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2021-01-18
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https://doi.org/10.1163/156856203322553437
このアイテムへのリンクには次のURLをご利用ください:http://hdl.handle.net/11094/25935
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論文情報
タイトル
Reagent-free crosslinking of aqueous gelatin : manufacture and characteristics of gelatin gels irradiated with gamma-ray and electron beam
著者
Furusawa, Kazuya
Furusawa, Kazuya
Mori, Yasutaka
Mori, Yasutaka
Yoshii, Fumio
Yoshii, Fumio
Terao, Ken
Terao, Ken
Nishida, Hirokazu
Nishida, Hirokazu
Nagasawa, Naotsugu
Nagasawa, Naotsugu
Dobashi, Toshiaki
Dobashi, Toshiaki
キーワード等
hydrogels
gelatin
biodegradability
radiation
electron beam
crosslinking
proteinase
reagent-free
内容
This is an Author's Accepted Manuscript of an article published in include the complete citation information for the final version of the artcle as published in the Journal of Biomaterials Science, Polymer Edition, 2003-11, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1163/156856203322553437
抄録
In order to obtain a gelatin hydrogel crosslinked by a reagent-free method, gamma-ray and electron beam radiation was applied to porcine, bovine and fish gelatin gels and the products were characterized by measuring the gel fraction, the swelling ratio and the enzymatic degradability. On increasing the radiation dose, the gel fraction increased and both the swelling ratio and the enzymatic degradability decreased. The transition temperature from gel to sol of the hydrogel containing more than 5% mammal gelatins increased up to more than 90°C when gamma-ray or electron beam were irradiated by more than 10 kGy. The results show that the degree of crosslinking of irradiated gelatin hydrogels increases with increasing irradiation dose and with decreasing concentration. It is suggested that the radiation crosslinking occurs around the physical crosslinking point or multiple helix structure of gelatin gel.
公開者
Taylor and Francis Inc
掲載誌名
Journal of Biomaterials Science, Polymer Edition
巻
14
号
11
開始ページ
1197
終了ページ
1208
刊行年月
2003-11
ISSN
09205063
NCID
AA10731799
DOI
info:doi/10.1163/156856203322553437
URL
http://hdl.handle.net/11094/25935
言語
英語
カテゴリ
学術雑誌論文 Journal Article
論文詳細を表示
著者版フラグ
author
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学術雑誌論文
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text
DCTERMS.bibliographicCitation
Journal of Biomaterials Science, Polymer Edition.14(11) P.1197-P.1208
DC.title
Reagent-free crosslinking of aqueous gelatin : manufacture and characteristics of gelatin gels irradiated with gamma-ray and electron beam
DC.creator
Furusawa, Kazuya
Mori, Yasutaka
Yoshii, Fumio
Terao, Ken
Nishida, Hirokazu
Nagasawa, Naotsugu
Dobashi, Toshiaki
DC.publisher
Taylor and Francis Inc
DC.language" scheme="DCTERMS.RFC1766
英語
DCTERMS.issued" scheme="DCTERMS.W3CDTF
2003-11
DC.identifier
info:doi/10.1163/156856203322553437
DC.identifier" scheme="DCTERMS.URI
http://hdl.handle.net/11094/25935
DC.subject
hydrogels
gelatin
biodegradability
radiation
electron beam
crosslinking
proteinase
reagent-free
DC.description
This is an Author's Accepted Manuscript of an article published in include the complete citation information for the final version of the artcle as published in the Journal of Biomaterials Science, Polymer Edition, 2003-11, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1163/156856203322553437
DCTERMS.abstract
In order to obtain a gelatin hydrogel crosslinked by a reagent-free method, gamma-ray and electron beam radiation was applied to porcine, bovine and fish gelatin gels and the products were characterized by measuring the gel fraction, the swelling ratio and the enzymatic degradability. On increasing the radiation dose, the gel fraction increased and both the swelling ratio and the enzymatic degradability decreased. The transition temperature from gel to sol of the hydrogel containing more than 5% mammal gelatins increased up to more than 90°C when gamma-ray or electron beam were irradiated by more than 10 kGy. The results show that the degree of crosslinking of irradiated gelatin hydrogels increases with increasing irradiation dose and with decreasing concentration. It is suggested that the radiation crosslinking occurs around the physical crosslinking point or multiple helix structure of gelatin gel.
citation_title
Reagent-free crosslinking of aqueous gelatin : manufacture and characteristics of gelatin gels irradiated with gamma-ray and electron beam
citation_author
Furusawa, Kazuya
Mori, Yasutaka
Yoshii, Fumio
Terao, Ken
Nishida, Hirokazu
Nagasawa, Naotsugu
Dobashi, Toshiaki
citation_publisher
Taylor and Francis Inc
citation_language
英語
citation_date
2003-11
citation_journal_title
Journal of Biomaterials Science, Polymer Edition
citation_volume
14
citation_issue
11
citation_firstpage
1197
citation_lastpage
1208
citation_issn
09205063
citation_doi
info:doi/10.1163/156856203322553437
citation_public_url
http://hdl.handle.net/11094/25935
citation_keywords
hydrogels
gelatin
biodegradability
radiation
electron beam
crosslinking
proteinase
reagent-free