Development of non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys for metallic biomaterials

Hori, Tetsuya; Nagase, Takeshi; Todai, Mitsuharu; Matsugaki, Aira; Nakano, Takayoshi

doi:https://doi.org/10.1016/j.scriptamat.2019.07.011

Development of non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys for metallic biomaterials

Hori, Tetsuya; Nagase, Takeshi; Todai, Mitsuharu et al.

Scripta Materialia, 2019, 172, 83-87

Number of Access:634（2025-07-27 16:05 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/89812

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Title	Development of non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys for metallic biomaterials
Creator	NRID 1000070550078 1000070550078 researchmap permalink thori567 thori567 Scopus Author ID 7402411497 7402411497 CreatorName Hori, Tetsuya
	NRID 1000050362661 1000050362661 CreatorName Nagase, Takeshi
	NRID 1000010610800 1000010610800 CreatorName Todai, Mitsuharu
	NRID 1000010592529 1000010592529 ORCID 0000-0002-8427-7124 0000-0002-8427-7124 researchmap permalink aira aira Scopus Author ID 24172720900 24172720900 CreatorName Matsugaki, Aira
	NRID 1000030243182 1000030243182 ORCID 0000-0001-8052-1698 0000-0001-8052-1698 researchmap permalink read0013987 read0013987 Scopus Author ID 7403896013 7403896013 CreatorName Nakano, Takayoshi
Subject	Biocompatibility
	Biomaterials
	High-entropy alloys
	Solidification
	Thermodynamic calculation
Description	Hori T., Nagase T., Todai M., et al. Development of non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys for metallic biomaterials. Scripta Materialia, 172, , 83. https://doi.org/10.1016/j.scriptamat.2019.07.011.
Abstract	Nobel non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys (HEAs) for metallic biomaterials (bio-HEAs) were designed and developed. The pseudo-binary phase diagrams focusing on solidification were constructed by thermodynamic calculations. The shifting the alloy composition of the equiatomic TiNbTaZrMo bio-HEA can realize the drastic improvement of the deformability. Notably, the non-equiatomic Ti, Zr-rich composition stimulated the molecular interaction between biological cells and bio-HEA, indicating the possibility of the proposed non-equiatomic Ti-Nb-Ta-Zr-Mo HEAs as an advanced biomaterial for bone tissue engineering applications. This is the first achievement for the alloy design including the control of alloy composition for the development of new bio-HEAs.
Publisher	Acta Materialia Inc.
Source Title	Scripta Materialia
Volume (Issue)	172
Page	83-87
Date of Issued	2019-11-01
Language	English
Handle URL	https://hdl.handle.net/11094/89812
PISSN	13596462
NCID	AA11067905
Relation.isIdenticalTo	DOI (Publisher Version) https://doi.org/10.1016/j.scriptamat.2019.07.011
Access Rights	open access
CopyRight	This article is licensed under a Creative Commons Attribution 4.0 International License.
oaire:version	Version of Record
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCMI Type	Text
DCTERMS.bibliographicCitation	Scripta Materialia. 2019, 172, p. 83-87
DC.title	Development of non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys for metallic biomaterials
DC.creator	Hori, Tetsuya
	Nagase, Takeshi
	Todai, Mitsuharu
	Matsugaki, Aira
	Nakano, Takayoshi
DC.publisher	Acta Materialia Inc.
DC.language' scheme='DCTERMS.RFC1766	English
DC.type' scheme='DCTERMS.DCMIType	Text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2019-11-01
DC.identifier	https://doi.org/10.1016/j.scriptamat.2019.07.011
DC.subject	Biocompatibility
	Biomaterials
	High-entropy alloys
	Solidification
	Thermodynamic calculation
DC.description	Hori T., Nagase T., Todai M., et al. Development of non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys for metallic biomaterials. Scripta Materialia, 172, , 83. https://doi.org/10.1016/j.scriptamat.2019.07.011.
DCTERMS.abstract	Nobel non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys (HEAs) for metallic biomaterials (bio-HEAs) were designed and developed. The pseudo-binary phase diagrams focusing on solidification were constructed by thermodynamic calculations. The shifting the alloy composition of the equiatomic TiNbTaZrMo bio-HEA can realize the drastic improvement of the deformability. Notably, the non-equiatomic Ti, Zr-rich composition stimulated the molecular interaction between biological cells and bio-HEA, indicating the possibility of the proposed non-equiatomic Ti-Nb-Ta-Zr-Mo HEAs as an advanced biomaterial for bone tissue engineering applications. This is the first achievement for the alloy design including the control of alloy composition for the development of new bio-HEAs.
DC.rights	This article is licensed under a Creative Commons Attribution 4.0 International License.
DC.format	89812
citation_title	Development of non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys for metallic biomaterials
citation_author	Hori, Tetsuya
	Nagase, Takeshi
	Todai, Mitsuharu
	Matsugaki, Aira
	Nakano, Takayoshi
citation_publisher	Acta Materialia Inc.
citation_language	English
citation_date	2019-11-01
citation_journal_title	Scripta Materialia
citation_volume	172
citation_firstpage	83
citation_lastpage	87
citation_doi	https://doi.org/10.1016/j.scriptamat.2019.07.011
citation_public_url	https://hdl.handle.net/11094/89812

Development of non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys for metallic biomaterials

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