学術雑誌論文

学術雑誌論文

text

ACS Catalysis. 2019, 9(12), p. 11455-11460

Rhodium-Catalyzed Annulative Coupling Using Vinylene Carbonate as an Oxidizing Acetylene Surrogate

American Chemical Societyservice

英語

text

2019-12-06

https://doi.org/10.1021/acscatal.9b04254

Ghosh K., Nishii Y., Miura M.. Rhodium-Catalyzed Annulative Coupling Using Vinylene Carbonate as an Oxidizing Acetylene Surrogate. ACS Catalysis. 9(12), 11455-11460, (2019), 6 December 2019; ©2019 American Chemical Society. https://doi.org/10.1021/acscatal.9b04254.

Transition-metal-catalyzed C–H activation and subsequent oxidative cyclization with alkynes has been a pow-erful tool for the synthesis of polycyclic aromatic compounds. Despite the substantial progress in this field, it is still a significant challenge to establish synthetic methodologies for the construction of non-substituted vinylene-fused aromatics. We herein report a Rh(III)-catalyzed C–H/N–H annulation with vinylene carbonate as an acetylene surrogate. Vinylene carbonate also acts as an internal oxidant to regenerate the Rh(III) species in situ; thus no external oxidant is required to trigger the oxidative annulation. This protocol is applicable to the direct synthesis of various N-heteroaromatics.

This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Catalysis, © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acscatal.9b04254.

92818

Rhodium-Catalyzed Annulative Coupling Using Vinylene Carbonate as an Oxidizing Acetylene Surrogate

American Chemical Societyservice

英語

2019-12-06

ACS Catalysis

9

12

11455

11460

https://doi.org/10.1021/acscatal.9b04254

https://hdl.handle.net/11094/92818