Clinical impact of ventricular tachycardia and/or fibrillation during the acute phase of acute myocardial infarction on in-hospital and 5-year mortality rates in the percutaneous coronary intervention era

Masuda, Masaharu; Nakatani, Daisaku; Hikoso, Shungo; Suna, Shinichiro; Usami, Masaya; Matsumoto, Sen; Kitamura, Tetsuhisa; Minamiguchi, Hitoshi; Okuyama, Yuji; Uematsu, Masaaki; Yamada, Takahisa; Iwakura, Katsuomi; Hamasaki, Toshimitsu; Sakata, Yasuhiko; Sato, Hiroshi; Nanto, Shinsuke; Hori, Masatsugu; Komuro, Issei; Sakata, Yasushi

doi:https://doi.org/10.1253/circj.CJ-16-0183

Clinical impact of ventricular tachycardia and/or fibrillation during the acute phase of acute myocardial infarction on in-hospital and 5-year mortality rates in the percutaneous coronary intervention era

Masuda, Masaharu; Nakatani, Daisaku; Hikoso, Shungo et al.

Circulation Journal, 2016, 80(7), 1539-1547

Number of Access:425（2025-04-30 11:38 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/78930

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Title	Clinical impact of ventricular tachycardia and/or fibrillation during the acute phase of acute myocardial infarction on in-hospital and 5-year mortality rates in the percutaneous coronary intervention era
Creator	CreatorName Masuda, Masaharu
	NRID 1000060444535 1000060444535 researchmap permalink dsyma dsyma Scopus Author ID 6603545219 6603545219 CreatorName Nakatani, Daisaku
	NRID 1000030423164 1000030423164 researchmap permalink hikoso_osakauniv hikoso_osakauniv Scopus Author ID 6507288830 6507288830 CreatorName Hikoso, Shungo
	NRID 1000040573085 1000040573085 CreatorName Suna, Shinichiro
	CreatorName Usami, Masaya
	CreatorName Matsumoto, Sen
	NRID 1000030639810 1000030639810 ORCID 0000-0003-0107-0580 0000-0003-0107-0580 researchmap permalink Kitamura_T Kitamura_T Scopus Author ID 22234282700 22234282700 CreatorName Kitamura, Tetsuhisa
	NRID 1000090648495 1000090648495 CreatorName Minamiguchi, Hitoshi
	CreatorName Okuyama, Yuji
	CreatorName Uematsu, Masaaki
	CreatorName Yamada, Takahisa
	CreatorName Iwakura, Katsuomi
	NRID 1000040379243 1000040379243 CreatorName Hamasaki, Toshimitsu
	NRID 1000090379206 1000090379206 CreatorName Sakata, Yasuhiko
	NRID 1000010294092 1000010294092 CreatorName Sato, Hiroshi
	CreatorName Nanto, Shinsuke
	CreatorName Hori, Masatsugu
	NRID 1000030260483 1000030260483 CreatorName Komuro, Issei
	NRID 1000000397671 1000000397671 ORCID 0000-0002-5618-4721 0000-0002-5618-4721 researchmap permalink C4589 C4589 Scopus Author ID 35395964700 35395964700 CreatorName Sakata, Yasushi
Subject	Acute myocardial infarction
	Percutaneous coronary intervention
	Prognosis
	Ventricular fibrillation
	Ventricular tachycardia
Description	Masaharu Masuda, Daisaku Nakatani, Shungo Hikoso, Shinichiro Suna, Masaya Usami, Sen Matsumoto, Tetsuhisa Kitamura, Hitoshi Minamiguchi, Yuji Okuyama, Masaaki Uematsu, Takahisa Yamada, Katsuomi Iwakura, Toshimitsu Hamasaki, Yasuhiko Sakata, Hiroshi Sato, Shinsuke Nanto, Masatsugu Hori, Issei Komuro, Yasushi Sakata, on behalf of the OACIS investigators, Clinical Impact of Ventricular Tachycardia and/or Fibrillation During the Acute Phase of Acute Myocardial Infarction on In-Hospital and 5-Year Mortality Rates in the Percutaneous Coronary Intervention Era, Circulation Journal, 2016, Volume 80, Issue 7, Pages 1539-1547, Released June 24, 2016, [Advance publication] Released May 24, 2016, Online ISSN 1347-4820, Print ISSN 1346-9843, https://doi.org/10.1253/circj.CJ-16-0183, https://www.jstage.jst.go.jp/article/circj/80/7/80_CJ-16-0183/_article/-char/en
Abstract	Background: The aim of this study was to investigate the prognostic impact of acute-phase ventricular tachycardia and fibrillation (VT/VF) on ST-segment elevation myocardial infarction (STEMI) patients in the percutaneous coronary intervention (PCI) era. Methods and Results: Using the database of the Osaka Acute Coronary Insufficiency Study (OACIS), we studied 4,283 consecutive patients with STEMI who were hospitalized within 12 h of STEMI onset and underwent emergency PCI. Acute-phase VT/VF, defined as ≥3 consecutive ventricular premature complexes and/or VF within the 1st week of hospitalization, occurred in 997 (23.3%) patients. In-hospital mortality risk was significantly higher in patients with acute-phase VT/VF than inthose without (14.6% vs. 4.3%, adjusted hazard ratio (HR) 1.83, P=0.0013). Among patients discharged alive, 5-year mortality rates were comparable between patients with and without acute-phase VT/VF. Subgroup analysis showed that acute-phase VT/VF was associated with increased 5-year mortality after discharge in high-risk patients (GRACE Risk Score ≥115, adjusted HR 1.60, P=0.043), but not in intermediate- or low-risk patients. Conclusions: Even in the PCI era, acute-phase VT/VF was associated with higher in-hospital deaths of STEMI patients. However, the 5-year prognostic impact of acute-phase VT/VF was limited to high-risk patients.
Publisher	Japanese Circulation Society
Source Title	Circulation Journal
Volume (Issue)	80(7)
Page	1539-1547
Date of Issued	2016-06-24
Language	English
Handle URL	https://hdl.handle.net/11094/78930
PISSN	13469843
eISSN	13474820
NCID	AA11591968
Relation.isIdenticalTo	DOI (Publisher Version) https://doi.org/10.1253/circj.CJ-16-0183
Relation.isIdenticalTo	PMID 27238618
Access Rights	open access
oaire:version	Version of Record
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCTERMS.bibliographicCitation	Circulation Journal. 2016, 80(7), p. 1539-1547
DC.title	Clinical impact of ventricular tachycardia and/or fibrillation during the acute phase of acute myocardial infarction on in-hospital and 5-year mortality rates in the percutaneous coronary intervention era
DC.creator	Masuda, Masaharu
	Nakatani, Daisaku
	Hikoso, Shungo
	Suna, Shinichiro
	Usami, Masaya
	Matsumoto, Sen
	Kitamura, Tetsuhisa
	Minamiguchi, Hitoshi
	Okuyama, Yuji
	Uematsu, Masaaki
	Yamada, Takahisa
	Iwakura, Katsuomi
	Hamasaki, Toshimitsu
	Sakata, Yasuhiko
	Sato, Hiroshi
	Nanto, Shinsuke
	Hori, Masatsugu
	Komuro, Issei
	Sakata, Yasushi
DC.publisher	Japanese Circulation Society
DC.language' scheme='DCTERMS.RFC1766	English
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2016-06-24
DC.identifier	https://doi.org/10.1253/circj.CJ-16-0183
DC.subject	Acute myocardial infarction
	Percutaneous coronary intervention
	Prognosis
	Ventricular fibrillation
	Ventricular tachycardia
DC.description	Masaharu Masuda, Daisaku Nakatani, Shungo Hikoso, Shinichiro Suna, Masaya Usami, Sen Matsumoto, Tetsuhisa Kitamura, Hitoshi Minamiguchi, Yuji Okuyama, Masaaki Uematsu, Takahisa Yamada, Katsuomi Iwakura, Toshimitsu Hamasaki, Yasuhiko Sakata, Hiroshi Sato, Shinsuke Nanto, Masatsugu Hori, Issei Komuro, Yasushi Sakata, on behalf of the OACIS investigators, Clinical Impact of Ventricular Tachycardia and/or Fibrillation During the Acute Phase of Acute Myocardial Infarction on In-Hospital and 5-Year Mortality Rates in the Percutaneous Coronary Intervention Era, Circulation Journal, 2016, Volume 80, Issue 7, Pages 1539-1547, Released June 24, 2016, [Advance publication] Released May 24, 2016, Online ISSN 1347-4820, Print ISSN 1346-9843, https://doi.org/10.1253/circj.CJ-16-0183, https://www.jstage.jst.go.jp/article/circj/80/7/80_CJ-16-0183/_article/-char/en
DCTERMS.abstract	Background: The aim of this study was to investigate the prognostic impact of acute-phase ventricular tachycardia and fibrillation (VT/VF) on ST-segment elevation myocardial infarction (STEMI) patients in the percutaneous coronary intervention (PCI) era. Methods and Results: Using the database of the Osaka Acute Coronary Insufficiency Study (OACIS), we studied 4,283 consecutive patients with STEMI who were hospitalized within 12 h of STEMI onset and underwent emergency PCI. Acute-phase VT/VF, defined as ≥3 consecutive ventricular premature complexes and/or VF within the 1st week of hospitalization, occurred in 997 (23.3%) patients. In-hospital mortality risk was significantly higher in patients with acute-phase VT/VF than inthose without (14.6% vs. 4.3%, adjusted hazard ratio (HR) 1.83, P=0.0013). Among patients discharged alive, 5-year mortality rates were comparable between patients with and without acute-phase VT/VF. Subgroup analysis showed that acute-phase VT/VF was associated with increased 5-year mortality after discharge in high-risk patients (GRACE Risk Score ≥115, adjusted HR 1.60, P=0.043), but not in intermediate- or low-risk patients. Conclusions: Even in the PCI era, acute-phase VT/VF was associated with higher in-hospital deaths of STEMI patients. However, the 5-year prognostic impact of acute-phase VT/VF was limited to high-risk patients.
DC.format	78930
citation_title	Clinical impact of ventricular tachycardia and/or fibrillation during the acute phase of acute myocardial infarction on in-hospital and 5-year mortality rates in the percutaneous coronary intervention era
citation_author	Masuda, Masaharu
	Nakatani, Daisaku
	Hikoso, Shungo
	Suna, Shinichiro
	Usami, Masaya
	Matsumoto, Sen
	Kitamura, Tetsuhisa
	Minamiguchi, Hitoshi
	Okuyama, Yuji
	Uematsu, Masaaki
	Yamada, Takahisa
	Iwakura, Katsuomi
	Hamasaki, Toshimitsu
	Sakata, Yasuhiko
	Sato, Hiroshi
	Nanto, Shinsuke
	Hori, Masatsugu
	Komuro, Issei
	Sakata, Yasushi
citation_publisher	Japanese Circulation Society
citation_language	English
citation_date	2016-06-24
citation_journal_title	Circulation Journal
citation_volume	80
citation_issue	7
citation_firstpage	1539
citation_lastpage	1547
citation_doi	https://doi.org/10.1253/circj.CJ-16-0183
citation_pmid	27238618
citation_public_url	https://hdl.handle.net/11094/78930

Clinical impact of ventricular tachycardia and/or fibrillation during the acute phase of acute myocardial infarction on in-hospital and 5-year mortality rates in the percutaneous coronary intervention era

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