Difference Between Low-Speed and High-Speed Rotational Atherectomy Using Two Types of Guidewires

Kawamura, Akito; Okayama, Keita; Nohara, Hiroaki; Nakano, Tomoaki; Sakata, Yasushi

doi:https://doi.org/10.1002/ccd.70514

Difference Between Low-Speed and High-Speed Rotational Atherectomy Using Two Types of Guidewires

Kawamura, Akito; Okayama, Keita; Nohara, Hiroaki et al.

Catheterization and Cardiovascular Interventions, 2026

アクセス数:23件（2026-05-02 02:38 集計）

固定URL: https://hdl.handle.net/11094/104262

閲覧可能ファイル

ファイル	フォーマット	利用条件	サイズ	閲覧回数	利用開始日	説明	information
CatheterCardiovascInterventions_70514	pdf	なし	2.64 MB	18	2026.03.31

Creative Commons : 表示 - 非営利

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

タイトル	Difference Between Low-Speed and High-Speed Rotational Atherectomy Using Two Types of Guidewires
著者	著者名 Kawamura, Akito
	NRID 1000050705168 1000050705168 researchmap permalink oky oky Scopus Author ID 35181800600 35181800600 著者名 Okayama, Keita
	著者名 Nohara, Hiroaki
	NRID 1000090723180 1000090723180 ORCID 0009-0008-4991-0087 0009-0008-4991-0087 researchmap permalink tomoaki85927 tomoaki85927 Scopus Author ID 57218381901 57218381901 著者名 Nakano, Tomoaki
	NRID 1000000397671 1000000397671 ORCID 0000-0002-5618-4721 0000-0002-5618-4721 researchmap permalink C4589 C4589 Scopus Author ID 35395964700 35395964700 著者名 Sakata, Yasushi
キーワード等	in vivo experimental study
	optical coherence tomography
	rotational atherectomy
	severe calcified lesion
内容	Kawamura A., Okayama K., Nohara H., et al. Difference Between Low-Speed and High-Speed Rotational Atherectomy Using Two Types of Guidewires. Catheterization and Cardiovascular Interventions (2026); https://doi.org/10.1002/ccd.70514.
抄録	Background: Debulking devices are necessary to treat severe calcified lesions. Rotational atherectomy (RA) is widely employed to modify calcified plaques, but the influence of procedural variables, such as guidewire type and ablation speed, on ablation outcomes is not well established. Aims: This study aimed to evaluate the effect of guidewire type and rotational speed on ablation performance during RA using an in vitro simulation system using HEARTROID system® and optical coherence tomography (OCT). Methods: Using the HEARTROID® cardiac simulator, twenty calcified lesions in a mid-left anterior descending (LAD) artery model were ablated. Two types of RotaWire-floppy and extra-support-were tested at high (190,000 rpm) and low (140,000 rpm) speeds. Pre- and post-ablation OCT were performed to evaluate lumen area, directional discrepancy between pre-OCT or guidewire position and actual ablation direction, and the size of debulked regions. Results: A total of 171 debulked cross-sections were analyzed. In floppy wire groups, high-speed RA was associated with significantly greater directional discrepancy compared to low-speed RA. Conversely, in extra-support wire groups, high-speed RA resulted in significantly smaller directional discrepancy than low-speed RA. Debulked area tended to be larger at low speed for floppy wire and at high speed for extra-support wire, though differences were not statistically significant. The combination of extra-support wire and high-speed ablation produced the most predictable and controlled debulking. Conclusions: Guidewire type and rotational speed significantly influence directional control during RA. High-speed ablation with an extra-support wire minimizes directional discrepancy and may allow more predictable and controlled lesion modification.
出版者	John Wiley and Sons Inc
収録物名	Catheterization and Cardiovascular Interventions
刊行年月	2026-02-09
言語	英語
ハンドルURL	https://hdl.handle.net/11094/104262
PISSN	15221946
eISSN	1522726X
関連情報 (isIdenticalTo)	DOI (出版社版) https://doi.org/10.1002/ccd.70514
アクセス権	open access
権利情報	This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
出版タイプ	Version of Record
カテゴリ	学術雑誌論文 Journal Article

資源タイプ	学術雑誌論文
ローカル資源タイプ	学術雑誌論文
DCMI資源タイプ	text
DCTERMS.bibliographicCitation	Catheterization and Cardiovascular Interventions. 2026
DC.title	Difference Between Low-Speed and High-Speed Rotational Atherectomy Using Two Types of Guidewires
DC.creator	Kawamura, Akito
	Okayama, Keita
	Nohara, Hiroaki
	Nakano, Tomoaki
	Sakata, Yasushi
DC.publisher	John Wiley and Sons Inc
DC.language' scheme='DCTERMS.RFC1766	英語
DC.type' scheme='DCTERMS.DCMIType	text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2026-02-09
DC.identifier	https://doi.org/10.1002/ccd.70514
DC.subject	in vivo experimental study
	optical coherence tomography
	rotational atherectomy
	severe calcified lesion
DC.description	Kawamura A., Okayama K., Nohara H., et al. Difference Between Low-Speed and High-Speed Rotational Atherectomy Using Two Types of Guidewires. Catheterization and Cardiovascular Interventions (2026); https://doi.org/10.1002/ccd.70514.
DCTERMS.abstract	Background: Debulking devices are necessary to treat severe calcified lesions. Rotational atherectomy (RA) is widely employed to modify calcified plaques, but the influence of procedural variables, such as guidewire type and ablation speed, on ablation outcomes is not well established. Aims: This study aimed to evaluate the effect of guidewire type and rotational speed on ablation performance during RA using an in vitro simulation system using HEARTROID system® and optical coherence tomography (OCT). Methods: Using the HEARTROID® cardiac simulator, twenty calcified lesions in a mid-left anterior descending (LAD) artery model were ablated. Two types of RotaWire-floppy and extra-support-were tested at high (190,000 rpm) and low (140,000 rpm) speeds. Pre- and post-ablation OCT were performed to evaluate lumen area, directional discrepancy between pre-OCT or guidewire position and actual ablation direction, and the size of debulked regions. Results: A total of 171 debulked cross-sections were analyzed. In floppy wire groups, high-speed RA was associated with significantly greater directional discrepancy compared to low-speed RA. Conversely, in extra-support wire groups, high-speed RA resulted in significantly smaller directional discrepancy than low-speed RA. Debulked area tended to be larger at low speed for floppy wire and at high speed for extra-support wire, though differences were not statistically significant. The combination of extra-support wire and high-speed ablation produced the most predictable and controlled debulking. Conclusions: Guidewire type and rotational speed significantly influence directional control during RA. High-speed ablation with an extra-support wire minimizes directional discrepancy and may allow more predictable and controlled lesion modification.
DC.rights	This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
DC.format	104262
citation_title	Difference Between Low-Speed and High-Speed Rotational Atherectomy Using Two Types of Guidewires
citation_author	Kawamura, Akito
	Okayama, Keita
	Nohara, Hiroaki
	Nakano, Tomoaki
	Sakata, Yasushi
citation_publisher	John Wiley and Sons Inc
citation_language	英語
citation_date	2026-02-09
citation_journal_title	Catheterization and Cardiovascular Interventions
citation_doi	https://doi.org/10.1002/ccd.70514
citation_public_url	https://hdl.handle.net/11094/104262

Difference Between Low-Speed and High-Speed Rotational Atherectomy Using Two Types of Guidewires

閲覧可能ファイル

論文情報

論文詳細を表示