Stability enhancement of 129Xe hyperpolarizing system using alkali metal vapor in spin-exchange optical pumping cell to achieve high NMR sensitivity

Fujiwara, Hideaki; Imai, Hirohiko; Kimura, Atsuomi

doi:https://doi.org/10.2116/analsci.19P047

Stability enhancement of 129Xe hyperpolarizing system using alkali metal vapor in spin-exchange optical pumping cell to achieve high NMR sensitivity

Fujiwara, Hideaki; Imai, Hirohiko; Kimura, Atsuomi

Analytical Sciences, 2019, 35(8), 869-873

アクセス数:327件（2025-09-04 10:37 集計）

固定URL: https://hdl.handle.net/11094/88639

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タイトル	Stability enhancement of 129Xe hyperpolarizing system using alkali metal vapor in spin-exchange optical pumping cell to achieve high NMR sensitivity
著者	NRID 1000090107102 1000090107102 著者名 Fujiwara, Hideaki
	NRID 1000040506466 1000040506466 著者名 Imai, Hirohiko
	NRID 1000070303972 1000070303972 researchmap permalink osaka_kimura osaka_kimura Scopus Author ID 7402712083 7402712083 ORCID 0000-0001-5702-276X 0000-0001-5702-276X 著者名 Kimura, Atsuomi
キーワード等	129Xe
	Cell decay constant
	Hyperpolarized
	Nanofiber
	NMR
	Rb degradation
	SN improvement
抄録	Hyperpolarized (HP) 129Xe NMR and MRI have enabled 129Xe studies with extraordinarily enhanced sensitivity, stimulating new developments in magnetic resonance in chemistry, physics, biology and medicine. However, the standard method of HP 129Xe production inevitably demands Rb vapor for the excitation, which has made the method very sensitive to impurities such as water or oxygen. This is the case especially in the recirculating system. In the present study, stability of the hyperpolarizing system is discussed by proposing the "cell decay constant", which symbolizes the decay rate of the NMR signal obtained from the system. The cell decay constant is effectively decreased to 1/3 by introducing separated chambers and mechanical stirring of the alkali metals used in the system, making it effective for accumulating FIDs over 30 to 100 h. The newly developed hyperpolarizing system has been successfully applied for newly detecting a broad signal at 190 ppm with an industrial material Nanofiber.
出版者	Japan Society for Analytical Chemistry
出版者	日本分析化学会
収録物名	Analytical Sciences
巻(号)	35(8)
ページ	869-873
刊行年月	2019-08-10
言語	英語
ハンドルURL	https://hdl.handle.net/11094/88639
PISSN	09106340
eISSN	13482246
NCID	AA12022210
NCID	AA10500785
関連情報 (isIdenticalTo)	DOI (出版社版) https://doi.org/10.2116/analsci.19P047
関連情報 (isIdenticalTo)	PMID 30982799
アクセス権	open access
出版タイプ	Version of Record
カテゴリ	学術雑誌論文 Journal Article

資源タイプ	学術雑誌論文
ローカル資源タイプ	学術雑誌論文
DCMI資源タイプ	text
DCTERMS.bibliographicCitation	Analytical Sciences. 2019, 35(8), p. 869-873
DC.title	Stability enhancement of 129Xe hyperpolarizing system using alkali metal vapor in spin-exchange optical pumping cell to achieve high NMR sensitivity
DC.creator	Fujiwara, Hideaki
	Imai, Hirohiko
	Kimura, Atsuomi
DC.publisher	Japan Society for Analytical Chemistry
DC.publisher	日本分析化学会
DC.language' scheme='DCTERMS.RFC1766	英語
DC.type' scheme='DCTERMS.DCMIType	text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2019-08-10
DC.identifier	https://doi.org/10.2116/analsci.19P047
DC.subject	129Xe
	Cell decay constant
	Hyperpolarized
	Nanofiber
	NMR
	Rb degradation
	SN improvement
DCTERMS.abstract	Hyperpolarized (HP) 129Xe NMR and MRI have enabled 129Xe studies with extraordinarily enhanced sensitivity, stimulating new developments in magnetic resonance in chemistry, physics, biology and medicine. However, the standard method of HP 129Xe production inevitably demands Rb vapor for the excitation, which has made the method very sensitive to impurities such as water or oxygen. This is the case especially in the recirculating system. In the present study, stability of the hyperpolarizing system is discussed by proposing the "cell decay constant", which symbolizes the decay rate of the NMR signal obtained from the system. The cell decay constant is effectively decreased to 1/3 by introducing separated chambers and mechanical stirring of the alkali metals used in the system, making it effective for accumulating FIDs over 30 to 100 h. The newly developed hyperpolarizing system has been successfully applied for newly detecting a broad signal at 190 ppm with an industrial material Nanofiber.
DC.format	88639
citation_title	Stability enhancement of 129Xe hyperpolarizing system using alkali metal vapor in spin-exchange optical pumping cell to achieve high NMR sensitivity
citation_author	Fujiwara, Hideaki
	Imai, Hirohiko
	Kimura, Atsuomi
citation_publisher	Japan Society for Analytical Chemistry
citation_language	英語
citation_date	2019-08-10
citation_journal_title	Analytical Sciences
citation_volume	35
citation_issue	8
citation_firstpage	869
citation_lastpage	873
citation_doi	https://doi.org/10.2116/analsci.19P047
citation_pmid	30982799
citation_public_url	https://hdl.handle.net/11094/88639

Stability enhancement of 129Xe hyperpolarizing system using alkali metal vapor in spin-exchange optical pumping cell to achieve high NMR sensitivity

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