From Flower Micelles to Flower Necklaces: Self-Assembly of Dodecyl Succinate−Modified Pullulan in Aqueous Solution

Matsumoto, Yuki; Kitamura, Shinichi; Takahashi, Rintaro et al.

Biomacromolecules, 2026

アクセス数:116件（2026-11-03 10:32 集計）

固定URL: https://hdl.handle.net/11094/106884

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論文情報

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タイトル
From Flower Micelles to Flower Necklaces: Self-Assembly of Dodecyl Succinate−Modified Pullulan in Aqueous Solution
著者
著者名
Matsumoto, Yuki
NRID
1000060117869 1000060117869
著者名
Kitamura, Shinichi
NRID
1000010794125 1000010794125
ORCID
0000-0003-2168-9436 0000-0003-2168-9436
researchmap permalink
takahashirintaro takahashirintaro
Scopus Author ID
7401848988 7401848988
著者名
Takahashi, Rintaro
NRID
1000060334132 1000060334132
ORCID
0000-0001-7363-4491 0000-0001-7363-4491
researchmap permalink
kenterao kenterao
Scopus Author ID
7101653015 7101653015
著者名
Terao, Ken
キーワード等
pullulan
amphiphilic polysaccharide
flower micelle
flower-necklace micelle
small-angle X-ray scattering
polymer self-assembly
内容
Matsumoto Yuki, Kitamura Shinichi, Takahashi Rintaro, et al. From Flower Micelles to Flower Necklaces: Self-Assembly of Dodecyl Succinate−Modified Pullulan in Aqueous Solution. Biomacromolecules (2026).
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Biomacromolecules, © 2026. To access the final published article, see https://doi.org/10.1021/acs.biomac.6c01274
抄録
Fourteen pullulan derivatives bearing dodecyl succinate side chains (PulDDS) were synthesized from seven parent pullulan samples covering wide ranges of weight-average molar mass (Mw) and degree of substitution (DS). Their micellar structures in 25 mM aqueous NaCl were characterized by SEC-MALS, light scattering, small-angle X-ray scattering (SAXS), transmission electron microscopy, and fluorescence measurements. Analysis using flower and flower-necklace models showed that low-Mw PulDDS formed unicore flower micelles, whereas high-Mw PulDDS formed multicore flower-necklace micelles. While unicore flower micelles have been reported for amphiphilic synthetic copolymers, such micelles have been much less explored for amphiphilic polysaccharide derivatives in aqueous media; here we provide a quantitative characterization based on combined scattering and fluorescence measurements. Although water is a good solvent for pullulan, low-DS samples exhibited negative second virial coefficients (A₂), indicating attractive interchain interactions and no well-defined micellar structure. In contrast, high-DS samples showed positive A₂ values and pronounced micellar SAXS features, consistent with repulsive interactions between looped chains.
出版者
American Chemical Society (ACS)
収録物名
Biomacromolecules
刊行年月
2026-10-07
言語
英語
ハンドルURL
https://hdl.handle.net/11094/106884
PISSN
15257797
eISSN
15264602
関連情報 (isVersionOf)
DOI (出版社版)
https://doi.org/10.1021/acs.biomac.6c01274
アクセス権
embargoed access
権利情報
The full-text file will be made open to the public on 7 October 2027 in accordance with the publisher's policy.
出版タイプ
Accepted Manuscript
カテゴリ
学術雑誌論文 Journal Article