Assessing the Risk of Postoperative Delirium Through Comprehensive Geriatric Assessment and Eastern Cooperative Oncology Group Performance Status of Elderly Patients With Gastric Cancer

Itami, Takefumi; Yamamoto, Kazuyoshi; Kurokawa, Yukinori; Saito, Takuro; Takahashi, Tsuyoshi; Momose, Kota; Yamashita, Kotaro; Tanaka, Koji; Makino, Tomoki; Yasunobe, Yukiko; Akasaka, Hiroshi; Fujimoto, Taku; Yamamoto, Koichi; Nakajima, Kiyokazu; Eguchi, Hidetoshi; Doki, Yuichiro

doi:https://doi.org/10.1245/s10434-024-16034-w

Assessing the Risk of Postoperative Delirium Through Comprehensive Geriatric Assessment and Eastern Cooperative Oncology Group Performance Status of Elderly Patients With Gastric Cancer

Itami, Takefumi; Yamamoto, Kazuyoshi; Kurokawa, Yukinori et al.

Annals of Surgical Oncology, 2024, 31, 9039-9047

Number of Access:2,495（2025-07-18 17:14 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/98911

Link to primary information

File	Format	Terms of use	Size	Views	Date.Available	Description	information
AnnSurgOncol_31_9039	pdf	None	1.15 MB	18	2025.01.06

Creative Commons : Attribution

Item Information

Output File Export EndNote Basic Export Mendeley

Title	Assessing the Risk of Postoperative Delirium Through Comprehensive Geriatric Assessment and Eastern Cooperative Oncology Group Performance Status of Elderly Patients With Gastric Cancer
Creator	CreatorName Itami, Takefumi
	NRID 1000070528637 1000070528637 researchmap permalink kymamoto13 kymamoto13 Scopus Author ID 12764120500 12764120500 CreatorName Yamamoto, Kazuyoshi
	NRID 1000010470197 1000010470197 researchmap permalink krkw krkw Scopus Author ID 7202562410 7202562410 CreatorName Kurokawa, Yukinori
	NRID 1000020646468 1000020646468 researchmap permalink tsaito19 tsaito19 Scopus Author ID 57211629912 57211629912 CreatorName Saito, Takuro
	NRID 1000050452389 1000050452389 ORCID 0000-0003-2397-1478 0000-0003-2397-1478 researchmap permalink mihogaoka13611 mihogaoka13611 Scopus Author ID 56182761100 56182761100 CreatorName Takahashi, Tsuyoshi
	NRID 1000050749752 1000050749752 researchmap permalink kom2005 kom2005 CreatorName Momose, Kota
	NRID 1000020747159 1000020747159 researchmap permalink k-yamashita k-yamashita Scopus Author ID 57191498316 57191498316 CreatorName Yamashita, Kotaro
	NRID 1000070621019 1000070621019 ORCID 0000-0001-5178-9388 0000-0001-5178-9388 researchmap permalink koji_tanaka koji_tanaka Scopus Author ID 55628548952 55628548952 CreatorName Tanaka, Koji
	NRID 1000080528620 1000080528620 researchmap permalink _-_-_- _-_-_- Scopus Author ID 56339970700 56339970700 CreatorName Makino, Tomoki
	CreatorName Yasunobe, Yukiko
	NRID 1000070468081 1000070468081 researchmap permalink hiroshi-akasaka hiroshi-akasaka Scopus Author ID 35445539600 35445539600 CreatorName Akasaka, Hiroshi
	NRID 1000010854284 1000010854284 researchmap permalink tfujimoto0319 tfujimoto0319 CreatorName Fujimoto, Taku
	NRID 1000000528424 1000000528424 ORCID 0000-0003-0107-9315 0000-0003-0107-9315 researchmap permalink kymt0410 kymt0410 Scopus Author ID 55624482466 55624482466 CreatorName Yamamoto, Koichi
	NRID 1000030432537 1000030432537 ORCID 0000-0001-8635-7585 0000-0001-8635-7585 researchmap permalink project_engine project_engine Scopus Author ID 7404396263 7404396263 CreatorName Nakajima, Kiyokazu
	NRID 1000090542118 1000090542118 researchmap permalink abcdabcdabcd abcdabcdabcd Scopus Author ID 7101627772 7101627772 CreatorName Eguchi, Hidetoshi
	NRID 1000020291445 1000020291445 researchmap permalink ydoki3251 ydoki3251 Scopus Author ID 7006390687 7006390687 CreatorName Doki, Yuichiro
Subject	Comprehensive geriatric assessment
	Delirium
	Eastern Cooperative Oncology Group performance status
	Elderly patients
	Gastrectomy
	Gastric cancer
	Mini-Mental State Examination
Description	The version of record of this article, first published in Annals of Surgical Oncology, is available online at Publisher’s website: https://doi.org/10.1245/s10434-024-16034-w.
Abstract	Background: Postoperative delirium is especially common and often problematic among elderly patients undergoing surgery. This study aimed to explore factors that can predict postoperative delirium in elderly patients undergoing gastric cancer surgery. Methods: This cohort study included 255 patients age 75 years or older who underwent gastric cancer surgery between July 2010 and December 2020. All the patients underwent preoperative comprehensive geriatric assessment (CGA) evaluation by a geriatrician. In addition to the CGA items, this study investigated the association between postoperative delirium and clinicopathologic factors, including Eastern Cooperative Oncology Group performance status (ECOG-PS). Results: The most common postoperative complication was delirium, present in 31 patients (12.2%). The group with delirium was significantly more likely to have ECOG-PS ≥ 2, diabetes mellitus, cardiovascular disease, or cerebral infarction. The CGA showed frailty in the Instrumental Activities of Daily Living scale (IADL), the Mini-Mental State Examination (MMSE), the Vitality Index (VI), and the Geriatric Depression Scale 15 (GDS-15). In the multivariate analysis, the independent risk factors for delirium were ECOG-PS ≥ 2 (P = 0.002) and MMSE-frailty (P < 0.001). Using an MMSE score of ≤ 23 and an ECOG-PS score of ≥ 2 as cutoffs, postoperative delirium was predicted with a sensitivity of 80.7% and a specificity of 74.1%. Conclusion: Postoperative delirium might be more easily predicted based on the combination of MMSE and ECOG-PS for elderly patients with gastric cancer undergoing gastrectomy.
Publisher	Springer Science and Business Media Deutschland GmbH
Source Title	Annals of Surgical Oncology
Volume (Issue)	31
Page	9039-9047
Date of Issued	2024-12-01
Language	English
Handle URL	https://hdl.handle.net/11094/98911
PISSN	10689265
eISSN	15344681
Relation.isIdenticalTo	DOI (Publisher Version) https://doi.org/10.1245/s10434-024-16034-w
Access Rights	open access
CopyRight	This article is licensed under a Creative Commons Attribution 4.0 International License.
oaire:version	Version of Record
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCTERMS.bibliographicCitation	Annals of Surgical Oncology. 2024, 31, p. 9039-9047
DC.title	Assessing the Risk of Postoperative Delirium Through Comprehensive Geriatric Assessment and Eastern Cooperative Oncology Group Performance Status of Elderly Patients With Gastric Cancer
DC.creator	Itami, Takefumi
	Yamamoto, Kazuyoshi
	Kurokawa, Yukinori
	Saito, Takuro
	Takahashi, Tsuyoshi
	Momose, Kota
	Yamashita, Kotaro
	Tanaka, Koji
	Makino, Tomoki
	Yasunobe, Yukiko
	Akasaka, Hiroshi
	Fujimoto, Taku
	Yamamoto, Koichi
	Nakajima, Kiyokazu
	Eguchi, Hidetoshi
	Doki, Yuichiro
DC.publisher	Springer Science and Business Media Deutschland GmbH
DC.language' scheme='DCTERMS.RFC1766	English
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2024-12-01
DC.identifier	https://doi.org/10.1245/s10434-024-16034-w
DC.subject	Comprehensive geriatric assessment
	Delirium
	Eastern Cooperative Oncology Group performance status
	Elderly patients
	Gastrectomy
	Gastric cancer
	Mini-Mental State Examination
DC.description	The version of record of this article, first published in Annals of Surgical Oncology, is available online at Publisher’s website: https://doi.org/10.1245/s10434-024-16034-w.
DCTERMS.abstract	Background: Postoperative delirium is especially common and often problematic among elderly patients undergoing surgery. This study aimed to explore factors that can predict postoperative delirium in elderly patients undergoing gastric cancer surgery. Methods: This cohort study included 255 patients age 75 years or older who underwent gastric cancer surgery between July 2010 and December 2020. All the patients underwent preoperative comprehensive geriatric assessment (CGA) evaluation by a geriatrician. In addition to the CGA items, this study investigated the association between postoperative delirium and clinicopathologic factors, including Eastern Cooperative Oncology Group performance status (ECOG-PS). Results: The most common postoperative complication was delirium, present in 31 patients (12.2%). The group with delirium was significantly more likely to have ECOG-PS ≥ 2, diabetes mellitus, cardiovascular disease, or cerebral infarction. The CGA showed frailty in the Instrumental Activities of Daily Living scale (IADL), the Mini-Mental State Examination (MMSE), the Vitality Index (VI), and the Geriatric Depression Scale 15 (GDS-15). In the multivariate analysis, the independent risk factors for delirium were ECOG-PS ≥ 2 (P = 0.002) and MMSE-frailty (P < 0.001). Using an MMSE score of ≤ 23 and an ECOG-PS score of ≥ 2 as cutoffs, postoperative delirium was predicted with a sensitivity of 80.7% and a specificity of 74.1%. Conclusion: Postoperative delirium might be more easily predicted based on the combination of MMSE and ECOG-PS for elderly patients with gastric cancer undergoing gastrectomy.
DC.rights	This article is licensed under a Creative Commons Attribution 4.0 International License.
DC.format	98911
citation_title	Assessing the Risk of Postoperative Delirium Through Comprehensive Geriatric Assessment and Eastern Cooperative Oncology Group Performance Status of Elderly Patients With Gastric Cancer
citation_author	Itami, Takefumi
	Yamamoto, Kazuyoshi
	Kurokawa, Yukinori
	Saito, Takuro
	Takahashi, Tsuyoshi
	Momose, Kota
	Yamashita, Kotaro
	Tanaka, Koji
	Makino, Tomoki
	Yasunobe, Yukiko
	Akasaka, Hiroshi
	Fujimoto, Taku
	Yamamoto, Koichi
	Nakajima, Kiyokazu
	Eguchi, Hidetoshi
	Doki, Yuichiro
citation_publisher	Springer Science and Business Media Deutschland GmbH
citation_language	English
citation_date	2024-12-01
citation_journal_title	Annals of Surgical Oncology
citation_volume	31
citation_firstpage	9039
citation_lastpage	9047
citation_doi	https://doi.org/10.1245/s10434-024-16034-w
citation_public_url	https://hdl.handle.net/11094/98911

Assessing the Risk of Postoperative Delirium Through Comprehensive Geriatric Assessment and Eastern Cooperative Oncology Group Performance Status of Elderly Patients With Gastric Cancer

Link to primary information

Item Information

Show details