In vivo tomographic visualization of intracochlear vibration using a supercontinuum multifrequency-swept optical coherence microscope

Choi, Samuel; Nin, Fumiaki; Ota, Takeru; Sato, Kouhei; Muramatsu, Shogo; Hibino, Hiroshi

doi:https://doi.org/10.1364/BOE.10.003317

In vivo tomographic visualization of intracochlear vibration using a supercontinuum multifrequency-swept optical coherence microscope

Choi, Samuel; Nin, Fumiaki; Ota, Takeru et al.

Biomedical Optics Express, 2019, 10(7), 3317-3342

アクセス数:786件（2025-08-01 16:17 集計）

固定URL: https://hdl.handle.net/11094/93417

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タイトル	In vivo tomographic visualization of intracochlear vibration using a supercontinuum multifrequency-swept optical coherence microscope
著者	NRID 1000060568418 1000060568418 著者名 Choi, Samuel
	NRID 1000080644905 1000080644905 著者名 Nin, Fumiaki
	NRID 1000030790571 1000030790571 ORCID 0000-0003-0011-8925 0000-0003-0011-8925 researchmap permalink otatakeru otatakeru Scopus Author ID 26642091900 26642091900 著者名 Ota, Takeru
	著者名 Sato, Kouhei
	NRID 1000030295472 1000030295472 著者名 Muramatsu, Shogo
	NRID 1000070314317 1000070314317 researchmap permalink hiroshi_hibino hiroshi_hibino Scopus Author ID 7007020846 7007020846 著者名 Hibino, Hiroshi
内容	Choi S., Nin F., Ota T., et al. In vivo tomographic visualization of intracochlear vibration using a supercontinuum multifrequency-swept optical coherence microscope. Biomedical Optics Express 10, 3317 (2019); https://doi.org/10.1364/BOE.10.003317.
抄録	This study combined a previously developed optical system with two additional key elements: a supercontinuum light source characterized by high output power and an analytical technique that effectively extracts interference signals required for improving the detection limit of vibration amplitude. Our system visualized 3D tomographic images and nanometer scale vibrations in the cochlear sensory epithelium of a live guinea pig. The transverse- and axial-depth resolution was 3.6 and 2.7 µm, respectively. After exposure to acoustic stimuli of 21-25 kHz at a sound pressure level of 70-85 dB, spatial amplitude and phase distributions were quantified on a targeted surface, whose area was 522 × 522 µm2.
出版者	OPTICA Publishing Group
収録物名	Biomedical Optics Express
巻(号)	10(7)
ページ	3317-3342
刊行年月	2019-07-01
言語	英語
ハンドルURL	https://hdl.handle.net/11094/93417
eISSN	21567085
関連情報 (isIdenticalTo)	DOI (出版社版) https://doi.org/10.1364/BOE.10.003317
アクセス権	open access
権利情報	© 2019 Optica Publishing Group. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.
出版タイプ	Version of Record
カテゴリ	学術雑誌論文 Journal Article

資源タイプ	学術雑誌論文
ローカル資源タイプ	学術雑誌論文
DCMI資源タイプ	text
DCTERMS.bibliographicCitation	Biomedical Optics Express. 2019, 10(7), p. 3317-3342
DC.title	In vivo tomographic visualization of intracochlear vibration using a supercontinuum multifrequency-swept optical coherence microscope
DC.creator	Choi, Samuel
	Nin, Fumiaki
	Ota, Takeru
	Sato, Kouhei
	Muramatsu, Shogo
	Hibino, Hiroshi
DC.publisher	OPTICA Publishing Group
DC.language' scheme='DCTERMS.RFC1766	英語
DC.type' scheme='DCTERMS.DCMIType	text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2019-07-01
DC.identifier	https://doi.org/10.1364/BOE.10.003317
DC.description	Choi S., Nin F., Ota T., et al. In vivo tomographic visualization of intracochlear vibration using a supercontinuum multifrequency-swept optical coherence microscope. Biomedical Optics Express 10, 3317 (2019); https://doi.org/10.1364/BOE.10.003317.
DCTERMS.abstract	This study combined a previously developed optical system with two additional key elements: a supercontinuum light source characterized by high output power and an analytical technique that effectively extracts interference signals required for improving the detection limit of vibration amplitude. Our system visualized 3D tomographic images and nanometer scale vibrations in the cochlear sensory epithelium of a live guinea pig. The transverse- and axial-depth resolution was 3.6 and 2.7 µm, respectively. After exposure to acoustic stimuli of 21-25 kHz at a sound pressure level of 70-85 dB, spatial amplitude and phase distributions were quantified on a targeted surface, whose area was 522 × 522 µm2.
DC.rights	© 2019 Optica Publishing Group. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.
DC.format	93417
citation_title	In vivo tomographic visualization of intracochlear vibration using a supercontinuum multifrequency-swept optical coherence microscope
citation_author	Choi, Samuel
	Nin, Fumiaki
	Ota, Takeru
	Sato, Kouhei
	Muramatsu, Shogo
	Hibino, Hiroshi
citation_publisher	OPTICA Publishing Group
citation_language	英語
citation_date	2019-07-01
citation_journal_title	Biomedical Optics Express
citation_volume	10
citation_issue	7
citation_firstpage	3317
citation_lastpage	3342
citation_doi	https://doi.org/10.1364/BOE.10.003317
citation_public_url	https://hdl.handle.net/11094/93417

In vivo tomographic visualization of intracochlear vibration using a supercontinuum multifrequency-swept optical coherence microscope

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