Effect of daily swallowing frequency on swallowing-related muscle mass in individuals with severe motor and intellectual disability

Uota, Chisato; Nohara, Kanji; Tanaka, Nobukazu et al.

Brain and Development, 2026, 48(4), 104553

Number of Access:112（2026-09-28 07:37 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/106282

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Title
Effect of daily swallowing frequency on swallowing-related muscle mass in individuals with severe motor and intellectual disability
Creator
CreatorName
Uota, Chisato
NRID
1000020346167 1000020346167
ORCID
0000-0001-8254-4615 0000-0001-8254-4615
researchmap permalink
read0093430 read0093430
Scopus Author ID
7004385707 7004385707
CreatorName
Nohara, Kanji
NRID
1000020570295 1000020570295
ORCID
0000-0002-5877-0214 0000-0002-5877-0214
researchmap permalink
hal-1008 hal-1008
Scopus Author ID
55702171000 55702171000
CreatorName
Tanaka, Nobukazu
NRID
1000090635377 1000090635377
ORCID
0000-0003-3670-3085 0000-0003-3670-3085
researchmap permalink
nanohana-3 nanohana-3
CreatorName
Fujii, Nami
researchmap permalink
Aya-Obana Aya-Obana
Scopus Author ID
57798291700 57798291700
ORCID
0009-0001-3107-5588 0009-0001-3107-5588
CreatorName
Obana, Aya
CreatorName
Tanaka, Katsuji
NRID
1000090379082 1000090379082
ORCID
0000-0003-4348-4896 0000-0003-4348-4896
researchmap permalink
read0210126 read0210126
Scopus Author ID
55177911100 55177911100
CreatorName
Sakai, Takayoshi
Subject
Deglutition disorders
Dysphagia
Geniohyoid muscle
Intellectual disability
Muscular atrophy
Swallowing
Description
Uota C., Nohara K., Tanaka N., et al. Effect of daily swallowing frequency on swallowing-related muscle mass in individuals with severe motor and intellectual disability. Brain and Development 48(4), 104553 (2026); https://doi.org/10.1016/j.braindev.2026.104553.
Abstract
Background: Among the causes of dysphagia in individuals with severe motor and intellectual disability (SMID), addressing disuse atrophy of swallowing-related muscles are expected to improve patient outcomes. Disuse atrophy is associated with a reduced frequency of muscle activity, and swallowing frequency may be associated with the atrophy of swallowing-related muscles. Objective: We aimed to investigate the relationship between swallowing frequency and swallowing-related muscle mass in individuals with SMID. Methods: This cross-sectional study included 62 individuals with SMID (31 men and 31 women; mean age: 46.9 [standard deviation, 13.2] years) admitted to our center. Swallowing frequency was measured using a laryngeal microphone, and swallowing-related muscle mass was estimated by measuring the cross-sectional area of the geniohyoid muscle (GHM) using an ultrasonic diagnostic device. Results: Increased swallowing frequency and body weight corresponded to a larger cross-sectional area of the GHM. Moreover, women had a smaller GHM cross-sectional area than men. Multiple regression analysis showed that the swallowing frequency, body weight, and sex were significantly and independently associated with the GHM cross-sectional area (p < 0.01). Conclusions: Swallowing frequency and body weight significantly affect swallowing-related muscle mass in individuals with SMID.
Publisher
Elsevier B.V.
Source Title
Brain and Development
Volume (Issue)
48(4)
Page
104553
Date of Issued
2026-05-29
Language
English
Handle URL
https://hdl.handle.net/11094/106282
PISSN
03877604
eISSN
18727131
Relation.isIdenticalTo
DOI (Publisher Version)
https://doi.org/10.1016/j.braindev.2026.104553
Access Rights
open access
CopyRight
This article is licensed under a Creative Commons Attribution 4.0 International License.
oaire:version
Version of Record
Category
学術雑誌論文 Journal Article