学術雑誌論文

学術雑誌論文

Scientific Reports. 2017, 7, p. 43456

The mechanics clarifying counterclockwise rotation in most IVF eggs in mice

Nature Research

英語

2017-03-03

https://doi.org/10.1038/srep43456

Ishimoto, K., Ikawa, M. & Okabe, M. The mechanics clarifying counterclockwise rotation in most IVF eggs in mice. Sci Rep 7, 43456 (2017). https://doi.org/10.1038/srep43456

In mammalian fertilization, a small spermatozoon interacts with an egg that is a few thousand times larger in volume. In spite of the big difference in size and mass, when spermatozoa are bound to eggs, they begin rotating the eggs in in vitro observation. This was dubbed the 'fertilization dance'. Interestingly, some papers reported that the rotation was counterclockwise, although the reason for this skewed rotation was not clarified. We focused on a chirality of helical beating of spermatozoa and found that eggs rotate counterclockwise in simulations under a certain geometrical condition where the eggs were situated. This theory of egg rotation was validated by demonstrating egg rotation in a clockwise direction by floating eggs to the upper surface of the IVF medium. The enigma of skewed rotation of IVF eggs was clarified.

© 2017 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License.

78581

The mechanics clarifying counterclockwise rotation in most IVF eggs in mice

Nature Research

英語

2017-03-03

Scientific Reports

7

43456

https://doi.org/10.1038/srep43456

28256541

https://hdl.handle.net/11094/78581