Development of novel rectal/uterine clamping device

Urabe, Shoichiro; Hata, Taishi; Kobayashi, Eiji; Ishii, Yuji; Ushimaru, Yuki; Takeda, Mitsunobu; Sekido, Yuki; Hata, Tsuyoshi; Hamabe, Atsushi; Ogino, Takayuki; Miyoshi, Norikatsu; Uemura, Mamoru; Yamamoto, Hirofumi; Doki, Yuichiro; Eguchi, Hidetoshi; Nakajima, Kiyokazu

doi:https://doi.org/10.1038/s41598-024-75103-y

Development of novel rectal/uterine clamping device

Urabe, Shoichiro; Hata, Taishi; Kobayashi, Eiji et al.

Scientific Reports, 2024, 14, 22960

Number of Access:2,431（2025-08-15 06:45 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/98542

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Title	Development of novel rectal/uterine clamping device
Creator	CreatorName Urabe, Shoichiro
	NRID 1000070644912 1000070644912 researchmap permalink taishi_hata taishi_hata CreatorName Hata, Taishi
	NRID 1000050614773 1000050614773 researchmap permalink eiji-kobayashi eiji-kobayashi Scopus Author ID 50262045800 50262045800 CreatorName Kobayashi, Eiji
	CreatorName Ishii, Yuji
	CreatorName Ushimaru, Yuki
	NRID 1000090768962 1000090768962 researchmap permalink takeda27832 takeda27832 CreatorName Takeda, Mitsunobu
	NRID 1000000781709 1000000781709 researchmap permalink 00781709 00781709 Scopus Author ID 57193691322 57193691322 CreatorName Sekido, Yuki
	NRID 1000080749747 1000080749747 researchmap permalink tsuyoshi_hata tsuyoshi_hata Scopus Author ID 57189996374 57189996374 CreatorName Hata, Tsuyoshi
	NRID 1000060621034 1000060621034 ORCID 0000-0001-5535-3514 0000-0001-5535-3514 researchmap permalink hamabe_atsushi hamabe_atsushi CreatorName Hamabe, Atsushi
	NRID 1000050597458 1000050597458 researchmap permalink togino04 togino04 Scopus Author ID 57200254430 57200254430 CreatorName Ogino, Takayuki
	NRID 1000020528624 1000020528624 researchmap permalink nor nor Scopus Author ID 9242781300 9242781300 CreatorName Miyoshi, Norikatsu
	NRID 1000010528483 1000010528483 ORCID 0000-0001-6285-5619 0000-0001-6285-5619 researchmap permalink mamoruuemura mamoruuemura Scopus Author ID 36796497400 36796497400 CreatorName Uemura, Mamoru
	NRID 1000030322184 1000030322184 researchmap permalink kobunyam kobunyam Scopus Author ID 12805320700 12805320700 CreatorName Yamamoto, Hirofumi
	NRID 1000020291445 1000020291445 researchmap permalink ydoki3251 ydoki3251 Scopus Author ID 7006390687 7006390687 CreatorName Doki, Yuichiro
	NRID 1000090542118 1000090542118 researchmap permalink abcdabcdabcd abcdabcdabcd Scopus Author ID 7101627772 7101627772 CreatorName Eguchi, Hidetoshi
	NRID 1000030432537 1000030432537 researchmap permalink project_engine project_engine Scopus Author ID 7404396263 7404396263 ORCID 0000-0001-8635-7585 0000-0001-8635-7585 CreatorName Nakajima, Kiyokazu
Subject	Bursting pressure
	Clamper
	Clamping device
	Laparoscopic surgery
	micro-CT
Description	Urabe S., Hata T., Kobayashi E., et al. Development of novel rectal/uterine clamping device. Scientific Reports 14, 22960 (2024); https://doi.org/10.1038/s41598-024-75103-y.
Abstract	We developed a novel clamping device for laparoscopic surgery, free from conventional pinch structure, capable of uniformly occluding any ductal organ. This study aimed to evaluate performance of the new clamper compared to the pinch-type clamper. The new clamper consists of two metal bars with ties at each end, which enables parallel clamping. A resected porcine stomach was used, with an infusion tube at the anal end to increase intra-luminal pressure. The oral side of the stomach was clamped with either the new clamper or the pinch-type clamper, and their performances were evaluated in qualitative and semi-quantitative manner. Qualitative evaluation involved imaging the clamping site at intra-gastric pressures from 0 to 15 mmHg using microfocus computed tomography. The new clamper showed no gap even under increased intra-luminal pressure, while the pinch-type clamper showed a gap on the distal side. Quantitative evaluation measured bursting pressure under continuous air insufflation. Air leakages were observed in the new clamper at higher intra-luminal pressures than in the pinch-type clamper (46.1 mmHg vs. 13.6 mmHg, P < 0.01). Our new clamping device showed superior performance in preclinical setting compared to the conventional pinch-type clamper. We are currently working on its design freezing and aiming for early commercialization.
Publisher	Nature Research
Source Title	Scientific Reports
Volume (Issue)	14
Page	22960
Date of Issued	2024-10-03
Language	English
Handle URL	https://hdl.handle.net/11094/98542
eISSN	20452322
Relation.isIdenticalTo	DOI (Publisher Version) https://doi.org/10.1038/s41598-024-75103-y
Access Rights	open access
CopyRight	This article is licensed under a Creative Commons Attribution 4.0 International License.
oaire:version	Version of Record
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCTERMS.bibliographicCitation	Scientific Reports. 2024, 14, p. 22960
DC.title	Development of novel rectal/uterine clamping device
DC.creator	Urabe, Shoichiro
	Hata, Taishi
	Kobayashi, Eiji
	Ishii, Yuji
	Ushimaru, Yuki
	Takeda, Mitsunobu
	Sekido, Yuki
	Hata, Tsuyoshi
	Hamabe, Atsushi
	Ogino, Takayuki
	Miyoshi, Norikatsu
	Uemura, Mamoru
	Yamamoto, Hirofumi
	Doki, Yuichiro
	Eguchi, Hidetoshi
	Nakajima, Kiyokazu
DC.publisher	Nature Research
DC.language' scheme='DCTERMS.RFC1766	English
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2024-10-03
DC.identifier	https://doi.org/10.1038/s41598-024-75103-y
DC.subject	Bursting pressure
	Clamper
	Clamping device
	Laparoscopic surgery
	micro-CT
DC.description	Urabe S., Hata T., Kobayashi E., et al. Development of novel rectal/uterine clamping device. Scientific Reports 14, 22960 (2024); https://doi.org/10.1038/s41598-024-75103-y.
DCTERMS.abstract	We developed a novel clamping device for laparoscopic surgery, free from conventional pinch structure, capable of uniformly occluding any ductal organ. This study aimed to evaluate performance of the new clamper compared to the pinch-type clamper. The new clamper consists of two metal bars with ties at each end, which enables parallel clamping. A resected porcine stomach was used, with an infusion tube at the anal end to increase intra-luminal pressure. The oral side of the stomach was clamped with either the new clamper or the pinch-type clamper, and their performances were evaluated in qualitative and semi-quantitative manner. Qualitative evaluation involved imaging the clamping site at intra-gastric pressures from 0 to 15 mmHg using microfocus computed tomography. The new clamper showed no gap even under increased intra-luminal pressure, while the pinch-type clamper showed a gap on the distal side. Quantitative evaluation measured bursting pressure under continuous air insufflation. Air leakages were observed in the new clamper at higher intra-luminal pressures than in the pinch-type clamper (46.1 mmHg vs. 13.6 mmHg, P < 0.01). Our new clamping device showed superior performance in preclinical setting compared to the conventional pinch-type clamper. We are currently working on its design freezing and aiming for early commercialization.
DC.rights	This article is licensed under a Creative Commons Attribution 4.0 International License.
DC.format	98542
citation_title	Development of novel rectal/uterine clamping device
citation_author	Urabe, Shoichiro
	Hata, Taishi
	Kobayashi, Eiji
	Ishii, Yuji
	Ushimaru, Yuki
	Takeda, Mitsunobu
	Sekido, Yuki
	Hata, Tsuyoshi
	Hamabe, Atsushi
	Ogino, Takayuki
	Miyoshi, Norikatsu
	Uemura, Mamoru
	Yamamoto, Hirofumi
	Doki, Yuichiro
	Eguchi, Hidetoshi
	Nakajima, Kiyokazu
citation_publisher	Nature Research
citation_language	English
citation_date	2024-10-03
citation_journal_title	Scientific Reports
citation_volume	14
citation_firstpage	22960
citation_doi	https://doi.org/10.1038/s41598-024-75103-y
citation_public_url	https://hdl.handle.net/11094/98542

Development of novel rectal/uterine clamping device

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