学術雑誌論文

学術雑誌論文

text

Organic Letters. 2021, 23(16), p. 6252-6256

Sulfur-Directed C7-Selective Alkenylation of Indoles under Rhodium Catalysis

American Chemical Society

英語

text

2021-08-20

https://doi.org/10.1021/acs.orglett.1c01990

Kona C.N., Nishii Y., Miura M.. Sulfur-Directed C7-Selective Alkenylation of Indoles under Rhodium Catalysis. Organic Letters. 23(16), 6252-6256, (2021), 20 August 2022; ©2021 American Chemical Society. https://doi.org/10.1021/acs.orglett.1c01990.

Regioselective direct functionalization of an indole benzenoid fragment has been a significant challenge be-cause of its inherently lower reactivity. In this report, we introduce a Rh-catalyzed C7-selective alkenylation of indole de-rivatives utilizing a new sulfur directing group N-SCy. A notable feature of this system is that the directing group is readily installed to the indoles and easily removed after the catalysis under mild conditions.

This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.1c01990.

92808

Sulfur-Directed C7-Selective Alkenylation of Indoles under Rhodium Catalysis

American Chemical Society

英語

2021-08-20

Organic Letters

23

16

6252

6256

https://doi.org/10.1021/acs.orglett.1c01990

https://hdl.handle.net/11094/92808