Long-term outcomes of transapical-transcatheter aortic valve replacement

Maeda, Koichi; Shimamura, Kazuo; Mizote, Isamu; Nakamura, Daisuke; Yamashita, Kizuku; Kawamura, Ai; Yoshioka, Daisuke; Sakata, Yasushi; Miyagawa, Shigeru

doi:https://doi.org/10.1007/s11748-024-02095-x

Long-term outcomes of transapical-transcatheter aortic valve replacement

Maeda, Koichi; Shimamura, Kazuo; Mizote, Isamu et al.

General Thoracic and Cardiovascular Surgery, 2024

Number of Access:56（2025-04-30 13:14 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/98399

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Title	Long-term outcomes of transapical-transcatheter aortic valve replacement
Creator	NRID 1000050644994 1000050644994 researchmap permalink koichi-maeda koichi-maeda Scopus Author ID 55318832600 55318832600 CreatorName Maeda, Koichi
	NRID 1000010507205 1000010507205 researchmap permalink kazuo-shimamura kazuo-shimamura Scopus Author ID 35969640700 35969640700 CreatorName Shimamura, Kazuo
	NRID 1000010584609 1000010584609 researchmap permalink mizoteisamu mizoteisamu Scopus Author ID 8266113500 8266113500 CreatorName Mizote, Isamu
	NRID 1000030869970 1000030869970 researchmap permalink daifromn0525 daifromn0525 CreatorName Nakamura, Daisuke
	NRID 1000060778661 1000060778661 researchmap permalink ky_osaka-u_2020 ky_osaka-u_2020 Scopus Author ID 57188740592 57188740592 CreatorName Yamashita, Kizuku
	NRID 1000010838923 1000010838923 researchmap permalink a-kawamura a-kawamura Scopus Author ID 56414159900 56414159900 CreatorName Kawamura, Ai
	NRID 1000040645959 1000040645959 researchmap permalink d-yoshioka d-yoshioka Scopus Author ID 7003892845 7003892845 CreatorName Yoshioka, Daisuke
	NRID 1000000397671 1000000397671 ORCID 0000-0002-5618-4721 0000-0002-5618-4721 researchmap permalink C4589 C4589 Scopus Author ID 35395964700 35395964700 CreatorName Sakata, Yasushi
	NRID 1000070544237 1000070544237 ORCID 0000-0003-0015-6569 0000-0003-0015-6569 researchmap permalink s-miyagawa3154 s-miyagawa3154 Scopus Author ID 55560624700 55560624700 CreatorName Miyagawa, Shigeru
Subject	Alternative approach
	Aortic stenosis
	Transapical-transcatheter aortic valve replacement
Description	The version of record of this article, first published in General Thoracic and Cardiovascular Surgery, is available online at Publisher’s website: https://doi.org/10.1007/s11748-024-02095-x.
Abstract	Objective: Transapical-transcatheter aortic valve replacement is one of the main interventions indicated for patients where access via peripheral vessels is challenging. However, there have been no reports on the long-term outcomes of this intervention. Here, we report the long-term outcomes of this intervention. Methods: Among 178 patients who underwent transapical-transcatheter aortic valve replacement between October 2009 and July 2023, 173 patients who underwent this intervention for native aortic stenosis were included in this study, and early and long-term results were evaluated. Results: The mean age was 82.4 ± 6.4 years, 52.6% were women, mean body area was 1.46 ± 0.17 m2, and the Society of Thoracic Surgeons Predicted Risk of Mortality was 11.2 ± 9.9%. In-hospital mortality was observed in three patients (1.7%). Mean follow-up duration was 4.3 ± 2.8 years, and the survival rates at 1-, 3-, 5-, and 8-years were 84.9%, 67.1%, 47.0%, and 22.1%, respectively. Freedom from cardiovascular mortality at 1, 3, 5, and 8-years was 92.9%, 86.1%, 75.8%, and 53.5%, respectively. The freedom from disabling stroke rates at 1, 3, 5, and 8-years were 95.0%, 92.4%, 92.4%, and 90.8%, respectively. Multivariate analysis revealed that male (Hazard Ratio 1.85, 95%Confidence Interval 1.27−2.70, p = 0.0012) and hemodialysis (Hazard Ratio 1.64, 95%Confidence Interval 1.00−2.67, p = 0.049) were significant poor prognosis factors. Conclusions: Long-term outcomes of transapical-transcatheter aortic valve replacement were satisfactory. Despite the variety of available approaches, the role of transapical-transcatheter aortic valve replacement, which has low vascular impact, has not been completely lost.
Publisher	Springer
Source Title	General Thoracic and Cardiovascular Surgery
Date of Issued	2024-10-23
Language	English
Handle URL	https://hdl.handle.net/11094/98399
PISSN	18636705
eISSN	18636713
Relation.isIdenticalTo	DOI (Publisher Version) https://doi.org/10.1007/s11748-024-02095-x
Access Rights	open access
CopyRight	This article is licensed under a Creative Commons Attribution 4.0 International License.
oaire:version	Version of Record
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCTERMS.bibliographicCitation	General Thoracic and Cardiovascular Surgery. 2024
DC.title	Long-term outcomes of transapical-transcatheter aortic valve replacement
DC.creator	Maeda, Koichi
	Shimamura, Kazuo
	Mizote, Isamu
	Nakamura, Daisuke
	Yamashita, Kizuku
	Kawamura, Ai
	Yoshioka, Daisuke
	Sakata, Yasushi
	Miyagawa, Shigeru
DC.publisher	Springer
DC.language' scheme='DCTERMS.RFC1766	English
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2024-10-23
DC.identifier	https://doi.org/10.1007/s11748-024-02095-x
DC.subject	Alternative approach
	Aortic stenosis
	Transapical-transcatheter aortic valve replacement
DC.description	The version of record of this article, first published in General Thoracic and Cardiovascular Surgery, is available online at Publisher’s website: https://doi.org/10.1007/s11748-024-02095-x.
DCTERMS.abstract	Objective: Transapical-transcatheter aortic valve replacement is one of the main interventions indicated for patients where access via peripheral vessels is challenging. However, there have been no reports on the long-term outcomes of this intervention. Here, we report the long-term outcomes of this intervention. Methods: Among 178 patients who underwent transapical-transcatheter aortic valve replacement between October 2009 and July 2023, 173 patients who underwent this intervention for native aortic stenosis were included in this study, and early and long-term results were evaluated. Results: The mean age was 82.4 ± 6.4 years, 52.6% were women, mean body area was 1.46 ± 0.17 m2, and the Society of Thoracic Surgeons Predicted Risk of Mortality was 11.2 ± 9.9%. In-hospital mortality was observed in three patients (1.7%). Mean follow-up duration was 4.3 ± 2.8 years, and the survival rates at 1-, 3-, 5-, and 8-years were 84.9%, 67.1%, 47.0%, and 22.1%, respectively. Freedom from cardiovascular mortality at 1, 3, 5, and 8-years was 92.9%, 86.1%, 75.8%, and 53.5%, respectively. The freedom from disabling stroke rates at 1, 3, 5, and 8-years were 95.0%, 92.4%, 92.4%, and 90.8%, respectively. Multivariate analysis revealed that male (Hazard Ratio 1.85, 95%Confidence Interval 1.27−2.70, p = 0.0012) and hemodialysis (Hazard Ratio 1.64, 95%Confidence Interval 1.00−2.67, p = 0.049) were significant poor prognosis factors. Conclusions: Long-term outcomes of transapical-transcatheter aortic valve replacement were satisfactory. Despite the variety of available approaches, the role of transapical-transcatheter aortic valve replacement, which has low vascular impact, has not been completely lost.
DC.rights	This article is licensed under a Creative Commons Attribution 4.0 International License.
DC.format	98399
citation_title	Long-term outcomes of transapical-transcatheter aortic valve replacement
citation_author	Maeda, Koichi
	Shimamura, Kazuo
	Mizote, Isamu
	Nakamura, Daisuke
	Yamashita, Kizuku
	Kawamura, Ai
	Yoshioka, Daisuke
	Sakata, Yasushi
	Miyagawa, Shigeru
citation_publisher	Springer
citation_language	English
citation_date	2024-10-23
citation_journal_title	General Thoracic and Cardiovascular Surgery
citation_doi	https://doi.org/10.1007/s11748-024-02095-x
citation_public_url	https://hdl.handle.net/11094/98399

Long-term outcomes of transapical-transcatheter aortic valve replacement

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