Mechanical properties of computer-aided design/computer-aided manufacturing resin composites assuming perfect silane coupling using in silico homogenization of cryo-electron microscopy images

Lee, Chunwoo; Yamaguchi, Satoshi; Ohta, Keisuke et al.

Journal of Prosthodontic Research, 2019, 63(1), 90-94

Number of Access:615（2025-08-14 15:06 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/93095

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Title
Mechanical properties of computer-aided design/computer-aided manufacturing resin composites assuming perfect silane coupling using in silico homogenization of cryo-electron microscopy images
Creator
CreatorName
Lee, Chunwoo
NRID
1000030397773 1000030397773
ORCID
0000-0002-4661-8821 0000-0002-4661-8821
researchmap permalink
YamaguchiS_30397773 YamaguchiS_30397773
Scopus Author ID
7403873463 7403873463
CreatorName
Yamaguchi, Satoshi
NRID
1000000258401 1000000258401
CreatorName
Ohta, Keisuke
NRID
1000080243244 1000080243244
ORCID
0000-0003-3655-4809 0000-0003-3655-4809
researchmap permalink
read0014210 read0014210
Scopus Author ID
55994423600 55994423600
CreatorName
Imazato, Satoshi
Subject
CAD/CAM resin composite block
Cryo-electron microscopy
Finite element analysis
Silane coupling
Description
Lee C., Yamaguchi S., Ohta K., et al. Mechanical properties of computer-aided design/computer-aided manufacturing resin composites assuming perfect silane coupling using in silico homogenization of cryo-electron microscopy images. Journal of Prosthodontic Research 63, 90 (2019); https://doi.org/10.1016/j.jpor.2018.09.001.
Abstract
Purpose: The aim of this study was to determine the mechanical properties of computer-aided design/computer-aided manufacturing (CAD/CAM) resin composites for dental restoration assuming perfect silane coupling by in silico homogenization analysis using a three-dimensional model constructed from cryo-electron microscopy (cryo-EM) images. Methods: Three-dimensional dataset of a commercial CAD/CAM resin composite block (RCB) was obtained using EM with cryo-stage and focused ion beam at −130 °C. The region of inspection was 1.8 μm × 1.4 μm × 1.2 μm, and 213 slices were obtained from this region. Each slice was processed (noise reduction, threshold setting, and segmentation) using image processing software to design an in silico model. From the processed image slices, a bulk three-dimensional object and stereolithography model were reconstructed using voxel modeling software. To evaluate the elastic modulus and Poisson's ratio of the CAD/CAM RCB, homogenization analysis was performed. Results: The generated voxel model included 37,276,216 voxels, 42,472,040 patches of the surface, 2,123,672 nodes, a volume of 165,748,899, and a surface area of 175,206,723. The mean of the elastic moduli along each axis was 10.71 ± 1.79 GPa. The mean of the Poisson's ratios of each plane was 0.23 ± 0.02. Conclusions: A CAD/CAM resin composite model was successfully reconstructed from cryo-EM images, suggesting that the established image processing method is useful for producing dental restorative materials containing nano-fillers and for predicting homogenized mechanical properties. The homogenized mechanical properties indicated that the mechanical properties of the CAD/CAM RCB assumed perfect silane coupling between the fillers and resin matrix.
Publisher
Elsevier Ltd
Source Title
Journal of Prosthodontic Research
Volume (Issue)
63(1)
Page
90-94
Date of Issued
2019-01-01
Language
English
Handle URL
https://hdl.handle.net/11094/93095
PISSN
18831958
Relation.isIdenticalTo
DOI (Publisher Version)
https://doi.org/10.1016/j.jpor.2018.09.001
Access Rights
open access
CopyRight
© 2019 Japan Prosthodontic Society
oaire:version
Version of Record
Category
学術雑誌論文 Journal Article