Osborn Wave Is Related to Ventricular Fibrillation and Tachycardia in Hypothermic Patients

Okada, Nobunaga; Matsuyama, Tasuku; Morita, Sachiko; Ehara, Naoki; Miyamae, Nobuhiro; Okada, Yohei; Jo, Takaaki; Sumida, Yasuyuki; Watanabe, Makoto; Nozawa, Masahiro; Tsuruoka, Ayumu; Fujimoto, Yoshihiro; Okumura, Yoshiki; Hamanaka, Kunio; Kitamura, Tetsuhisa; Nishiyama, Kei; Ohta, Bon

doi:https://doi.org/10.1253/circj.CJ-19-0856

Osborn Wave Is Related to Ventricular Fibrillation and Tachycardia in Hypothermic Patients

Okada, Nobunaga; Matsuyama, Tasuku; Morita, Sachiko et al.

Circulation journal, 2020, 84(3), 445-455

Number of Access:1,582（2025-10-21 11:11 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/78716

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Title	Osborn Wave Is Related to Ventricular Fibrillation and Tachycardia in Hypothermic Patients
Creator	CreatorName Okada, Nobunaga
	NRID 1000050829025 1000050829025 CreatorName Matsuyama, Tasuku
	CreatorName Morita, Sachiko
	CreatorName Ehara, Naoki
	CreatorName Miyamae, Nobuhiro
	CreatorName Okada, Yohei
	CreatorName Jo, Takaaki
	CreatorName Sumida, Yasuyuki
	CreatorName Watanabe, Makoto
	CreatorName Nozawa, Masahiro
	CreatorName Tsuruoka, Ayumu
	CreatorName Fujimoto, Yoshihiro
	CreatorName Okumura, Yoshiki
	CreatorName Hamanaka, Kunio
	NRID 1000030639810 1000030639810 ORCID 0000-0003-0107-0580 0000-0003-0107-0580 researchmap permalink Kitamura_T Kitamura_T Scopus Author ID 22234282700 22234282700 CreatorName Kitamura, Tetsuhisa
	NRID 1000090447970 1000090447970 CreatorName Nishiyama, Kei
	NRID 1000010596240 1000010596240 CreatorName Ohta, Bon
Subject	Hypothermia
	J wave
	Osborn wave
	Sudden cardiac death
	Ventricular arrhythmia
Description	Nobunaga Okada, Tasuku Matsuyama, Sachiko Morita, Naoki Ehara, Nobuhiro Miyamae, Yohei Okada, Takaaki Jo, Yasuyuki Sumida, Makoto Watanabe, Masahiro Nozawa, Ayumu Tsuruoka, Yoshihiro Fujimoto, Yoshiki Okumura, Kunio Hamanaka, Tetsuhisa Kitamura, Kei Nishiyama, Bon Ohta, Osborn Wave Is Related to Ventricular Fibrillation and Tachycardia in Hypothermic Patients, Circulation Journal, 2020, Volume 84, Issue 3, Pages 445-455, Released February 25, 2020, [Advance publication] Released January 30, 2020, Online ISSN 1347-4820, Print ISSN 1346-9843, https://doi.org/10.1253/circj.CJ-19-0856, https://www.jstage.jst.go.jp/article/circj/84/3/84_CJ-19-0856/_article/-char/en
Abstract	BACKGROUND: The Osborn wave (OW) is often observed in hypothermic patients; however, whether OW in hypothermic patients is related to the development of fatal ventricular arrhythmia, including ventricular fibrillation (VF) and pulseless ventricular tachycardia (VT), remains undetermined. This study aimed to estimate the association between OW and the incidence of fatal ventricular arrhythmias.Methods and Results: This retrospective study used the Japanese Accidental Hypothermia Network registry database and included 572 hypothermic patients. Patients were divided into the OW group (those with OW) and non-OW group (those without OW). The relationship between the development of fatal arrhythmias and presence of OW was assessed using the chi-squared test. All patients who developed VF/VT (n=10) had OW on electrocardiogram upon hospital arrival. The presence of OW had a sensitivity of 100%, specificity of 47.8%, positive predictive value of 4.0%, and negative predictive value of 100% for VF/VT development. The in-hospital mortality rate was 22.3% in the OW group and 21.2% in the non-OW group (P=0.781). CONCLUSIONS: OW was observed in all hypothermic patients with VF/VT. The occurrence of ventricular arrhythmias is highly unlikely in the absence of OW on the electrocardiogram. Although the presence of OW might be used to predict these fatal arrhythmias in hypothermic patients, there was no association between the presence of OW and in-hospital mortality.
Publisher	Japanese Circulation Society
Source Title	Circulation journal
Volume (Issue)	84(3)
Page	445-455
Date of Issued	2020-02-25
Language	English
Handle URL	https://hdl.handle.net/11094/78716
PISSN	13469843
eISSN	13474820
NCID	AA11591968
Relation.isIdenticalTo	DOI (Publisher Version) https://doi.org/10.1253/circj.CJ-19-0856
Relation.isIdenticalTo	PMID 31996488
Access Rights	open access
CopyRight	© 2020 The Japanese Circulation Society. This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
oaire:version	Version of Record
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCTERMS.bibliographicCitation	Circulation journal. 2020, 84(3), p. 445-455
DC.title	Osborn Wave Is Related to Ventricular Fibrillation and Tachycardia in Hypothermic Patients
DC.creator	Okada, Nobunaga
	Matsuyama, Tasuku
	Morita, Sachiko
	Ehara, Naoki
	Miyamae, Nobuhiro
	Okada, Yohei
	Jo, Takaaki
	Sumida, Yasuyuki
	Watanabe, Makoto
	Nozawa, Masahiro
	Tsuruoka, Ayumu
	Fujimoto, Yoshihiro
	Okumura, Yoshiki
	Hamanaka, Kunio
	Kitamura, Tetsuhisa
	Nishiyama, Kei
	Ohta, Bon
DC.publisher	Japanese Circulation Society
DC.language' scheme='DCTERMS.RFC1766	English
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2020-02-25
DC.identifier	https://doi.org/10.1253/circj.CJ-19-0856
DC.subject	Hypothermia
	J wave
	Osborn wave
	Sudden cardiac death
	Ventricular arrhythmia
DC.description	Nobunaga Okada, Tasuku Matsuyama, Sachiko Morita, Naoki Ehara, Nobuhiro Miyamae, Yohei Okada, Takaaki Jo, Yasuyuki Sumida, Makoto Watanabe, Masahiro Nozawa, Ayumu Tsuruoka, Yoshihiro Fujimoto, Yoshiki Okumura, Kunio Hamanaka, Tetsuhisa Kitamura, Kei Nishiyama, Bon Ohta, Osborn Wave Is Related to Ventricular Fibrillation and Tachycardia in Hypothermic Patients, Circulation Journal, 2020, Volume 84, Issue 3, Pages 445-455, Released February 25, 2020, [Advance publication] Released January 30, 2020, Online ISSN 1347-4820, Print ISSN 1346-9843, https://doi.org/10.1253/circj.CJ-19-0856, https://www.jstage.jst.go.jp/article/circj/84/3/84_CJ-19-0856/_article/-char/en
DCTERMS.abstract	BACKGROUND: The Osborn wave (OW) is often observed in hypothermic patients; however, whether OW in hypothermic patients is related to the development of fatal ventricular arrhythmia, including ventricular fibrillation (VF) and pulseless ventricular tachycardia (VT), remains undetermined. This study aimed to estimate the association between OW and the incidence of fatal ventricular arrhythmias.Methods and Results: This retrospective study used the Japanese Accidental Hypothermia Network registry database and included 572 hypothermic patients. Patients were divided into the OW group (those with OW) and non-OW group (those without OW). The relationship between the development of fatal arrhythmias and presence of OW was assessed using the chi-squared test. All patients who developed VF/VT (n=10) had OW on electrocardiogram upon hospital arrival. The presence of OW had a sensitivity of 100%, specificity of 47.8%, positive predictive value of 4.0%, and negative predictive value of 100% for VF/VT development. The in-hospital mortality rate was 22.3% in the OW group and 21.2% in the non-OW group (P=0.781). CONCLUSIONS: OW was observed in all hypothermic patients with VF/VT. The occurrence of ventricular arrhythmias is highly unlikely in the absence of OW on the electrocardiogram. Although the presence of OW might be used to predict these fatal arrhythmias in hypothermic patients, there was no association between the presence of OW and in-hospital mortality.
DC.rights	© 2020 The Japanese Circulation Society. This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
DC.format	78716
citation_title	Osborn Wave Is Related to Ventricular Fibrillation and Tachycardia in Hypothermic Patients
citation_author	Okada, Nobunaga
	Matsuyama, Tasuku
	Morita, Sachiko
	Ehara, Naoki
	Miyamae, Nobuhiro
	Okada, Yohei
	Jo, Takaaki
	Sumida, Yasuyuki
	Watanabe, Makoto
	Nozawa, Masahiro
	Tsuruoka, Ayumu
	Fujimoto, Yoshihiro
	Okumura, Yoshiki
	Hamanaka, Kunio
	Kitamura, Tetsuhisa
	Nishiyama, Kei
	Ohta, Bon
citation_publisher	Japanese Circulation Society
citation_language	English
citation_date	2020-02-25
citation_journal_title	Circulation journal
citation_volume	84
citation_issue	3
citation_firstpage	445
citation_lastpage	455
citation_doi	https://doi.org/10.1253/circj.CJ-19-0856
citation_pmid	31996488
citation_public_url	https://hdl.handle.net/11094/78716

Osborn Wave Is Related to Ventricular Fibrillation and Tachycardia in Hypothermic Patients

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