学術雑誌論文

学術雑誌論文

Nature Communications. 2024, 15(1), p. 4078

Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans

Nature Research

英語

2024-05-22

https://doi.org/10.1038/s41467-024-48367-1

Iwata T., Yanagisawa T., Ikegaya Y., et al. Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans. Nature Communications 15, 4078 (2024); https://doi.org/https://doi.org/10.1038/s41467-024-48367-1.

Core features of human cognition highlight the importance of the capacity to focus on information distinct from events in the here and now, such as mind wandering. However, the brain mechanisms that underpin these self-generated states remain unclear. An emerging hypothesis is that self-generated states depend on the process of memory replay, which is linked to sharp-wave ripples (SWRs), which are transient high-frequency oscillations originating in the hippocampus. Local field potentials were recorded from the hippocampus of 10 patients with epilepsy for up to 15 days, and experience sampling was used to describe their association with ongoing thought patterns. The SWR rates were higher during extended periods of time when participants’ ongoing thoughts were more vivid, less desirable, had more imaginable properties, and exhibited fewer correlations with an external task. These data suggest a role for SWR in the patterns of ongoing thoughts that humans experience in daily life.

This article is licensed under a Creative Commons Attribution 4.0 International License.

97800

Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans

Nature Research

英語

2024-05-22

Nature Communications

15

1

4078

https://doi.org/10.1038/s41467-024-48367-1

https://hdl.handle.net/11094/97800