Masked diabetes insipidus in pituitary metastasis from breast cancer after thalamic biopsy: a case report

Hashimoto, Hiroaki; Maruo, Tomoyuki; Nakamura, Masami et al.

Journal of Medical Case Reports, 2022, 16, 12

アクセス数:962件（2025-09-04 13:23 集計）

固定URL: https://hdl.handle.net/11094/95629

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タイトル
Masked diabetes insipidus in pituitary metastasis from breast cancer after thalamic biopsy: a case report
著者
NRID
1000050770674 1000050770674
ORCID
0000-0003-4057-4466 0000-0003-4057-4466
researchmap permalink
yousyou0720 yousyou0720
Scopus Author ID
56922570200 56922570200
著者名
Hashimoto, Hiroaki
NRID
1000090533810 1000090533810
researchmap permalink
tomaruo0611 tomaruo0611
著者名
Maruo, Tomoyuki
著者名
Nakamura, Masami
NRID
1000020028583 1000020028583
著者名
Ushio, Yukitaka
NRID
1000030372626 1000030372626
researchmap permalink
hiratty hiratty
Scopus Author ID
7403352253 7403352253
著者名
Hirata, Masayuki
NRID
1000010332743 1000010332743
researchmap permalink
hkishima hkishima
Scopus Author ID
6603783358 6603783358
ORCID
0000-0002-9041-2337 0000-0002-9041-2337
著者名
Kishima, Haruhiko
キーワード等
Breast cancer
Case report
Masked diabetes insipidus
Panhypopituitarism
Pituitary metastasis
Stereotactic biopsy
内容
Hashimoto H., Maruo T., Nakamura M., et al. Masked diabetes insipidus in pituitary metastasis from breast cancer after thalamic biopsy: a case report. Journal of Medical Case Reports 16, 12 (2022); https://doi.org/10.1186/s13256-021-03229-y.
抄録
Background: Symptomatic pituitary metastasis is rare; furthermore, it can result in diabetes insipidus and panhypopituitarism. Since diabetes insipidus is masked by concurrent panhypopituitarism, it can impede the diagnosis of pituitary dysfunction. Case presentation: A 68-year-old Japanese female suffering from pituitary and thalamic metastases caused by untreated breast cancer, underwent a biopsy targeting the thalamus, not the pituitary. She lacked prebiopsy pituitary dysfunction symptoms; however, these symptoms unexpectedly occurred after biopsy. Diabetes insipidus was masked by corticosteroid insufficiency, and she showed normal urinary output and plasma sodium levels. Upon commencement of glucocorticoid replacement therapy, the symptoms of diabetes insipidus appeared. Conclusions: In this case, thalamic biopsy, as opposed to pituitary biopsy, was performed to preserve pituitary function. However, pituitary dysfunction could not be avoided. Caution is necessary for asymptomatic patients with pituitary metastases as invasive interventions, such as surgery, may induce pituitary dysfunction. Moreover, with respect to masked diabetes insipidus, there is a need to carefully consider pituitary dysfunction to avoid misdiagnosis and delayed treatment.
出版者
BioMed Central Ltd
収録物名
Journal of Medical Case Reports
巻(号)
16
ページ
12
刊行年月
2022-12-01
言語
英語
ハンドルURL
https://hdl.handle.net/11094/95629
eISSN
17521947
関連情報 (isIdenticalTo)
DOI (出版社版)
https://doi.org/10.1186/s13256-021-03229-y
アクセス権
open access
権利情報
This article is licensed under a Creative Commons Attribution 4.0 International License.
出版タイプ
Version of Record
カテゴリ
学術雑誌論文 Journal Article