自己組織化ナノ細孔を形成したSUS316Lステンレス鋼の薬剤徐放性

宮部, さやか; 藤永, 悠志; 土谷, 博昭 他

スマートプロセス学会誌, 2021, 10(4), 256-260

Number of Access:1,207（2025-08-14 02:03 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/88670

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Title
自己組織化ナノ細孔を形成したSUS316Lステンレス鋼の薬剤徐放性
Drug Release Characteristic of Type 316L Stainless Steel with Self-Organized Nanopores
ジコ　ソシキ　カ　ナノ　サイコウ　ヲ　ケイセイ　シタ　SUS316L　ステンレス　コウ　ノ　ヤクザイ　ジョホウ　セイ
Creator
NRID
1000050584132 1000050584132
researchmap permalink
read0151100 read0151100
Scopus Author ID
16239274400 16239274400
CreatorName
宮部, さやか ; ミヤベ, サヤカ ; Miyabe, Sayaka
CreatorName
藤永, 悠志 ; フジナガ, ユウシ ; Fujinaga, Yushi
NRID
1000050432513 1000050432513
ORCID
0000-0001-5619-0139 0000-0001-5619-0139
researchmap permalink
read0076368 read0076368
Scopus Author ID
7202203364 7202203364
CreatorName
土谷, 博昭 ; ツチヤ, ヒロアキ ; Tsuchiya, Hiroaki
NRID
1000070199371 1000070199371
ORCID
0000-0002-7787-4190 0000-0002-7787-4190
researchmap permalink
read0013980 read0013980
Scopus Author ID
57211614674 57211614674
CreatorName
藤本, 慎司 ; フジモト, シンジ ; Fujimoto, Shinji
Subject
Local Drug Delivery System
Anodic Polarization
Nanopore
Nanostructure
Biomaterials
Abstract
Drug-releasing implants are attracting attention as a local drug delivery system（LDDS）with high drug efficiency and few side effects because they can administer drugs locally and continuously. Since the surface structure of implants is important for drug- releasing implants, many research reports have been made using metallic surfaces with nanostructures such as TiO 2 nanotubes as the platform for LDDS. In present study, we investigated drug release characteristic of collagen coated Type 316L stainless steel with self-organized nanopores formed by anodic polarization. Regardless of whether or not nanopore structure, the collagen coating treatment increased the amount of drug loaded on samples. The samples with nanopore structure suppressed burst release and increased the rate of slow release.
Publisher
スマートプロセス学会
Smart Processing Society for Materials, Environment & Energy
Source Title
スマートプロセス学会誌
Volume (Issue)
10(4)
Page
256-260
Date of Issued
2021
Language
Japanese
Handle URL
https://hdl.handle.net/11094/88670
PISSN
2186702X
eISSN
21871337
NCID
AA12553487
Relation.isIdenticalTo
DOI (Publisher Version)
https://doi.org/10.7791/jspmee.10.256
Access Rights
open access
oaire:version
Version of Record
Category
学術雑誌論文 Journal Article