Liver Failure From Ultra-Short Bowel Syndrome on the Intestinal Transplant Waiting List: A Retrospective Study

Noguchi, Y.; Ueno, T.; Matsuura, R.; Kodama, T.; Deguchi, K.; Umeda, S.; Yamamichi, T.; Nakahata, K.; Zenitani, M.; Takama, Y.; Yamanaka, H.; Tazuke, Y.; Okuyama, H.

doi:https://doi.org/10.1016/j.transproceed.2016.10.019

Liver Failure From Ultra-Short Bowel Syndrome on the Intestinal Transplant Waiting List: A Retrospective Study

Noguchi, Y.; Ueno, T.; Matsuura, R. et al.

Transplantation Proceedings, 2017, 49(1), 135-138

Number of Access:1,476（2025-07-22 21:55 Counts）

Identifier to cite or link to this item: https://hdl.handle.net/11094/99833

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Title	Liver Failure From Ultra-Short Bowel Syndrome on the Intestinal Transplant Waiting List: A Retrospective Study
Creator	CreatorName Noguchi, Y.
	NRID 1000010456957 1000010456957 ORCID 0000-0002-4639-8814 0000-0002-4639-8814 researchmap permalink ueno-pedsurg ueno-pedsurg Scopus Author ID 21743992300 21743992300 CreatorName Ueno, T.
	NRID 1000000747412 1000000747412 CreatorName Matsuura, R.
	NRID 1000060771045 1000060771045 CreatorName Kodama, T.
	NRID 1000000747082 1000000747082 researchmap permalink deguchi_koichi deguchi_koichi Scopus Author ID 57139781700 57139781700 CreatorName Deguchi, K.
	NRID 1000060715176 1000060715176 CreatorName Umeda, S.
	NRID 1000030715165 1000030715165 CreatorName Yamamichi, T.
	NRID 1000050643532 1000050643532 researchmap permalink nakahatakengo nakahatakengo CreatorName Nakahata, K.
	NRID 1000040643531 1000040643531 CreatorName Zenitani, M.
	NRID 1000050467560 1000050467560 researchmap permalink tytyty_ytytyt tytyty_ytytyt CreatorName Takama, Y.
	NRID 1000070467570 1000070467570 CreatorName Yamanaka, H.
	NRID 1000010397698 1000010397698 researchmap permalink yukotazuke-osaka yukotazuke-osaka Scopus Author ID 7006109798 7006109798 ORCID 0000-0002-8335-0414 0000-0002-8335-0414 CreatorName Tazuke, Y.
	NRID 1000030252670 1000030252670 researchmap permalink okuyamahiroomi okuyamahiroomi Scopus Author ID 35496082300 35496082300 ORCID 0000-0002-1347-282X 0000-0002-1347-282X CreatorName Okuyama, H.
Description	Noguchi Y., Ueno T., Matsuura R., et al. Liver Failure From Ultra-Short Bowel Syndrome on the Intestinal Transplant Waiting List: A Retrospective Study. Transplantation Proceedings 49, 135 (2017); https://doi.org/10.1016/j.transproceed.2016.10.019.
Abstract	Background: Patients with intestinal failure (IF) are candidates for intestinal transplantation (ITx). In Japan, these patients have few opportunities to undergo cadaveric ITx because of low rates of organ donation. The donor criteria and recipient priority for ITx are still unknown. We reviewed our cases of IF to investigate which patients should be prioritized for ITx. Methods: Patients with IF who were registered as candidates for cadaveric ITx between January 2010 and November 2015 in our institute were included in this retrospective study. Their data were gathered from their charts and analyzed. Results: Five patients were included. Their primary diseases included total colon aganglionosis (n = 1), chronic idiopathic intestinal pseudo-obstruction syndrome (n = 2), superior mesenteric vein embolization (n = 1), and graft loss after ITx (n = 1). Two patients died of liver failure (LF) during the waiting period. The remaining three are now alive and waiting for transplantation. The lengths of the remaining intestine were more than 20 cm in living cases but less than 20 cm in fatal cases. In the fatal cases, they had several episodes of catheter-related blood stream infection, which caused LF and acute renal failure. Conclusions: We identified two patients with less than 20 cm residual small bowel who died after acute deterioration of liver function. Patients with ultra-short bowel could have a higher risk of LF. Therefore, they should be referred as soon as possible to a specialized hospital where ITx is a choice of treatment for IF.
Publisher	Elsevier Inc.
Source Title	Transplantation Proceedings
Volume (Issue)	49(1)
Page	135-138
Date of Issued	2017-01-01
Language	English
Handle URL	https://hdl.handle.net/11094/99833
PISSN	00411345
eISSN	18732623
Relation.isVersionOf	DOI (Publisher Version) https://doi.org/10.1016/j.transproceed.2016.10.019
Access Rights	open access
CopyRight	© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
oaire:version	Accepted Manuscript
Category	学術雑誌論文 Journal Article

Resource Type	journal article
Local Type	Journal Article
DCTERMS.bibliographicCitation	Transplantation Proceedings. 2017, 49(1), p. 135-138
DC.title	Liver Failure From Ultra-Short Bowel Syndrome on the Intestinal Transplant Waiting List: A Retrospective Study
DC.creator	Noguchi, Y.
	Ueno, T.
	Matsuura, R.
	Kodama, T.
	Deguchi, K.
	Umeda, S.
	Yamamichi, T.
	Nakahata, K.
	Zenitani, M.
	Takama, Y.
	Yamanaka, H.
	Tazuke, Y.
	Okuyama, H.
DC.publisher	Elsevier Inc.
DC.language' scheme='DCTERMS.RFC1766	English
DCTERMS.issued' scheme='DCTERMS.W3CDTF	2017-01-01
DC.identifier	https://doi.org/10.1016/j.transproceed.2016.10.019
DC.description	Noguchi Y., Ueno T., Matsuura R., et al. Liver Failure From Ultra-Short Bowel Syndrome on the Intestinal Transplant Waiting List: A Retrospective Study. Transplantation Proceedings 49, 135 (2017); https://doi.org/10.1016/j.transproceed.2016.10.019.
DCTERMS.abstract	Background: Patients with intestinal failure (IF) are candidates for intestinal transplantation (ITx). In Japan, these patients have few opportunities to undergo cadaveric ITx because of low rates of organ donation. The donor criteria and recipient priority for ITx are still unknown. We reviewed our cases of IF to investigate which patients should be prioritized for ITx. Methods: Patients with IF who were registered as candidates for cadaveric ITx between January 2010 and November 2015 in our institute were included in this retrospective study. Their data were gathered from their charts and analyzed. Results: Five patients were included. Their primary diseases included total colon aganglionosis (n = 1), chronic idiopathic intestinal pseudo-obstruction syndrome (n = 2), superior mesenteric vein embolization (n = 1), and graft loss after ITx (n = 1). Two patients died of liver failure (LF) during the waiting period. The remaining three are now alive and waiting for transplantation. The lengths of the remaining intestine were more than 20 cm in living cases but less than 20 cm in fatal cases. In the fatal cases, they had several episodes of catheter-related blood stream infection, which caused LF and acute renal failure. Conclusions: We identified two patients with less than 20 cm residual small bowel who died after acute deterioration of liver function. Patients with ultra-short bowel could have a higher risk of LF. Therefore, they should be referred as soon as possible to a specialized hospital where ITx is a choice of treatment for IF.
DC.rights	© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
DC.format	99833
citation_title	Liver Failure From Ultra-Short Bowel Syndrome on the Intestinal Transplant Waiting List: A Retrospective Study
citation_author	Noguchi, Y.
	Ueno, T.
	Matsuura, R.
	Kodama, T.
	Deguchi, K.
	Umeda, S.
	Yamamichi, T.
	Nakahata, K.
	Zenitani, M.
	Takama, Y.
	Yamanaka, H.
	Tazuke, Y.
	Okuyama, H.
citation_publisher	Elsevier Inc.
citation_language	English
citation_date	2017-01-01
citation_journal_title	Transplantation Proceedings
citation_volume	49
citation_issue	1
citation_firstpage	135
citation_lastpage	138
citation_doi	https://doi.org/10.1016/j.transproceed.2016.10.019
citation_public_url	https://hdl.handle.net/11094/99833

Liver Failure From Ultra-Short Bowel Syndrome on the Intestinal Transplant Waiting List: A Retrospective Study

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