学術雑誌論文

学術雑誌論文

text

Organic Letters. 2024, 26(20), p. 4268-4273

Nickel-Catalyzed Electrophilic Amination of the Biphenylene C-C σ-Bond

American Chemical Society

英語

text

2024-05-24

https://doi.org/10.1021/acs.orglett.4c01226

Inoue T., Nishino S., Yasui K., et al. Nickel-Catalyzed Electrophilic Amination of the Biphenylene C-C σ-Bond. Organic Letters 26, 4268 (2024); https://doi.org/10.1021/acs.orglett.4c01226.

A nickel-catalyzed three-component carboamination of the biphenylene C-C σ-bond has been developed. Arylboronates and hydroxylamine derivatives work as carbon nucleophiles and nitrogen electrophiles, respectively, and the corresponding difunctionalized ring-opening products are obtained in good yields. The arylboronate nucleophile can be replaced with B₂pin₂ (boron nucleophile) and H-Si(OMe)₃ (hydride nucleophile), thus allowing for the aminoboration and hydroamination of the biphenylene C-C σ-bond under similar nickel catalysis.

This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.4c01226.

95798

Nickel-Catalyzed Electrophilic Amination of the Biphenylene C-C σ-Bond

American Chemical Society

英語

2024-05-24

Organic Letters

26

20

4268

4273

https://doi.org/10.1021/acs.orglett.4c01226

https://hdl.handle.net/11094/95798