A case of fulminant amoebic colitis during systemic chemotherapy for gastric cancer

Takiguchi, Nobuo; Hata, Tsuyoshi; Saito, Takuro; Sekido, Yuki; Hamabe, Atsushi; Ogino, Takayuki; Miyoshi, Norikatsu; Uemura, Mamoru; Doki, Yuichiro; Eguchi, Hidetoshi

doi:https://doi.org/10.1007/s12328-023-01835-5

A case of fulminant amoebic colitis during systemic chemotherapy for gastric cancer

Takiguchi, Nobuo; Hata, Tsuyoshi; Saito, Takuro et al.

Clinical Journal of Gastroenterology, 2023, 348, 1565

Number of Access:1,811（2025-08-13 23:45 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/92445

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Title	A case of fulminant amoebic colitis during systemic chemotherapy for gastric cancer
Creator	CreatorName Takiguchi, Nobuo
	NRID 1000080749747 1000080749747 researchmap permalink tsuyoshi_hata tsuyoshi_hata Scopus Author ID 57189996374 57189996374 CreatorName Hata, Tsuyoshi
	NRID 1000020646468 1000020646468 researchmap permalink tsaito19 tsaito19 Scopus Author ID 57211629912 57211629912 CreatorName Saito, Takuro
	NRID 1000000781709 1000000781709 researchmap permalink 00781709 00781709 Scopus Author ID 57193691322 57193691322 CreatorName Sekido, Yuki
	NRID 1000060621034 1000060621034 ORCID 0000-0001-5535-3514 0000-0001-5535-3514 researchmap permalink hamabe_atsushi hamabe_atsushi CreatorName Hamabe, Atsushi
	NRID 1000050597458 1000050597458 researchmap permalink togino04 togino04 Scopus Author ID 57200254430 57200254430 CreatorName Ogino, Takayuki
	NRID 1000020528624 1000020528624 researchmap permalink nor nor Scopus Author ID 9242781300 9242781300 CreatorName Miyoshi, Norikatsu
	NRID 1000010528483 1000010528483 ORCID 0000-0001-6285-5619 0000-0001-6285-5619 researchmap permalink mamoruuemura mamoruuemura Scopus Author ID 36796497400 36796497400 CreatorName Uemura, Mamoru
	NRID 1000020291445 1000020291445 researchmap permalink ydoki3251 ydoki3251 Scopus Author ID 7006390687 7006390687 CreatorName Doki, Yuichiro
	NRID 1000090542118 1000090542118 researchmap permalink abcdabcdabcd abcdabcdabcd Scopus Author ID 7101627772 7101627772 CreatorName Eguchi, Hidetoshi
Subject	Amoebic colitis
	Chemotherapy
	Gastric cancer
	Colonoscopy
Description	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s12328-023-01835-5
Abstract	Amoebiasis is a parasitic infection caused by the protozoan, Entamoeba histolytica. At times, amoebiasis is activated under immunosuppressive conditions such as chemotherapy. We report a case of fulminant amoebic colitis resulting from an asymptomatic Entamoeba histolytica infection, which was activated by chemotherapy for gastric cancer. The patient developed diarrhea and fever after three courses of chemotherapy for gastric cancer and was diagnosed with acute enteritis. A colonoscopy and biopsy were performed because of the bloody stool. Histopathological findings revealed amoebic invasion of the rectum. Therefore, the patient was diagnosed with amoebic colitis and was treated with metronidazole. Emergency surgery was performed because intestinal perforation was suspected after which his general condition improved and was discharged. Subsequently, gastric cancer surgery was performed and the patient was discharged without postoperative complications. Hence, amoebic colitis should be listed as a differential diagnosis, and a colonoscopic biopsy should be performed when colitis occurs during chemotherapy for cancer.
Publisher	Springer Science and Business Media LLC
Source Title	Clinical Journal of Gastroenterology
Volume (Issue)	348
Page	1565
Date of Issued	2023-08-16
Language	English
Handle URL	https://hdl.handle.net/11094/92445
PISSN	18657257
eISSN	18657265
NCID	AA12646624
Relation.isVersionOf	DOI (Publisher Version) https://doi.org/10.1007/s12328-023-01835-5
Access Rights	open access
CopyRight	This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
oaire:version	Accepted Manuscript
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCMI Type	Text
DCTERMS.bibliographicCitation	Clinical Journal of Gastroenterology. 2023, 348, p. 1565
DC.title	A case of fulminant amoebic colitis during systemic chemotherapy for gastric cancer
DC.creator	Takiguchi, Nobuo
	Hata, Tsuyoshi
	Saito, Takuro
	Sekido, Yuki
	Hamabe, Atsushi
	Ogino, Takayuki
	Miyoshi, Norikatsu
	Uemura, Mamoru
	Doki, Yuichiro
	Eguchi, Hidetoshi
DC.publisher	Springer Science and Business Media LLC
DC.language' scheme='DCTERMS.RFC1766	English
DC.type' scheme='DCTERMS.DCMIType	Text
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2023-08-16
DC.identifier	https://doi.org/10.1007/s12328-023-01835-5
DC.subject	Amoebic colitis
	Chemotherapy
	Gastric cancer
	Colonoscopy
DC.description	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s12328-023-01835-5
DCTERMS.abstract	Amoebiasis is a parasitic infection caused by the protozoan, Entamoeba histolytica. At times, amoebiasis is activated under immunosuppressive conditions such as chemotherapy. We report a case of fulminant amoebic colitis resulting from an asymptomatic Entamoeba histolytica infection, which was activated by chemotherapy for gastric cancer. The patient developed diarrhea and fever after three courses of chemotherapy for gastric cancer and was diagnosed with acute enteritis. A colonoscopy and biopsy were performed because of the bloody stool. Histopathological findings revealed amoebic invasion of the rectum. Therefore, the patient was diagnosed with amoebic colitis and was treated with metronidazole. Emergency surgery was performed because intestinal perforation was suspected after which his general condition improved and was discharged. Subsequently, gastric cancer surgery was performed and the patient was discharged without postoperative complications. Hence, amoebic colitis should be listed as a differential diagnosis, and a colonoscopic biopsy should be performed when colitis occurs during chemotherapy for cancer.
DC.rights	This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
DC.format	92445
citation_title	A case of fulminant amoebic colitis during systemic chemotherapy for gastric cancer
citation_author	Takiguchi, Nobuo
	Hata, Tsuyoshi
	Saito, Takuro
	Sekido, Yuki
	Hamabe, Atsushi
	Ogino, Takayuki
	Miyoshi, Norikatsu
	Uemura, Mamoru
	Doki, Yuichiro
	Eguchi, Hidetoshi
citation_publisher	Springer Science and Business Media LLC
citation_language	English
citation_date	2023-08-16
citation_journal_title	Clinical Journal of Gastroenterology
citation_volume	348
citation_firstpage	1565
citation_doi	https://doi.org/10.1007/s12328-023-01835-5
citation_public_url	https://hdl.handle.net/11094/92445

A case of fulminant amoebic colitis during systemic chemotherapy for gastric cancer

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