Development of dentition: From initiation to occlusion and related diseases

Kurosaka, Hiroshi; Itoh, Shinsuke; Morita, Chisato; Tsujimoto, Takayuki; Murata, Yuka; Inubushi, Toshihiro; Yamashiro, Takashi

doi:https://doi.org/10.1016/j.job.2022.02.005

Development of dentition: From initiation to occlusion and related diseases

Kurosaka, Hiroshi; Itoh, Shinsuke; Morita, Chisato et al.

Journal of Oral Biosciences, 2022, 64(2), 159-164

アクセス数:87件（2026-02-16 10:17 集計）

固定URL: https://hdl.handle.net/11094/103594

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タイトル	Development of dentition: From initiation to occlusion and related diseases
著者	NRID 1000020509369 1000020509369 ORCID 0000-0002-8956-5467 0000-0002-8956-5467 researchmap permalink kurosakahiroshi kurosakahiroshi Scopus Author ID 11839162500 11839162500 著者名 Kurosaka, Hiroshi
	NRID 1000040633706 1000040633706 ORCID 0000-0001-9567-8188 0000-0001-9567-8188 researchmap permalink read12006 read12006 Scopus Author ID 55633677700 55633677700 著者名 Itoh, Shinsuke
	NRID 1000050754727 1000050754727 researchmap permalink c_morita c_morita Scopus Author ID 56310853500 56310853500 著者名 Morita, Chisato
	NRID 1000070984904 1000070984904 Scopus Author ID 57410081900 57410081900 著者名 Tsujimoto, Takayuki
	NRID 1000090755068 1000090755068 ORCID 0000-0002-7072-849X 0000-0002-7072-849X researchmap permalink yukamurata yukamurata Scopus Author ID 55813110200 55813110200 著者名 Murata, Yuka
	NRID 1000030550941 1000030550941 ORCID 0000-0001-5303-4763 0000-0001-5303-4763 researchmap permalink opathone0141 opathone0141 Scopus Author ID 23097933700 23097933700 著者名 Inubushi, Toshihiro
	NRID 1000070294428 1000070294428 ORCID 0000-0002-4419-9643 0000-0002-4419-9643 researchmap permalink read0051793 read0051793 Scopus Author ID 55416765600 55416765600 著者名 Yamashiro, Takashi
キーワード等	Craniofacial abnormalities
	Primary failure of eruption
	Tooth agenesis
	Tooth development
	Tooth eruption
内容	Kurosaka H., Itoh S., Morita C., et al. Development of dentition: From initiation to occlusion and related diseases. Journal of Oral Biosciences 64, 159 (2022); https://doi.org/10.1016/j.job.2022.02.005.
抄録	Background: The development of dentition begins in the embryonic oral cavity and progresses in the branchial arches and alveolar bone. Continuous cellular and molecular crosstalk occurs during crown formation, after which the tooth germ begins to migrate apically through the alveolar process into the oral cavity. It eventually comes in contact with its antagonist in the contralateral jaw to establish functional occlusion. Any defect in either step can result in delayed tooth development, the spectrum of which varies from a congenitally missing tooth to an impacted tooth (infraocclusion) with an eruption problem, both of which can impair oral function. Highlight: Congenitally missing teeth or eruption problems may result from genetic mutations. Several different mutations have been identified, each causing a distinct phenotype. Thus, it is imperative that medical providers understand the fundamentals of these genetic principles that govern such dental diseases. Conclusion: In this review, we focus on several diseases, including congenitally missing teeth and tooth eruption problems. We review these diseases with aspect to their association with a particular syndrome, as well as independently in a non-syndromic capacity. We also review previously identified genetic mutations and discuss the possible mechanisms that cause individual phenotypes by analyzing previous investigations. We also discuss future prospects of how genetic diagnosis and precision medicine could impact the clinical environment in the field of dentistry. Ethical approval: Present study has been carried out in accordance with The Code of Ethics of the World Medical Association and approved by Institutional Review Board of Osaka University Graduate School of Dentistry.
出版者	Japanese Association for Oral Biology
収録物名	Journal of Oral Biosciences
巻(号)	64(2)
ページ	159-164
刊行年月	2022-05-18
言語	英語
ハンドルURL	https://hdl.handle.net/11094/103594
PISSN	13490079
eISSN	18803865
関連情報 (isVersionOf)	DOI (出版社版) https://doi.org/10.1016/j.job.2022.02.005
アクセス権	open access
権利情報	© 2022. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
出版タイプ	Accepted Manuscript
カテゴリ	学術雑誌論文 Journal Article

資源タイプ	学術雑誌論文
ローカル資源タイプ	学術雑誌論文
DCMI資源タイプ	text
DCTERMS.bibliographicCitation	Journal of Oral Biosciences. 2022, 64(2), p. 159-164
DC.title	Development of dentition: From initiation to occlusion and related diseases
DC.creator	Kurosaka, Hiroshi
	Itoh, Shinsuke
	Morita, Chisato
	Tsujimoto, Takayuki
	Murata, Yuka
	Inubushi, Toshihiro
	Yamashiro, Takashi
DC.publisher	Japanese Association for Oral Biology
DC.language' scheme='DCTERMS.RFC1766	英語
DC.type' scheme='DCTERMS.DCMIType	text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2022-05-18
DC.identifier	https://doi.org/10.1016/j.job.2022.02.005
DC.subject	Craniofacial abnormalities
	Primary failure of eruption
	Tooth agenesis
	Tooth development
	Tooth eruption
DC.description	Kurosaka H., Itoh S., Morita C., et al. Development of dentition: From initiation to occlusion and related diseases. Journal of Oral Biosciences 64, 159 (2022); https://doi.org/10.1016/j.job.2022.02.005.
DCTERMS.abstract	Background: The development of dentition begins in the embryonic oral cavity and progresses in the branchial arches and alveolar bone. Continuous cellular and molecular crosstalk occurs during crown formation, after which the tooth germ begins to migrate apically through the alveolar process into the oral cavity. It eventually comes in contact with its antagonist in the contralateral jaw to establish functional occlusion. Any defect in either step can result in delayed tooth development, the spectrum of which varies from a congenitally missing tooth to an impacted tooth (infraocclusion) with an eruption problem, both of which can impair oral function. Highlight: Congenitally missing teeth or eruption problems may result from genetic mutations. Several different mutations have been identified, each causing a distinct phenotype. Thus, it is imperative that medical providers understand the fundamentals of these genetic principles that govern such dental diseases. Conclusion: In this review, we focus on several diseases, including congenitally missing teeth and tooth eruption problems. We review these diseases with aspect to their association with a particular syndrome, as well as independently in a non-syndromic capacity. We also review previously identified genetic mutations and discuss the possible mechanisms that cause individual phenotypes by analyzing previous investigations. We also discuss future prospects of how genetic diagnosis and precision medicine could impact the clinical environment in the field of dentistry. Ethical approval: Present study has been carried out in accordance with The Code of Ethics of the World Medical Association and approved by Institutional Review Board of Osaka University Graduate School of Dentistry.
DC.rights	© 2022. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
DC.format	103594
citation_title	Development of dentition: From initiation to occlusion and related diseases
citation_author	Kurosaka, Hiroshi
	Itoh, Shinsuke
	Morita, Chisato
	Tsujimoto, Takayuki
	Murata, Yuka
	Inubushi, Toshihiro
	Yamashiro, Takashi
citation_publisher	Japanese Association for Oral Biology
citation_language	英語
citation_date	2022-05-18
citation_journal_title	Journal of Oral Biosciences
citation_volume	64
citation_issue	2
citation_firstpage	159
citation_lastpage	164
citation_doi	https://doi.org/10.1016/j.job.2022.02.005
citation_public_url	https://hdl.handle.net/11094/103594

Development of dentition: From initiation to occlusion and related diseases

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