Towards single particle imaging of human chromosomes at SACLA

Robinson, Ian; Schwenke, Joerg; Yusuf, Mohammed; Estandarte, Ana; Zhang, Fucai; Chen, Bo; Clark, Jesse; Song, Changyong; Nam, Daewoong; Joti, Yasumasa; Tono, Kensuke; Yabashi, Makina; Ratnasari, Gina; Kaneyoshi, Kohei; Takata, Hideaki; Fukui, Kiichi

doi:https://doi.org/10.1088/0953-4075/48/24/244007

Towards single particle imaging of human chromosomes at SACLA

Robinson, Ian; Schwenke, Joerg; Yusuf, Mohammed et al.

Journal of Physics B: Atomic, Molecular and Optical Physics, 2015, 48(24), 244007

アクセス数:1,153件（2026-04-06 00:21 集計）

固定URL: https://hdl.handle.net/11094/79030

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タイトル	Towards single particle imaging of human chromosomes at SACLA
著者	著者名 Robinson, Ian
	著者名 Schwenke, Joerg
	著者名 Yusuf, Mohammed
	著者名 Estandarte, Ana
	著者名 Zhang, Fucai
	著者名 Chen, Bo
	著者名 Clark, Jesse
	著者名 Song, Changyong
	著者名 Nam, Daewoong
	NRID 1000030360415 1000030360415 著者名 Joti, Yasumasa
	NRID 1000000353508 1000000353508 著者名 Tono, Kensuke
	NRID 1000000372144 1000000372144 著者名 Yabashi, Makina
	著者名 Ratnasari, Gina
	著者名 Kaneyoshi, Kohei
	NRID 1000020455207 1000020455207 著者名 Takata, Hideaki
	NRID 1000000311770 1000000311770 researchmap permalink read0068600 read0068600 著者名 Fukui, Kiichi
キーワード等	chromosome
	radiation damage
	diffraction
	metaphase
	iterative phasing
	coherence
	imaging
内容	Robinson I., Schwenke J., Yusuf M., et al. Towards single particle imaging of human chromosomes at SACLA. Journal of Physics B: Atomic, Molecular and Optical Physics, 48, 24, 244007. https://doi.org/10.1088/0953-4075/48/24/244007.
抄録	Single particle imaging (SPI) is one of the front-page opportunities which were used to motivate the construction of the first x-ray free electron lasers (XFELs). SPI's big advantage is that it avoids radiation damage to biological samples because the diffraction takes place in femtosecond single shots before any atomic motion can take place in the sample, hence before the onset of radiation damage. This is the 'diffract before destruction' theme, destruction being assured from the high x-ray doses used. This article reports our collaboration's first attempt at SPI using the SACLA XFEL facility in June 2015. The report is limited to experience with the instrumentation and examples of data because we have not yet had time to invert them to images.
出版者	Institute of Physics Publishing
収録物名	Journal of Physics B: Atomic, Molecular and Optical Physics
巻(号)	48(24)
ページ	244007
刊行年月	2015-11-03
言語	英語
ハンドルURL	https://hdl.handle.net/11094/79030
PISSN	09534075
eISSN	13616455
NCID	AA10693237
関連情報 (isIdenticalTo)	DOI (出版社版) https://doi.org/10.1088/0953-4075/48/24/244007
アクセス権	open access
権利情報	© 2015 IOP Publishing Ltd. This article is licensed under a Creative Commons Attribution 3.0 Unported License.
出版タイプ	Version of Record
カテゴリ	学術雑誌論文 Journal Article

資源タイプ	学術雑誌論文
ローカル資源タイプ	学術雑誌論文
DCMI資源タイプ	text
DCTERMS.bibliographicCitation	Journal of Physics B: Atomic, Molecular and Optical Physics. 2015, 48(24), p. 244007
DC.title	Towards single particle imaging of human chromosomes at SACLA
DC.creator	Robinson, Ian
	Schwenke, Joerg
	Yusuf, Mohammed
	Estandarte, Ana
	Zhang, Fucai
	Chen, Bo
	Clark, Jesse
	Song, Changyong
	Nam, Daewoong
	Joti, Yasumasa
	Tono, Kensuke
	Yabashi, Makina
	Ratnasari, Gina
	Kaneyoshi, Kohei
	Takata, Hideaki
	Fukui, Kiichi
DC.publisher	Institute of Physics Publishing
DC.language' scheme='DCTERMS.RFC1766	英語
DC.type' scheme='DCTERMS.DCMIType	text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2015-11-03
DC.identifier	https://doi.org/10.1088/0953-4075/48/24/244007
DC.subject	chromosome
	radiation damage
	diffraction
	metaphase
	iterative phasing
	coherence
	imaging
DC.description	Robinson I., Schwenke J., Yusuf M., et al. Towards single particle imaging of human chromosomes at SACLA. Journal of Physics B: Atomic, Molecular and Optical Physics, 48, 24, 244007. https://doi.org/10.1088/0953-4075/48/24/244007.
DCTERMS.abstract	Single particle imaging (SPI) is one of the front-page opportunities which were used to motivate the construction of the first x-ray free electron lasers (XFELs). SPI's big advantage is that it avoids radiation damage to biological samples because the diffraction takes place in femtosecond single shots before any atomic motion can take place in the sample, hence before the onset of radiation damage. This is the 'diffract before destruction' theme, destruction being assured from the high x-ray doses used. This article reports our collaboration's first attempt at SPI using the SACLA XFEL facility in June 2015. The report is limited to experience with the instrumentation and examples of data because we have not yet had time to invert them to images.
DC.rights	© 2015 IOP Publishing Ltd. This article is licensed under a Creative Commons Attribution 3.0 Unported License.
DC.format	79030
citation_title	Towards single particle imaging of human chromosomes at SACLA
citation_author	Robinson, Ian
	Schwenke, Joerg
	Yusuf, Mohammed
	Estandarte, Ana
	Zhang, Fucai
	Chen, Bo
	Clark, Jesse
	Song, Changyong
	Nam, Daewoong
	Joti, Yasumasa
	Tono, Kensuke
	Yabashi, Makina
	Ratnasari, Gina
	Kaneyoshi, Kohei
	Takata, Hideaki
	Fukui, Kiichi
citation_publisher	Institute of Physics Publishing
citation_language	英語
citation_date	2015-11-03
citation_journal_title	Journal of Physics B: Atomic, Molecular and Optical Physics
citation_volume	48
citation_issue	24
citation_firstpage	244007
citation_doi	https://doi.org/10.1088/0953-4075/48/24/244007
citation_public_url	https://hdl.handle.net/11094/79030

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