Highly sensitive spectral interferometric fourwave mixing microscopy near the shot noise limit and its combination with two-photon excited fluorescence microscopy

Isobe, Keisuke; Ozeki, Yasuyuki; Kawasumi, Takehito et al.

Optics Express, 2006, 14(23), 11204-11214

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Identifier to cite or link to this item: https://hdl.handle.net/11094/79047

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Title
Highly sensitive spectral interferometric fourwave mixing microscopy near the shot noise limit and its combination with two-photon excited fluorescence microscopy
Creator
CreatorName
Isobe, Keisuke
NRID
1000060437374 1000060437374
CreatorName
Ozeki, Yasuyuki
CreatorName
Kawasumi, Takehito
CreatorName
Kataoka, Shogo
NRID
1000020243496 1000020243496
CreatorName
Kajiyama, Shin'ichiro
NRID
1000000311770 1000000311770
researchmap permalink
read0068600 read0068600
CreatorName
Fukui, Kiichi
NRID
1000080113520 1000080113520
CreatorName
Itoh, Kazuyoshi
Description
Isobe K., Ozeki Y., Kawasumi T., et al. Highly sensitive spectral interferometric fourwave mixing microscopy near the shot noise limit and its combination with two-photon excited fluorescence microscopy. Optics Express, 14, 23, 11204. https://doi.org/10.1364/OE.14.011204.
Abstract
We present spectral interferometric four-wave mixing (FWM) microscopy with a nearly shot-noise limited sensitivity and with the capability of separating FWM signals from fluorescence signals. We analyze the requirements for obtaining the shot-noise limited sensitivity and experimentally achieve the sensitivity that is only 4-dB lower than the shotnoise limit. Moreover, we show that only FWM signals can be extracted through the Fourier filtering even when the FWM spectrum is overlapped and overwhelmed by the fluorescence spectrum. We demonstrate simultaneous acquisition of FWM and two-photon excited fluorescence images of fluorescent monodispersed polystyrene microspheres.
Publisher
Optical Society of American
Source Title
Optics Express
Volume (Issue)
14(23)
Page
11204-11214
Date of Issued
2006-11-13
Language
English
Handle URL
https://hdl.handle.net/11094/79047
eISSN
10944087
Relation.isIdenticalTo
DOI (Publisher Version)
https://doi.org/10.1364/OE.14.011204
Access Rights
open access
CopyRight
©2006 Optical Society of America. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.
oaire:version
Version of Record
Category
学術雑誌論文 Journal Article