Treatment and follow-up of late onset intra hepatic bile duct stones in congenital biliary dilatation

Ueno, Takehisa; Deguchi, Koichi; Masahata, Kazunori; Nomura, Motonari; Watanabe, Miho; Kamiyama, Masafumi; Tazuke, Yuko; Yoshioka, Teppei; Nose, Satoko; Okuyama, Hiroomi

doi:https://doi.org/10.1007/s00383-022-05321-w

Treatment and follow-up of late onset intra hepatic bile duct stones in congenital biliary dilatation

Ueno, Takehisa; Deguchi, Koichi; Masahata, Kazunori et al.

Pediatric Surgery International, 2022, 39, 20

Number of Access:1,077（2025-07-22 21:56 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/96431

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Title	Treatment and follow-up of late onset intra hepatic bile duct stones in congenital biliary dilatation
Creator	NRID 1000010456957 1000010456957 ORCID 0000-0002-4639-8814 0000-0002-4639-8814 researchmap permalink ueno-pedsurg ueno-pedsurg Scopus Author ID 21743992300 21743992300 CreatorName Ueno, Takehisa
	NRID 1000000747082 1000000747082 researchmap permalink deguchi_koichi deguchi_koichi Scopus Author ID 57139781700 57139781700 CreatorName Deguchi, Koichi
	NRID 1000040588381 1000040588381 CreatorName Masahata, Kazunori
	NRID 1000040546909 1000040546909 researchmap permalink moto_pedsurg moto_pedsurg Scopus Author ID 35208741700 35208741700 ORCID 0009-0004-0959-7461 0009-0004-0959-7461 CreatorName Nomura, Motonari
	NRID 1000040791728 1000040791728 researchmap permalink miho miho Scopus Author ID 56282966800 56282966800 ORCID 0000-0001-6691-0611 0000-0001-6691-0611 CreatorName Watanabe, Miho
	NRID 1000020403074 1000020403074 researchmap permalink kamiyamapedsurg kamiyamapedsurg Scopus Author ID 55559187300 55559187300 CreatorName Kamiyama, Masafumi
	NRID 1000010397698 1000010397698 researchmap permalink yukotazuke-osaka yukotazuke-osaka Scopus Author ID 7006109798 7006109798 ORCID 0000-0002-8335-0414 0000-0002-8335-0414 CreatorName Tazuke, Yuko
	NRID 1000060814605 1000060814605 researchmap permalink teyoshioka teyoshioka Scopus Author ID 56562390600 56562390600 CreatorName Yoshioka, Teppei
	NRID 1000090467564 1000090467564 CreatorName Nose, Satoko
	NRID 1000030252670 1000030252670 researchmap permalink okuyamahiroomi okuyamahiroomi Scopus Author ID 35496082300 35496082300 ORCID 0000-0002-1347-282X 0000-0002-1347-282X CreatorName Okuyama, Hiroomi
Subject	Congenital biliary dilatation
	Double-balloon enteroscopy
	Intrahepatic bile duct
	Percutaneous transhepatic cholangiodrainage
Description	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00383-022-05321-w.
Abstract	Purpose: The postoperative course after surgery for congenital biliary dilatation (CBD) has some complications. Intrahepatic bile duct (IHBD) stones were known as a late complication. We report on the treatment and long-term follow-up of postoperative IHBD stones in our department. Methods: Patients who underwent CBD surgery at age 15 years or younger in our department were identified. Those followed up for 5 years or more were enrolled. Annual blood chemistry tests and abdominal ultrasonography were performed. Each patient’s surgical procedure, IHBD stone diagnosis, treatments, and outcomes were retrospectively assessed. Results: Fifty-one patients were analyzed. The median age at the last visit was 24 years (range 7–45 years), and the median age at CBD surgery was 3 years. Eight patients (16%) developed late-onset IHBD stones. The median age at onset was 25 years, and the median duration after surgery was 20 years. The initial treatment was double-balloon enteroscopy (DBE) in 4 cases, which resulted in stone removal in 3 of the 4 patients (75%). Conclusion: Since CBD may cause late-onset IHBD stones, continuous follow-up is required even in adulthood. In this study, DBE was effective and minimally invasive, and it is recommended as the initial treatment.
Publisher	Springer Science and Business Media Deutschland GmbH
Source Title	Pediatric Surgery International
Volume (Issue)	39
Page	20
Date of Issued	2022-11-30
Language	English
Handle URL	https://hdl.handle.net/11094/96431
PISSN	01790358
eISSN	14379813
Relation.isVersionOf	DOI (Publisher Version) https://doi.org/10.1007/s00383-022-05321-w
Access Rights	open access
CopyRight	© 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
oaire:version	Accepted Manuscript
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCTERMS.bibliographicCitation	Pediatric Surgery International. 2022, 39, p. 20
DC.title	Treatment and follow-up of late onset intra hepatic bile duct stones in congenital biliary dilatation
DC.creator	Ueno, Takehisa
	Deguchi, Koichi
	Masahata, Kazunori
	Nomura, Motonari
	Watanabe, Miho
	Kamiyama, Masafumi
	Tazuke, Yuko
	Yoshioka, Teppei
	Nose, Satoko
	Okuyama, Hiroomi
DC.publisher	Springer Science and Business Media Deutschland GmbH
DC.language' scheme='DCTERMS.RFC1766	English
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2022-11-30
DC.identifier	https://doi.org/10.1007/s00383-022-05321-w
DC.subject	Congenital biliary dilatation
	Double-balloon enteroscopy
	Intrahepatic bile duct
	Percutaneous transhepatic cholangiodrainage
DC.description	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00383-022-05321-w.
DCTERMS.abstract	Purpose: The postoperative course after surgery for congenital biliary dilatation (CBD) has some complications. Intrahepatic bile duct (IHBD) stones were known as a late complication. We report on the treatment and long-term follow-up of postoperative IHBD stones in our department. Methods: Patients who underwent CBD surgery at age 15 years or younger in our department were identified. Those followed up for 5 years or more were enrolled. Annual blood chemistry tests and abdominal ultrasonography were performed. Each patient’s surgical procedure, IHBD stone diagnosis, treatments, and outcomes were retrospectively assessed. Results: Fifty-one patients were analyzed. The median age at the last visit was 24 years (range 7–45 years), and the median age at CBD surgery was 3 years. Eight patients (16%) developed late-onset IHBD stones. The median age at onset was 25 years, and the median duration after surgery was 20 years. The initial treatment was double-balloon enteroscopy (DBE) in 4 cases, which resulted in stone removal in 3 of the 4 patients (75%). Conclusion: Since CBD may cause late-onset IHBD stones, continuous follow-up is required even in adulthood. In this study, DBE was effective and minimally invasive, and it is recommended as the initial treatment.
DC.rights	© 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
DC.format	96431
citation_title	Treatment and follow-up of late onset intra hepatic bile duct stones in congenital biliary dilatation
citation_author	Ueno, Takehisa
	Deguchi, Koichi
	Masahata, Kazunori
	Nomura, Motonari
	Watanabe, Miho
	Kamiyama, Masafumi
	Tazuke, Yuko
	Yoshioka, Teppei
	Nose, Satoko
	Okuyama, Hiroomi
citation_publisher	Springer Science and Business Media Deutschland GmbH
citation_language	English
citation_date	2022-11-30
citation_journal_title	Pediatric Surgery International
citation_volume	39
citation_firstpage	20
citation_doi	https://doi.org/10.1007/s00383-022-05321-w
citation_public_url	https://hdl.handle.net/11094/96431

Treatment and follow-up of late onset intra hepatic bile duct stones in congenital biliary dilatation

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