Multichannel wireless-electrodeless quartz-crystal microbalance immunosensor

Ogi, Hirotsugu; Nagai, Hironao; Fukunishi, Yuji; Yanagida, Taiji; Hirao, Masahiko; Nishiyama, Masayoshi

doi:https://doi.org/10.1021/ac100527r

Multichannel wireless-electrodeless quartz-crystal microbalance immunosensor

Ogi, Hirotsugu; Nagai, Hironao; Fukunishi, Yuji et al.

Analytical Chemistry, 2010, 82(9), 3957-3962

Number of Access:571（2025-08-14 23:46 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/84137

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Title	Multichannel wireless-electrodeless quartz-crystal microbalance immunosensor
Creator	NRID 1000090252626 1000090252626 researchmap permalink read0042771 read0042771 Scopus Author ID 35563683500 35563683500 CreatorName Ogi, Hirotsugu
	CreatorName Nagai, Hironao
	CreatorName Fukunishi, Yuji
	CreatorName Yanagida, Taiji
	NRID 1000080112027 1000080112027 CreatorName Hirao, Masahiko
	CreatorName Nishiyama, Masayoshi
Description	Hirotsugu Ogi, Hironao Nagai, Yuji Fukunishi, Taiji Yanagda, Masahiko Hirao, and Masayoshi Nishiyama. Multichannel wireless-electrodeless quartz-crystal microbalance immunosensor. Analytical Chemistry, 2010, 82(9), 3957-3962. ©2010 American Chemical Society. https://doi.org/10.1021/ac100527r.
Abstract	We develop the wireless-electrodeless multichannel quartz-crystal microbalance (QCM) biosensor using quartz plates of slightly different thicknesses. Their shear vibrations are simultaneously excited and detected by a pair of antenna wires to perform the noncontacting measurement. Their fundamental resonance frequencies are between 43 and 55 MHz, and vibrations at up to 10 channels are measured in liquids. Owing to high affinity of naked quartz surfaces for proteins, we immobilized various receptor proteins on different quartz plates nonspecifically and detected various antigen-antibody reactions separately. The exponential coefficient of the frequency change, rather than the amount of the frequency decrease, is found to be useful for distinguishing between specific and nonspecific binding reactions.
Publisher	American Chemical Society
Source Title	Analytical Chemistry
Volume (Issue)	82(9)
Page	3957-3962
Date of Issued	2010-05-01
Language	English
Handle URL	https://hdl.handle.net/11094/84137
PISSN	00032700
eISSN	15206882
NCID	AA00524878
Relation.isVersionOf	DOI (Publisher Version) https://doi.org/10.1021/ac100527r
Relation.isIdenticalTo	PMID 20387824
Access Rights	open access
CopyRight	This document is the Accepted Manuscript version of a Published Work that appeared in final form in Analytical Chemistry, © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/ac100527r.
oaire:version	Accepted Manuscript
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCMI Type	Text
DCTERMS.bibliographicCitation	Analytical Chemistry. 2010, 82(9), p. 3957-3962
DC.title	Multichannel wireless-electrodeless quartz-crystal microbalance immunosensor
DC.creator	Ogi, Hirotsugu
	Nagai, Hironao
	Fukunishi, Yuji
	Yanagida, Taiji
	Hirao, Masahiko
	Nishiyama, Masayoshi
DC.publisher	American Chemical Society
DC.language' scheme='DCTERMS.RFC1766	English
DC.type' scheme='DCTERMS.DCMIType	Text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2010-05-01
DC.identifier	https://doi.org/10.1021/ac100527r
DC.description	Hirotsugu Ogi, Hironao Nagai, Yuji Fukunishi, Taiji Yanagda, Masahiko Hirao, and Masayoshi Nishiyama. Multichannel wireless-electrodeless quartz-crystal microbalance immunosensor. Analytical Chemistry, 2010, 82(9), 3957-3962. ©2010 American Chemical Society. https://doi.org/10.1021/ac100527r.
DCTERMS.abstract	We develop the wireless-electrodeless multichannel quartz-crystal microbalance (QCM) biosensor using quartz plates of slightly different thicknesses. Their shear vibrations are simultaneously excited and detected by a pair of antenna wires to perform the noncontacting measurement. Their fundamental resonance frequencies are between 43 and 55 MHz, and vibrations at up to 10 channels are measured in liquids. Owing to high affinity of naked quartz surfaces for proteins, we immobilized various receptor proteins on different quartz plates nonspecifically and detected various antigen-antibody reactions separately. The exponential coefficient of the frequency change, rather than the amount of the frequency decrease, is found to be useful for distinguishing between specific and nonspecific binding reactions.
DC.rights	This document is the Accepted Manuscript version of a Published Work that appeared in final form in Analytical Chemistry, © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/ac100527r.
DC.format	84137
citation_title	Multichannel wireless-electrodeless quartz-crystal microbalance immunosensor
citation_author	Ogi, Hirotsugu
	Nagai, Hironao
	Fukunishi, Yuji
	Yanagida, Taiji
	Hirao, Masahiko
	Nishiyama, Masayoshi
citation_publisher	American Chemical Society
citation_language	English
citation_date	2010-05-01
citation_journal_title	Analytical Chemistry
citation_volume	82
citation_issue	9
citation_firstpage	3957
citation_lastpage	3962
citation_doi	https://doi.org/10.1021/ac100527r
citation_pmid	20387824
citation_public_url	https://hdl.handle.net/11094/84137

Multichannel wireless-electrodeless quartz-crystal microbalance immunosensor

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