; Katakami, Shigeki; Koizumi, Fuyuki; Satake, Yuto; Taomoto, Daiki; Takeda, Kayo; Kobayashi, Matasaburo; Yoshiyama, Kenji; Ikeda, Manabu

doi:https://doi.org/10.1111/ggi.70208

Impact of urinary incontinence on idiopathic normal pressure hydrocephalus: a cross-sectional study with Alzheimer's disease and dementia with Lewy bodies

Kanemoto, Hideki; Suehiro, Takashi; Katakami, Shigeki et al.

Geriatrics and Gerontology International, 2025, 25(11), 1463-1675

アクセス数:451件（2026-02-15 18:01 集計）

固定URL: https://hdl.handle.net/11094/102997

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タイトル	Impact of urinary incontinence on idiopathic normal pressure hydrocephalus: a cross-sectional study with Alzheimer's disease and dementia with Lewy bodies
著者	NRID 1000020838932 1000020838932 ORCID 0000-0003-3662-1469 0000-0003-3662-1469 researchmap permalink hkane_gerpsy hkane_gerpsy Scopus Author ID 56521238700 56521238700 著者名 Kanemoto, Hideki
	NRID 1000030866611 1000030866611 researchmap permalink suehiro-takashi suehiro-takashi Scopus Author ID 57190874433 57190874433 著者名 Suehiro, Takashi
	著者名 Katakami, Shigeki
	ORCID 0000-0002-4371-9256 0000-0002-4371-9256 researchmap permalink fuyukikoizumi fuyukikoizumi Scopus Author ID 57328518600 57328518600 著者名 Koizumi, Fuyuki
	ORCID 0000-0002-9350-3162 0000-0002-9350-3162 researchmap permalink y.satake y.satake Scopus Author ID 57218214023 57218214023 著者名 Satake, Yuto
	NRID 1000060906725 1000060906725 ORCID 0009-0006-0578-2517 0009-0006-0578-2517 researchmap permalink taomotodaiki taomotodaiki Scopus Author ID 57328426900 57328426900 著者名 Taomoto, Daiki
	著者名 Takeda, Kayo
	著者名 Kobayashi, Matasaburo
	NRID 1000020426498 1000020426498 ORCID 0009-0008-4353-8632 0009-0008-4353-8632 researchmap permalink kenyoshiyama kenyoshiyama Scopus Author ID 55758733500 55758733500 著者名 Yoshiyama, Kenji
	NRID 1000060284395 1000060284395 researchmap permalink manabu_ikeda manabu_ikeda Scopus Author ID 7404692889 7404692889 著者名 Ikeda, Manabu
キーワード等	Alzheimer's disease
	apathy
	dementia with Lewy bodies
	idiopathic normal pressure hydrocephalus
	urinary incontinence
内容	This is the peer reviewed version of the following article: Kanemoto H., Suehiro T., Katakami S., et al. Impact of Urinary Incontinence on Idiopathic Normal Pressure Hydrocephalus: A Cross-Sectional Study With Alzheimer's Disease and Dementia With Lewy Bodies. Geriatrics and Gerontology International 25(11), 1463 (2025), which has been published in final form at https://doi.org/10.1111/ggi.70208. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
抄録	Aim: This study investigated the impact of urinary incontinence on idiopathic normal pressure hydrocephalus (iNPH) by comparing its characteristics with those of Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). Methods: Cognitive impairment, neuropsychiatric symptoms, activities of daily living (ADL), and caregiver burden were compared using data from 107 patients with iNPH, 610 with AD, and 152 with DLB treated at the outpatient clinic of the Department of Psychiatry at the University of Osaka Hospital, through the chi-square and Kruskal–Wallis tests. Multiple regression analysis was performed to investigate factors related to dementia severity and caregiver burden in patients with iNPH. Results: The iNPH group had milder cognitive impairment and neuropsychiatric symptoms, except for apathy, than the other two groups but showed more dependence on ADL. Patients with iNPH did not differ significantly from those in the other two groups in terms of dementia severity. The caregiver burden was milder in the iNPH group than in the DLB group. In the iNPH group, dementia severity was related to the Mini-Mental State Examination score, urinary incontinence frequency, and apathy, whereas caregiver burden was related to apathy and irritability. Sex, age, and the Timed Up and Go test results were not related to any of these. Conclusions: Compared to AD and DLB, iNPH was characterized by urinary incontinence. Although urinary incontinence has not been extensively studied and treated, it may affect daily life more than gait disturbances and cognitive impairments in patients with iNPH.
出版者	John Wiley and Sons Inc
収録物名	Geriatrics and Gerontology International
巻(号)	25(11)
ページ	1463-1675
刊行年月	2025-10-08
言語	英語
ハンドルURL	https://hdl.handle.net/11094/102997
PISSN	14441586
eISSN	14470594
関連情報 (isVersionOf)	DOI (出版社版) https://doi.org/10.1111/ggi.70208
アクセス権	embargoed access
権利情報	© 2025 Japan Geriatrics Society.
権利情報	The full-text file will be made open to the public on 8 October 2026 in accordance with the publisher's policy.
出版タイプ	Accepted Manuscript
カテゴリ	学術雑誌論文 Journal Article

資源タイプ	学術雑誌論文
ローカル資源タイプ	学術雑誌論文
DCMI資源タイプ	text
DCTERMS.bibliographicCitation	Geriatrics and Gerontology International. 2025, 25(11), p. 1463-1675
DC.title	Impact of urinary incontinence on idiopathic normal pressure hydrocephalus: a cross-sectional study with Alzheimer's disease and dementia with Lewy bodies
DC.creator	Kanemoto, Hideki
	Suehiro, Takashi
	Katakami, Shigeki
	Koizumi, Fuyuki
	Satake, Yuto
	Taomoto, Daiki
	Takeda, Kayo
	Kobayashi, Matasaburo
	Yoshiyama, Kenji
	Ikeda, Manabu
DC.publisher	John Wiley and Sons Inc
DC.language' scheme='DCTERMS.RFC1766	英語
DC.type' scheme='DCTERMS.DCMIType	text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2025-10-08
DC.identifier	https://doi.org/10.1111/ggi.70208
DC.subject	Alzheimer's disease
	apathy
	dementia with Lewy bodies
	idiopathic normal pressure hydrocephalus
	urinary incontinence
DC.description	This is the peer reviewed version of the following article: Kanemoto H., Suehiro T., Katakami S., et al. Impact of Urinary Incontinence on Idiopathic Normal Pressure Hydrocephalus: A Cross-Sectional Study With Alzheimer's Disease and Dementia With Lewy Bodies. Geriatrics and Gerontology International 25(11), 1463 (2025), which has been published in final form at https://doi.org/10.1111/ggi.70208. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
DCTERMS.abstract	Aim: This study investigated the impact of urinary incontinence on idiopathic normal pressure hydrocephalus (iNPH) by comparing its characteristics with those of Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). Methods: Cognitive impairment, neuropsychiatric symptoms, activities of daily living (ADL), and caregiver burden were compared using data from 107 patients with iNPH, 610 with AD, and 152 with DLB treated at the outpatient clinic of the Department of Psychiatry at the University of Osaka Hospital, through the chi-square and Kruskal–Wallis tests. Multiple regression analysis was performed to investigate factors related to dementia severity and caregiver burden in patients with iNPH. Results: The iNPH group had milder cognitive impairment and neuropsychiatric symptoms, except for apathy, than the other two groups but showed more dependence on ADL. Patients with iNPH did not differ significantly from those in the other two groups in terms of dementia severity. The caregiver burden was milder in the iNPH group than in the DLB group. In the iNPH group, dementia severity was related to the Mini-Mental State Examination score, urinary incontinence frequency, and apathy, whereas caregiver burden was related to apathy and irritability. Sex, age, and the Timed Up and Go test results were not related to any of these. Conclusions: Compared to AD and DLB, iNPH was characterized by urinary incontinence. Although urinary incontinence has not been extensively studied and treated, it may affect daily life more than gait disturbances and cognitive impairments in patients with iNPH.
DC.rights	© 2025 Japan Geriatrics Society.
DC.rights	The full-text file will be made open to the public on 8 October 2026 in accordance with the publisher's policy.
DC.format	102997
citation_title	Impact of urinary incontinence on idiopathic normal pressure hydrocephalus: a cross-sectional study with Alzheimer's disease and dementia with Lewy bodies
citation_author	Kanemoto, Hideki
	Suehiro, Takashi
	Katakami, Shigeki
	Koizumi, Fuyuki
	Satake, Yuto
	Taomoto, Daiki
	Takeda, Kayo
	Kobayashi, Matasaburo
	Yoshiyama, Kenji
	Ikeda, Manabu
citation_publisher	John Wiley and Sons Inc
citation_language	英語
citation_date	2025-10-08
citation_journal_title	Geriatrics and Gerontology International
citation_volume	25
citation_issue	11
citation_firstpage	1463
citation_lastpage	1675
citation_doi	https://doi.org/10.1111/ggi.70208
citation_public_url	https://hdl.handle.net/11094/102997

Impact of urinary incontinence on idiopathic normal pressure hydrocephalus: a cross-sectional study with Alzheimer's disease and dementia with Lewy bodies

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