Rationale, design, and profile of Comprehensive Registry of In-Hospital Intensive Care for OHCA Survival (CRITICAL) study in Osaka, Japan

Yamada, Tomoki; Kitamura, Tetsuhisa; Hayakawa, Koichi; Yoshiya, Kazuhisa; Irisawa, Taro; Abe, Yoshio; Ishiro, Megumi; Uejima, Toshifumi; Ohishi, Yasuo; Kaneda, Kazuhisa; Kiguchi, Takeyuki; Kishi, Masashi; Kishimoto, Masafumi; Nakao, Shota; Nishimura, Tetsuro; Hayashi, Yasuyuki; Morooka, Takaya; Izawa, Junichi; Shimamoto, Tomonari; Hatakeyama, Toshihiro; Matsuyama, Tasuku; Kawamura, Takashi; Shimazu, Takeshi; Iwami, Taku

doi:https://doi.org/10.1186/s40560-016-0128-5

Rationale, design, and profile of Comprehensive Registry of In-Hospital Intensive Care for OHCA Survival (CRITICAL) study in Osaka, Japan

Yamada, Tomoki; Kitamura, Tetsuhisa; Hayakawa, Koichi et al.

Journal of Intensive Care, 2016, 4, 10

Number of Access:2,595（2025-07-19 13:49 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/78408

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Title	Rationale, design, and profile of Comprehensive Registry of In-Hospital Intensive Care for OHCA Survival (CRITICAL) study in Osaka, Japan
Creator	NRID 1000040623434 1000040623434 CreatorName Yamada, Tomoki
	NRID 1000030639810 1000030639810 ORCID 0000-0003-0107-0580 0000-0003-0107-0580 researchmap permalink Kitamura_T Kitamura_T Scopus Author ID 22234282700 22234282700 CreatorName Kitamura, Tetsuhisa
	NRID 1000060403086 1000060403086 CreatorName Hayakawa, Koichi
	NRID 1000040379201 1000040379201 CreatorName Yoshiya, Kazuhisa
	NRID 1000050379202 1000050379202 researchmap permalink taroiri taroiri Scopus Author ID 7006596493 7006596493 CreatorName Irisawa, Taro
	CreatorName Abe, Yoshio
	CreatorName Ishiro, Megumi
	CreatorName Uejima, Toshifumi
	CreatorName Ohishi, Yasuo
	CreatorName Kaneda, Kazuhisa
	NRID 1000030724380 1000030724380 CreatorName Kiguchi, Takeyuki
	CreatorName Kishi, Masashi
	CreatorName Kishimoto, Masafumi
	CreatorName Nakao, Shota
	CreatorName Nishimura, Tetsuro
	CreatorName Hayashi, Yasuyuki
	CreatorName Morooka, Takaya
	CreatorName Izawa, Junichi
	NRID 1000010828411 1000010828411 CreatorName Shimamoto, Tomonari
	CreatorName Hatakeyama, Toshihiro
	NRID 1000050829025 1000050829025 CreatorName Matsuyama, Tasuku
	NRID 1000010252230 1000010252230 CreatorName Kawamura, Takashi
	NRID 1000050196474 1000050196474 CreatorName Shimazu, Takeshi
	NRID 1000060437291 1000060437291 CreatorName Iwami, Taku
Subject	Cohort
	CRITICAL
	In-hospital intensive care
	Out-of-hospital cardiac arrest
	Outcome
Description	Yamada, T., Kitamura, T., Hayakawa, K. et al. Rationale, design, and profile of Comprehensive Registry of In-Hospital Intensive Care for OHCA Survival (CRITICAL) study in Osaka, Japan. j intensive care 4, 10 (2016). https://doi.org/10.1186/s40560-016-0128-5
Abstract	Background: We established a multi-center, prospective cohort that could provide appropriate therapeutic strategies such as criteria for the introduction and the effectiveness of in-hospital advanced treatments, including percutaneous coronary intervention (PCI), target temperature management, and extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) patients. Methods: In Osaka Prefecture, Japan, we registered all consecutive patients who were suffering from an OHCA for whom resuscitation was attempted and who were then transported to institutions participating in this registry since July 1, 2012. A total of 11 critical care medical centers and one hospital with an emergency care department participated in this registry. The primary outcome was neurological status after OHCA, defined as cerebral performance category (CPC) scale. Results: A total of 688 OHCA patients were documented between July 2012 and December 2012. Of them, 657 were eligible for our analysis. Patients' average age was 66.2 years old, and male patients accounted for 66.2 %. The proportion of OHCAs having a cardiac origin was 50.4 %. The proportion as first documented rhythm of ventricular fibrillation/pulseless ventricular tachycardia was 11.6 %, pulseless electrical activity 23.4 %, and asystole 54.5 %. After hospital arrival, 10.5 % received defibrillation, 90.8 % tracheal intubation, 3.0 % ECPR, 3.5 % PCI, and 83.1 % adrenaline administration. The proportions of 90-day survival and CPC 1/2 at 90 days after OHCAs were 5.9 and 3.0 %, respectively. Conclusions: The Comprehensive Registry of In-hospital Intensive Care for OHCA Survival (CRITICAL) study will enroll over 2000 OHCA patients every year. It is still ongoing without a set termination date in order to provide valuable information regarding appropriate therapeutic strategies for OHCA patients (UMIN000007528).
Publisher	BioMed Central Ltd.
Source Title	Journal of Intensive Care
Volume (Issue)	4
Page	10
Date of Issued	2016-01-26
Language	English
Handle URL	https://hdl.handle.net/11094/78408
eISSN	20520492
Relation.isIdenticalTo	DOI (Publisher Version) https://doi.org/10.1186/s40560-016-0128-5
Access Rights	open access
CopyRight	© 2016 Yamada et al. This article is licensed under a Creative Commons Attribution 4.0 International License.
oaire:version	Version of Record
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCMI Type	Text
DCTERMS.bibliographicCitation	Journal of Intensive Care. 2016, 4, p. 10
DC.title	Rationale, design, and profile of Comprehensive Registry of In-Hospital Intensive Care for OHCA Survival (CRITICAL) study in Osaka, Japan
DC.creator	Yamada, Tomoki
	Kitamura, Tetsuhisa
	Hayakawa, Koichi
	Yoshiya, Kazuhisa
	Irisawa, Taro
	Abe, Yoshio
	Ishiro, Megumi
	Uejima, Toshifumi
	Ohishi, Yasuo
	Kaneda, Kazuhisa
	Kiguchi, Takeyuki
	Kishi, Masashi
	Kishimoto, Masafumi
	Nakao, Shota
	Nishimura, Tetsuro
	Hayashi, Yasuyuki
	Morooka, Takaya
	Izawa, Junichi
	Shimamoto, Tomonari
	Hatakeyama, Toshihiro
	Matsuyama, Tasuku
	Kawamura, Takashi
	Shimazu, Takeshi
	Iwami, Taku
DC.publisher	BioMed Central Ltd.
DC.language' scheme='DCTERMS.RFC1766	English
DC.type' scheme='DCTERMS.DCMIType	Text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2016-01-26
DC.identifier	https://doi.org/10.1186/s40560-016-0128-5
DC.subject	Cohort
	CRITICAL
	In-hospital intensive care
	Out-of-hospital cardiac arrest
	Outcome
DC.description	Yamada, T., Kitamura, T., Hayakawa, K. et al. Rationale, design, and profile of Comprehensive Registry of In-Hospital Intensive Care for OHCA Survival (CRITICAL) study in Osaka, Japan. j intensive care 4, 10 (2016). https://doi.org/10.1186/s40560-016-0128-5
DCTERMS.abstract	Background: We established a multi-center, prospective cohort that could provide appropriate therapeutic strategies such as criteria for the introduction and the effectiveness of in-hospital advanced treatments, including percutaneous coronary intervention (PCI), target temperature management, and extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) patients. Methods: In Osaka Prefecture, Japan, we registered all consecutive patients who were suffering from an OHCA for whom resuscitation was attempted and who were then transported to institutions participating in this registry since July 1, 2012. A total of 11 critical care medical centers and one hospital with an emergency care department participated in this registry. The primary outcome was neurological status after OHCA, defined as cerebral performance category (CPC) scale. Results: A total of 688 OHCA patients were documented between July 2012 and December 2012. Of them, 657 were eligible for our analysis. Patients' average age was 66.2 years old, and male patients accounted for 66.2 %. The proportion of OHCAs having a cardiac origin was 50.4 %. The proportion as first documented rhythm of ventricular fibrillation/pulseless ventricular tachycardia was 11.6 %, pulseless electrical activity 23.4 %, and asystole 54.5 %. After hospital arrival, 10.5 % received defibrillation, 90.8 % tracheal intubation, 3.0 % ECPR, 3.5 % PCI, and 83.1 % adrenaline administration. The proportions of 90-day survival and CPC 1/2 at 90 days after OHCAs were 5.9 and 3.0 %, respectively. Conclusions: The Comprehensive Registry of In-hospital Intensive Care for OHCA Survival (CRITICAL) study will enroll over 2000 OHCA patients every year. It is still ongoing without a set termination date in order to provide valuable information regarding appropriate therapeutic strategies for OHCA patients (UMIN000007528).
DC.rights	© 2016 Yamada et al. This article is licensed under a Creative Commons Attribution 4.0 International License.
DC.format	78408
citation_title	Rationale, design, and profile of Comprehensive Registry of In-Hospital Intensive Care for OHCA Survival (CRITICAL) study in Osaka, Japan
citation_author	Yamada, Tomoki
	Kitamura, Tetsuhisa
	Hayakawa, Koichi
	Yoshiya, Kazuhisa
	Irisawa, Taro
	Abe, Yoshio
	Ishiro, Megumi
	Uejima, Toshifumi
	Ohishi, Yasuo
	Kaneda, Kazuhisa
	Kiguchi, Takeyuki
	Kishi, Masashi
	Kishimoto, Masafumi
	Nakao, Shota
	Nishimura, Tetsuro
	Hayashi, Yasuyuki
	Morooka, Takaya
	Izawa, Junichi
	Shimamoto, Tomonari
	Hatakeyama, Toshihiro
	Matsuyama, Tasuku
	Kawamura, Takashi
	Shimazu, Takeshi
	Iwami, Taku
citation_publisher	BioMed Central Ltd.
citation_language	English
citation_date	2016-01-26
citation_journal_title	Journal of Intensive Care
citation_volume	4
citation_firstpage	10
citation_doi	https://doi.org/10.1186/s40560-016-0128-5
citation_public_url	https://hdl.handle.net/11094/78408

Rationale, design, and profile of Comprehensive Registry of In-Hospital Intensive Care for OHCA Survival (CRITICAL) study in Osaka, Japan

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