Effects of multiple tongue conditions on the diversity and composition of the oral microbiota

Hamada, Masakazu; Matsuoka, Yuriko; Ogaya, Yuko et al.

Journal of Oral Microbiology, 2026, 18(1), 2684141

Number of Access:162（2026-09-08 10:14 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/106069

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Title
Effects of multiple tongue conditions on the diversity and composition of the oral microbiota
Creator
NRID
1000080506361 1000080506361
researchmap permalink
6361 6361
Scopus Author ID
36616148000 36616148000
CreatorName
Hamada, Masakazu
NRID
1000070865790 1000070865790
CreatorName
Matsuoka, Yuriko
NRID
1000040803078 1000040803078
researchmap permalink
y_ogaya y_ogaya
Scopus Author ID
56460237100 56460237100
CreatorName
Ogaya, Yuko
NRID
1000010908643 1000010908643
ORCID
0009-0007-6613-0093 0009-0007-6613-0093
researchmap permalink
kadota-tamami kadota-tamami
Scopus Author ID
57204146709 57204146709
CreatorName
Kadota, Tamami
CreatorName
Ikeda, Shunya
NRID
1000090909681 1000090909681
CreatorName
Akitomo, Tatsuya
NRID
1000090437385 1000090437385
CreatorName
Nomura, Ryota
NRID
1000000379083 1000000379083
ORCID
0000-0002-2209-2685 0000-0002-2209-2685
researchmap permalink
read0202427 read0202427
Scopus Author ID
7402011667 7402011667
CreatorName
Nakano, Kazuhiko
Subject
fissured tongue
oral cavity
oral microbiome
saliva
tongue coating
Tongue condition
Description
Hamada M., Matsuoka Y., Ogaya Y., et al. Effects of multiple tongue conditions on the diversity and composition of the oral microbiota. Journal of Oral Microbiology 18, 2684141 (2026); https://doi.org/10.1080/20002297.2026.2684141.
Abstract
Objective: The present study examined the effects of multiple tongue conditions on the diversity and composition of the oral microbiota to obtain a more detailed understanding of their potential role in health and disease. Method: Ninety-three subjects were classified according to tongue conditions, such as a yellow tongue coating, the presence or absence of swelling of the sublingual vein, a red tongue or red tongue tip, a fissured tongue, enlarged tongue, geographic tongue, and tooth marks. The oral microbiota was examined using α- and β-diversity metrics and taxonomic composition analyses. Results: α-Diversity was significantly lower in subjects with a fissured tongue than in those without. A β-diversity analysis revealed distinct microbial community structures between these subjects. Taxonomic profiling showed a higher abundance of Firmicutes and sulfur-metabolizing bacteria in subjects with a fissured tongue. However, these differences were not retained after age adjustment. Age-restricted sensitivity analyses identified age-independent microbial signatures associated with a fissured tongue, including a reduced abundance of Veillonella and Granulicatella in saliva samples. Conclusion: Morphological abnormalities of the tongue are associated with distinct oral microbiome profiles. These features may reflect oral microbial dysbiosis and could be relevant for future studies exploring non-invasive markers of oral health.
Publisher
Taylor and Francis Ltd.
Source Title
Journal of Oral Microbiology
Volume (Issue)
18(1)
Page
2684141
Date of Issued
2026-06-07
Language
English
Handle URL
https://hdl.handle.net/11094/106069
eISSN
20002297
Relation.isIdenticalTo
DOI (Publisher Version)
https://doi.org/10.1080/20002297.2026.2684141
Access Rights
open access
CopyRight
This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
oaire:version
Version of Record
Category
学術雑誌論文 Journal Article