Chitosan/acetoacetylated poly(vinyl alcohol) nanofibers incorporating starch-derived carbon quantum dots with pH-responsive color change for wound dressings

Yao, Ying; Hsu, Yu I.; Sonntag, Selina et al.

Carbohydrate Polymers, 2025, 371, 124477

アクセス数:191件（2026-02-15 22:54 集計）

固定URL: https://hdl.handle.net/11094/103290

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タイトル
Chitosan/acetoacetylated poly(vinyl alcohol) nanofibers incorporating starch-derived carbon quantum dots with pH-responsive color change for wound dressings
著者
著者名
Yao, Ying
NRID
1000010757678 1000010757678
ORCID
0000-0002-4533-7200 0000-0002-4533-7200
researchmap permalink
yuihsu yuihsu
Scopus Author ID
55389981500 55389981500
著者名
Hsu, Yu I.
著者名
Sonntag, Selina
著者名
Fernández-Colino, Alicia
著者名
Jockenhövel, Stefan
NRID
1000070203594 1000070203594
ORCID
0000-0002-8587-2507 0000-0002-8587-2507
researchmap permalink
read0168389 read0168389
Scopus Author ID
7102108908 7102108908
著者名
Uyama, Hiroshi
キーワード等
Carbon quantum dots
Chronic wound care
Electrospun biopolymer nanofibers
High-stability nanofibers
pH-responsive smart materials
内容
Yao Y., Hsu Y.I., Sonntag S., et al. Chitosan/acetoacetylated poly(vinyl alcohol) nanofibers incorporating starch-derived carbon quantum dots with pH-responsive color change for wound dressings. Carbohydrate Polymers 371, 124477 (2026); https://doi.org/10.1016/j.carbpol.2025.124477.
抄録
Monitoring wound healing status through pH-responsive visual cues is essential for the effective management of chronic wounds. In this study, we developed biomass-derived carbon quantum dots (CQDs) using hydroxypropyl starch as the carbon source via a simple, eco-friendly synthesis strategy. Composite nanofibrous dressings were subsequently fabricated by incorporating CQDs with acetoacetylated polyvinyl alcohol (AAPVA) and chitosan (CS) through electrospinning. The resulting CQDs/CS/AAPVA nanofibers exhibited pronounced optical responsiveness within the pH range of 5–8, displaying visible color and fluorescence changes under visible and ultraviolet light. Furthermore, quantitative pH detection was achieved through RGB image analysis, demonstrating strong practical potential for wound monitoring. Owing to the synergistic effects between CQDs and CS, the composite nanofibers also exhibited excellent mechanical strength (Tensile stress = 10.0 ± 1.2 MPa), high swelling capacity (∼ 619.4 ± 26.8 %), structural stability, and biocompatibility, underscoring their significant promise for intelligent chronic wound management and remote monitoring.
出版者
Elsevier Ltd
収録物名
Carbohydrate Polymers
巻(号)
371
ページ
124477
刊行年月
2025-10-07
言語
英語
ハンドルURL
https://hdl.handle.net/11094/103290
PISSN
01448617
関連情報 (isIdenticalTo)
DOI (出版社版)
https://doi.org/10.1016/j.carbpol.2025.124477
アクセス権
open access
権利情報
This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
出版タイプ
Version of Record
カテゴリ
学術雑誌論文 Journal Article