Effects of multiple tongue conditions on the diversity and composition of the oral microbiota

Hamada, Masakazu; Matsuoka, Yuriko; Ogaya, Yuko; Kadota, Tamami; Ikeda, Shunya; Akitomo, Tatsuya; Nomura, Ryota; Nakano, Kazuhiko

doi:https://doi.org/10.1080/20002297.2026.2684141

Effects of multiple tongue conditions on the diversity and composition of the oral microbiota

Hamada, Masakazu; Matsuoka, Yuriko; Ogaya, Yuko et al.

Journal of Oral Microbiology, 2026, 18(1), 2684141

アクセス数:162件（2026-09-08 10:14 集計）

固定URL: https://hdl.handle.net/11094/106069

閲覧可能ファイル

ファイル	フォーマット	利用条件	サイズ	閲覧回数	利用開始日	説明	information
JOralMicrobiol_18_1_2684141	pdf	なし	3.59 MB	19	2026.08.07

Creative Commons : 表示 - 非営利

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

タイトル	Effects of multiple tongue conditions on the diversity and composition of the oral microbiota
著者	NRID 1000080506361 1000080506361 researchmap permalink 6361 6361 Scopus Author ID 36616148000 36616148000 著者名 Hamada, Masakazu
	NRID 1000070865790 1000070865790 著者名 Matsuoka, Yuriko
	NRID 1000040803078 1000040803078 researchmap permalink y_ogaya y_ogaya Scopus Author ID 56460237100 56460237100 著者名 Ogaya, Yuko
	NRID 1000010908643 1000010908643 ORCID 0009-0007-6613-0093 0009-0007-6613-0093 researchmap permalink kadota-tamami kadota-tamami Scopus Author ID 57204146709 57204146709 著者名 Kadota, Tamami
	著者名 Ikeda, Shunya
	NRID 1000090909681 1000090909681 著者名 Akitomo, Tatsuya
	NRID 1000090437385 1000090437385 著者名 Nomura, Ryota
	NRID 1000000379083 1000000379083 ORCID 0000-0002-2209-2685 0000-0002-2209-2685 researchmap permalink read0202427 read0202427 Scopus Author ID 7402011667 7402011667 著者名 Nakano, Kazuhiko
キーワード等	fissured tongue
	oral cavity
	oral microbiome
	saliva
	tongue coating
	Tongue condition
内容	Hamada M., Matsuoka Y., Ogaya Y., et al. Effects of multiple tongue conditions on the diversity and composition of the oral microbiota. Journal of Oral Microbiology 18, 2684141 (2026); https://doi.org/10.1080/20002297.2026.2684141.
抄録	Objective: The present study examined the effects of multiple tongue conditions on the diversity and composition of the oral microbiota to obtain a more detailed understanding of their potential role in health and disease. Method: Ninety-three subjects were classified according to tongue conditions, such as a yellow tongue coating, the presence or absence of swelling of the sublingual vein, a red tongue or red tongue tip, a fissured tongue, enlarged tongue, geographic tongue, and tooth marks. The oral microbiota was examined using α- and β-diversity metrics and taxonomic composition analyses. Results: α-Diversity was significantly lower in subjects with a fissured tongue than in those without. A β-diversity analysis revealed distinct microbial community structures between these subjects. Taxonomic profiling showed a higher abundance of Firmicutes and sulfur-metabolizing bacteria in subjects with a fissured tongue. However, these differences were not retained after age adjustment. Age-restricted sensitivity analyses identified age-independent microbial signatures associated with a fissured tongue, including a reduced abundance of Veillonella and Granulicatella in saliva samples. Conclusion: Morphological abnormalities of the tongue are associated with distinct oral microbiome profiles. These features may reflect oral microbial dysbiosis and could be relevant for future studies exploring non-invasive markers of oral health.
出版者	Taylor and Francis Ltd.
収録物名	Journal of Oral Microbiology
巻(号)	18(1)
ページ	2684141
刊行年月	2026-06-07
言語	英語
ハンドルURL	https://hdl.handle.net/11094/106069
eISSN	20002297
関連情報 (isIdenticalTo)	DOI (出版社版) https://doi.org/10.1080/20002297.2026.2684141
アクセス権	open access
権利情報	This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
出版タイプ	Version of Record
カテゴリ	学術雑誌論文 Journal Article

資源タイプ	学術雑誌論文
ローカル資源タイプ	学術雑誌論文
DCMI資源タイプ	text
DCTERMS.bibliographicCitation	Journal of Oral Microbiology. 2026, 18(1), p. 2684141
DC.title	Effects of multiple tongue conditions on the diversity and composition of the oral microbiota
DC.creator	Hamada, Masakazu
	Matsuoka, Yuriko
	Ogaya, Yuko
	Kadota, Tamami
	Ikeda, Shunya
	Akitomo, Tatsuya
	Nomura, Ryota
	Nakano, Kazuhiko
DC.publisher	Taylor and Francis Ltd.
DC.language' scheme='DCTERMS.RFC1766	英語
DC.type' scheme='DCTERMS.DCMIType	text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2026-06-07
DC.identifier	https://doi.org/10.1080/20002297.2026.2684141
DC.subject	fissured tongue
	oral cavity
	oral microbiome
	saliva
	tongue coating
	Tongue condition
DC.description	Hamada M., Matsuoka Y., Ogaya Y., et al. Effects of multiple tongue conditions on the diversity and composition of the oral microbiota. Journal of Oral Microbiology 18, 2684141 (2026); https://doi.org/10.1080/20002297.2026.2684141.
DCTERMS.abstract	Objective: The present study examined the effects of multiple tongue conditions on the diversity and composition of the oral microbiota to obtain a more detailed understanding of their potential role in health and disease. Method: Ninety-three subjects were classified according to tongue conditions, such as a yellow tongue coating, the presence or absence of swelling of the sublingual vein, a red tongue or red tongue tip, a fissured tongue, enlarged tongue, geographic tongue, and tooth marks. The oral microbiota was examined using α- and β-diversity metrics and taxonomic composition analyses. Results: α-Diversity was significantly lower in subjects with a fissured tongue than in those without. A β-diversity analysis revealed distinct microbial community structures between these subjects. Taxonomic profiling showed a higher abundance of Firmicutes and sulfur-metabolizing bacteria in subjects with a fissured tongue. However, these differences were not retained after age adjustment. Age-restricted sensitivity analyses identified age-independent microbial signatures associated with a fissured tongue, including a reduced abundance of Veillonella and Granulicatella in saliva samples. Conclusion: Morphological abnormalities of the tongue are associated with distinct oral microbiome profiles. These features may reflect oral microbial dysbiosis and could be relevant for future studies exploring non-invasive markers of oral health.
DC.rights	This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
DC.format	106069
citation_title	Effects of multiple tongue conditions on the diversity and composition of the oral microbiota
citation_author	Hamada, Masakazu
	Matsuoka, Yuriko
	Ogaya, Yuko
	Kadota, Tamami
	Ikeda, Shunya
	Akitomo, Tatsuya
	Nomura, Ryota
	Nakano, Kazuhiko
citation_publisher	Taylor and Francis Ltd.
citation_language	英語
citation_date	2026-06-07
citation_journal_title	Journal of Oral Microbiology
citation_volume	18
citation_issue	1
citation_firstpage	2684141
citation_doi	https://doi.org/10.1080/20002297.2026.2684141
citation_public_url	https://hdl.handle.net/11094/106069

Effects of multiple tongue conditions on the diversity and composition of the oral microbiota

閲覧可能ファイル

論文情報

論文詳細を表示