Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study

Ohata, Yuka; Kabayama, Mai; Godai, Kayo; Kido, Michiko; Li, Yaya; Akagi, Yuya; Murakami, Naoko; Yoshida, Hiroko; Hosokawa, Mariko; Tachibana, Yuka; Fukata, Yuka; Anzai, Chihiro; Hatta, Kaoru; Maeyama, Yurie; Wada, Arisa; Hashimoto, Sumiyo; Hatanaka, Hiromi; Higashi, Makiko; Kikuchi, Takeshi; Terauchi, Keiji; Matsuno, Fumie; Nagayoshi, Sho; Asayama, Kei; Ohkubo, Takayoshi; Rakugi, Hiromi; Tabara, Yasuharu; Kamide, Kei

doi:https://doi.org/10.1038/s41440-025-02145-8

Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study

Ohata, Yuka; Kabayama, Mai; Godai, Kayo et al.

Hypertension Research, 2025

Number of Access:2,544（2025-10-24 12:42 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/100451

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Title	Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study
Creator	CreatorName Ohata, Yuka
	NRID 1000050635498 1000050635498 ORCID 0000-0003-1394-1152 0000-0003-1394-1152 researchmap permalink kabayama kabayama Scopus Author ID 57031780400 57031780400 CreatorName Kabayama, Mai
	NRID 1000030708681 1000030708681 researchmap permalink vince vince Scopus Author ID 56781372400 56781372400 CreatorName Godai, Kayo
	NRID 1000000706913 1000000706913 researchmap permalink 051010 051010 Scopus Author ID 56086201900 56086201900 CreatorName Kido, Michiko
	NRID 1000060982030 1000060982030 researchmap permalink lia lia CreatorName Li, Yaya
	researchmap permalink yuya-akagi yuya-akagi CreatorName Akagi, Yuya
	CreatorName Murakami, Naoko
	CreatorName Yoshida, Hiroko
	CreatorName Hosokawa, Mariko
	CreatorName Tachibana, Yuka
	CreatorName Fukata, Yuka
	CreatorName Anzai, Chihiro
	CreatorName Hatta, Kaoru
	CreatorName Maeyama, Yurie
	CreatorName Wada, Arisa
	CreatorName Hashimoto, Sumiyo
	CreatorName Hatanaka, Hiromi
	CreatorName Higashi, Makiko
	CreatorName Kikuchi, Takeshi
	CreatorName Terauchi, Keiji
	CreatorName Matsuno, Fumie
	CreatorName Nagayoshi, Sho
	NRID 1000080431518 1000080431518 CreatorName Asayama, Kei
	NRID 1000060344652 1000060344652 CreatorName Ohkubo, Takayoshi
	NRID 1000020252679 1000020252679 ORCID 0000-0001-6508-4338 0000-0001-6508-4338 researchmap permalink read0042763 read0042763 Scopus Author ID 57202699453 57202699453 CreatorName Rakugi, Hiromi
	NRID 1000000268749 1000000268749 researchmap permalink yasuharu.tabara yasuharu.tabara CreatorName Tabara, Yasuharu
	NRID 1000080393239 1000080393239 researchmap permalink kamide kamide Scopus Author ID 7102978326 7102978326 ORCID 0000-0003-1720-2218 0000-0003-1720-2218 CreatorName Kamide, Kei
Subject	Community-dwelling older adults
	Frailty
	Home blood pressure
	Office blood pressure
	Self-measured
Description	The version of record of this article, first published in Hypertension Research, is available online at Publisher’s website: https://doi.org/10.1038/s41440-025-02145-8.
Abstract	The relationship between frailty and blood pressure (BP) is inconsistent, and limited research has compared BP by frailty status using long-term home BP measurements. We aimed to identify office and home BP and determine differences according to frailty status, stratified by taking antihypertensives in community-dwelling older adults. This cross-sectional study was part of the ongoing non-randomized intervention NOSE study. Participants were aged ≥ 64 years. Frailty was categorized robust, pre-frailty, or frailty using the revised Japanese version of the Cardiovascular Health Study criteria. Office BP was measured in survey settings, and each participant was instructed to take home BP. We used the average home BP for 4 weeks post-survey. An analysis of covariance analyzed the relationship between frailty and office and home BP, and their differences stratified by antihypertensive use. We included 418 older participants (mean age: 72.8 years); 39.5% were male, 40.4% were taking antihypertensives, and 6.7% had frailty. Individuals with frailty taking antihypertensives had higher home morning systolic BP (SBP) than those with robust (134.2 vs. 145.7 mmHg, P = 0.018) and pre-frailty (135.6 vs. 145.7 mmHg, P = 0.024). The difference between office and morning home SBP in treated participants was 7.1 mmHg (robust), 4.7 mmHg (pre-frailty), and −5.1 mmHg (frailty), showing significant differences (robust vs. frailty: P = 0.005, pre-frailty vs. frailty: P = 0.016). Home morning SBP was higher in individuals with frailty taking antihypertensives compared to those without frailty, and it may be higher than office BP. Individuals with frailty should measure home BP for good BP control.
Publisher	Springer Nature
Source Title	Hypertension Research
Date of Issued	2025-02-14
Language	English
Handle URL	https://hdl.handle.net/11094/100451
PISSN	09169636
eISSN	13484214
Relation.isIdenticalTo	DOI (Publisher Version) https://doi.org/10.1038/s41440-025-02145-8
Access Rights	open access
CopyRight	This article is licensed under a Creative Commons Attribution 4.0 International License.
oaire:version	Version of Record
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCTERMS.bibliographicCitation	Hypertension Research. 2025
DC.title	Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study
DC.creator	Ohata, Yuka
	Kabayama, Mai
	Godai, Kayo
	Kido, Michiko
	Li, Yaya
	Akagi, Yuya
	Murakami, Naoko
	Yoshida, Hiroko
	Hosokawa, Mariko
	Tachibana, Yuka
	Fukata, Yuka
	Anzai, Chihiro
	Hatta, Kaoru
	Maeyama, Yurie
	Wada, Arisa
	Hashimoto, Sumiyo
	Hatanaka, Hiromi
	Higashi, Makiko
	Kikuchi, Takeshi
	Terauchi, Keiji
	Matsuno, Fumie
	Nagayoshi, Sho
	Asayama, Kei
	Ohkubo, Takayoshi
	Rakugi, Hiromi
	Tabara, Yasuharu
	Kamide, Kei
DC.publisher	Springer Nature
DC.language' scheme='DCTERMS.RFC1766	English
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2025-02-14
DC.identifier	https://doi.org/10.1038/s41440-025-02145-8
DC.subject	Community-dwelling older adults
	Frailty
	Home blood pressure
	Office blood pressure
	Self-measured
DC.description	The version of record of this article, first published in Hypertension Research, is available online at Publisher’s website: https://doi.org/10.1038/s41440-025-02145-8.
DCTERMS.abstract	The relationship between frailty and blood pressure (BP) is inconsistent, and limited research has compared BP by frailty status using long-term home BP measurements. We aimed to identify office and home BP and determine differences according to frailty status, stratified by taking antihypertensives in community-dwelling older adults. This cross-sectional study was part of the ongoing non-randomized intervention NOSE study. Participants were aged ≥ 64 years. Frailty was categorized robust, pre-frailty, or frailty using the revised Japanese version of the Cardiovascular Health Study criteria. Office BP was measured in survey settings, and each participant was instructed to take home BP. We used the average home BP for 4 weeks post-survey. An analysis of covariance analyzed the relationship between frailty and office and home BP, and their differences stratified by antihypertensive use. We included 418 older participants (mean age: 72.8 years); 39.5% were male, 40.4% were taking antihypertensives, and 6.7% had frailty. Individuals with frailty taking antihypertensives had higher home morning systolic BP (SBP) than those with robust (134.2 vs. 145.7 mmHg, P = 0.018) and pre-frailty (135.6 vs. 145.7 mmHg, P = 0.024). The difference between office and morning home SBP in treated participants was 7.1 mmHg (robust), 4.7 mmHg (pre-frailty), and −5.1 mmHg (frailty), showing significant differences (robust vs. frailty: P = 0.005, pre-frailty vs. frailty: P = 0.016). Home morning SBP was higher in individuals with frailty taking antihypertensives compared to those without frailty, and it may be higher than office BP. Individuals with frailty should measure home BP for good BP control.
DC.rights	This article is licensed under a Creative Commons Attribution 4.0 International License.
DC.format	100451
citation_title	Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study
citation_author	Ohata, Yuka
	Kabayama, Mai
	Godai, Kayo
	Kido, Michiko
	Li, Yaya
	Akagi, Yuya
	Murakami, Naoko
	Yoshida, Hiroko
	Hosokawa, Mariko
	Tachibana, Yuka
	Fukata, Yuka
	Anzai, Chihiro
	Hatta, Kaoru
	Maeyama, Yurie
	Wada, Arisa
	Hashimoto, Sumiyo
	Hatanaka, Hiromi
	Higashi, Makiko
	Kikuchi, Takeshi
	Terauchi, Keiji
	Matsuno, Fumie
	Nagayoshi, Sho
	Asayama, Kei
	Ohkubo, Takayoshi
	Rakugi, Hiromi
	Tabara, Yasuharu
	Kamide, Kei
citation_publisher	Springer Nature
citation_language	English
citation_date	2025-02-14
citation_journal_title	Hypertension Research
citation_doi	https://doi.org/10.1038/s41440-025-02145-8
citation_public_url	https://hdl.handle.net/11094/100451

Office and home blood pressure and their difference according to frailty status among community-dwelling older adults: the NOSE study

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