Titanium as an Instant Adhesive for Biological Soft Tissue

Okada, Masahiro; Hara, Emilio Satoshi; Yabe, Atsushi; Okada, Kei; Shibata, Yo; Torii, Yasuhiro; Nakano, Takayoshi; Matsumoto, Takuya

doi:https://doi.org/10.1002/admi.201902089

Titanium as an Instant Adhesive for Biological Soft Tissue

Okada, Masahiro; Hara, Emilio Satoshi; Yabe, Atsushi et al.

Advanced Materials Interfaces, 2020, 7(9), 1902089

Number of Access:980（2025-08-21 04:37 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/89806

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Title	Titanium as an Instant Adhesive for Biological Soft Tissue
Creator	NRID 1000070416220 1000070416220 CreatorName Okada, Masahiro
	NRID 1000040779443 1000040779443 CreatorName Hara, Emilio Satoshi
	CreatorName Yabe, Atsushi
	CreatorName Okada, Kei
	NRID 1000030327936 1000030327936 CreatorName Shibata, Yo
	NRID 1000010188831 1000010188831 CreatorName Torii, Yasuhiro
	NRID 1000030243182 1000030243182 ORCID 0000-0001-8052-1698 0000-0001-8052-1698 researchmap permalink read0013987 read0013987 Scopus Author ID 7403896013 7403896013 CreatorName Nakano, Takayoshi
	NRID 1000040324793 1000040324793 CreatorName Matsumoto, Takuya
Description	Okada M., Hara E.S., Yabe A., et al. Titanium as an Instant Adhesive for Biological Soft Tissue. Advanced Materials Interfaces, 7, 9, 1902089. https://doi.org/10.1002/admi.201902089.
Abstract	A variety of polymer- and ceramic-based soft-tissue adhesives have been developed as alternatives to surgical sutures, yet several disadvantages regarding the mechanical properties, biocompatibility, and handling hinder their further application particularly when applied for immobilization of implantable devices. Here, it is reported that a biocompatible and tough metal, titanium (Ti), shows instant and remarkable adhesion properties after acid treatment, demonstrated by ex vivo shear adhesion tests with mouse dermal tissues. Importantly, in vivo experiments demonstrate that the acid-treated Ti can easily and stably immobilize a device implanted in the mouse subcutaneous tissue. Collectively, the acid-treated Ti is shown as a solid-state instant adhesive material for biological soft tissues, which can have diverse applications including immobilization of body-implantable devices.
Publisher	Wiley-VCH
Source Title	Advanced Materials Interfaces
Volume (Issue)	7(9)
Page	1902089
Date of Issued	2020-05-07
Language	English
Handle URL	https://hdl.handle.net/11094/89806
eISSN	21967350
Relation.isIdenticalTo	DOI (Publisher Version) https://doi.org/10.1002/admi.201902089
Access Rights	open access
CopyRight	This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
oaire:version	Version of Record
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCMI Type	Text
DCTERMS.bibliographicCitation	Advanced Materials Interfaces. 2020, 7(9), p. 1902089
DC.title	Titanium as an Instant Adhesive for Biological Soft Tissue
DC.creator	Okada, Masahiro
	Hara, Emilio Satoshi
	Yabe, Atsushi
	Okada, Kei
	Shibata, Yo
	Torii, Yasuhiro
	Nakano, Takayoshi
	Matsumoto, Takuya
DC.publisher	Wiley-VCH
DC.language' scheme='DCTERMS.RFC1766	English
DC.type' scheme='DCTERMS.DCMIType	Text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2020-05-07
DC.identifier	https://doi.org/10.1002/admi.201902089
DC.description	Okada M., Hara E.S., Yabe A., et al. Titanium as an Instant Adhesive for Biological Soft Tissue. Advanced Materials Interfaces, 7, 9, 1902089. https://doi.org/10.1002/admi.201902089.
DCTERMS.abstract	A variety of polymer- and ceramic-based soft-tissue adhesives have been developed as alternatives to surgical sutures, yet several disadvantages regarding the mechanical properties, biocompatibility, and handling hinder their further application particularly when applied for immobilization of implantable devices. Here, it is reported that a biocompatible and tough metal, titanium (Ti), shows instant and remarkable adhesion properties after acid treatment, demonstrated by ex vivo shear adhesion tests with mouse dermal tissues. Importantly, in vivo experiments demonstrate that the acid-treated Ti can easily and stably immobilize a device implanted in the mouse subcutaneous tissue. Collectively, the acid-treated Ti is shown as a solid-state instant adhesive material for biological soft tissues, which can have diverse applications including immobilization of body-implantable devices.
DC.rights	This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
DC.format	89806
citation_title	Titanium as an Instant Adhesive for Biological Soft Tissue
citation_author	Okada, Masahiro
	Hara, Emilio Satoshi
	Yabe, Atsushi
	Okada, Kei
	Shibata, Yo
	Torii, Yasuhiro
	Nakano, Takayoshi
	Matsumoto, Takuya
citation_publisher	Wiley-VCH
citation_language	English
citation_date	2020-05-07
citation_journal_title	Advanced Materials Interfaces
citation_volume	7
citation_issue	9
citation_firstpage	1902089
citation_doi	https://doi.org/10.1002/admi.201902089
citation_public_url	https://hdl.handle.net/11094/89806

Titanium as an Instant Adhesive for Biological Soft Tissue

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