Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans

Iwata, Takamitsu; Yanagisawa, Takufumi; Ikegaya, Yuji; Smallwood, Jonathan; Fukuma, Ryohei; Oshino, Satoru; Tani, Naoki; Khoo, Hui Ming; Kishima, Haruhiko

doi:https://doi.org/10.1038/s41467-024-48367-1

Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans

Iwata, Takamitsu; Yanagisawa, Takufumi; Ikegaya, Yuji et al.

Nature Communications, 2024, 15(1), 4078

Number of Access:1,446（2025-08-13 22:16 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/97800

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Title	Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans
Creator	researchmap permalink takamitsuiwata takamitsuiwata ORCID 0000-0003-2533-0551 0000-0003-2533-0551 CreatorName Iwata, Takamitsu
	NRID 1000090533802 1000090533802 ORCID 0000-0002-2057-0612 0000-0002-2057-0612 researchmap permalink takufumi takufumi Scopus Author ID 16553812400 16553812400 CreatorName Yanagisawa, Takufumi
	NRID 1000010302613 1000010302613 CreatorName Ikegaya, Yuji
	CreatorName Smallwood, Jonathan
	NRID 1000020564884 1000020564884 researchmap permalink fukuma fukuma Scopus Author ID 47960972500 47960972500 CreatorName Fukuma, Ryohei
	NRID 1000040403050 1000040403050 ORCID 0000-0002-4248-2322 0000-0002-4248-2322 researchmap permalink handai_ns_oshino handai_ns_oshino Scopus Author ID 6602717325 6602717325 CreatorName Oshino, Satoru
	NRID 1000020598370 1000020598370 researchmap permalink n_taniOsakaUniv n_taniOsakaUniv Scopus Author ID 7103335692 7103335692 CreatorName Tani, Naoki
	NRID 1000070591022 1000070591022 ORCID 0000-0002-4039-0520 0000-0002-4039-0520 researchmap permalink hmkhoo hmkhoo Scopus Author ID 55314143200 55314143200 CreatorName Khoo, Hui Ming
	NRID 1000010332743 1000010332743 researchmap permalink hkishima hkishima Scopus Author ID 6603783358 6603783358 ORCID 0000-0002-9041-2337 0000-0002-9041-2337 CreatorName Kishima, Haruhiko
Description	Iwata T., Yanagisawa T., Ikegaya Y., et al. Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans. Nature Communications 15, 4078 (2024); https://doi.org/https://doi.org/10.1038/s41467-024-48367-1.
Abstract	Core features of human cognition highlight the importance of the capacity to focus on information distinct from events in the here and now, such as mind wandering. However, the brain mechanisms that underpin these self-generated states remain unclear. An emerging hypothesis is that self-generated states depend on the process of memory replay, which is linked to sharp-wave ripples (SWRs), which are transient high-frequency oscillations originating in the hippocampus. Local field potentials were recorded from the hippocampus of 10 patients with epilepsy for up to 15 days, and experience sampling was used to describe their association with ongoing thought patterns. The SWR rates were higher during extended periods of time when participants’ ongoing thoughts were more vivid, less desirable, had more imaginable properties, and exhibited fewer correlations with an external task. These data suggest a role for SWR in the patterns of ongoing thoughts that humans experience in daily life.
Publisher	Nature Research
Source Title	Nature Communications
Volume (Issue)	15(1)
Page	4078
Date of Issued	2024-05-22
Language	English
Handle URL	https://hdl.handle.net/11094/97800
eISSN	20411723
Relation.isIdenticalTo	DOI (Publisher Version) https://doi.org/10.1038/s41467-024-48367-1
Access Rights	open access
CopyRight	This article is licensed under a Creative Commons Attribution 4.0 International License.
oaire:version	Version of Record
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCTERMS.bibliographicCitation	Nature Communications. 2024, 15(1), p. 4078
DC.title	Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans
DC.creator	Iwata, Takamitsu
	Yanagisawa, Takufumi
	Ikegaya, Yuji
	Smallwood, Jonathan
	Fukuma, Ryohei
	Oshino, Satoru
	Tani, Naoki
	Khoo, Hui Ming
	Kishima, Haruhiko
DC.publisher	Nature Research
DC.language' scheme='DCTERMS.RFC1766	English
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2024-05-22
DC.identifier	https://doi.org/10.1038/s41467-024-48367-1
DC.description	Iwata T., Yanagisawa T., Ikegaya Y., et al. Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans. Nature Communications 15, 4078 (2024); https://doi.org/https://doi.org/10.1038/s41467-024-48367-1.
DCTERMS.abstract	Core features of human cognition highlight the importance of the capacity to focus on information distinct from events in the here and now, such as mind wandering. However, the brain mechanisms that underpin these self-generated states remain unclear. An emerging hypothesis is that self-generated states depend on the process of memory replay, which is linked to sharp-wave ripples (SWRs), which are transient high-frequency oscillations originating in the hippocampus. Local field potentials were recorded from the hippocampus of 10 patients with epilepsy for up to 15 days, and experience sampling was used to describe their association with ongoing thought patterns. The SWR rates were higher during extended periods of time when participants’ ongoing thoughts were more vivid, less desirable, had more imaginable properties, and exhibited fewer correlations with an external task. These data suggest a role for SWR in the patterns of ongoing thoughts that humans experience in daily life.
DC.rights	This article is licensed under a Creative Commons Attribution 4.0 International License.
DC.format	97800
citation_title	Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans
citation_author	Iwata, Takamitsu
	Yanagisawa, Takufumi
	Ikegaya, Yuji
	Smallwood, Jonathan
	Fukuma, Ryohei
	Oshino, Satoru
	Tani, Naoki
	Khoo, Hui Ming
	Kishima, Haruhiko
citation_publisher	Nature Research
citation_language	English
citation_date	2024-05-22
citation_journal_title	Nature Communications
citation_volume	15
citation_issue	1
citation_firstpage	4078
citation_doi	https://doi.org/10.1038/s41467-024-48367-1
citation_public_url	https://hdl.handle.net/11094/97800

Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans

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